Xianrong Xu

ORCID: 0000-0003-2406-3690
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About
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Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Vestibular and auditory disorders
  • Retinoids in leukemia and cellular processes
  • Gestational Diabetes Research and Management
  • Retinal Diseases and Treatments
  • Pregnancy and preeclampsia studies
  • High Altitude and Hypoxia
  • Hearing, Cochlea, Tinnitus, Genetics
  • Acute Kidney Injury Research
  • Health disparities and outcomes
  • Bariatric Surgery and Outcomes
  • Dialysis and Renal Disease Management
  • MicroRNA in disease regulation
  • Mesenchymal stem cell research
  • Tissue Engineering and Regenerative Medicine
  • Folate and B Vitamins Research
  • Ear Surgery and Otitis Media
  • Intergenerational Family Dynamics and Caregiving
  • Protein Hydrolysis and Bioactive Peptides
  • Adipokines, Inflammation, and Metabolic Diseases
  • Ophthalmology and Visual Impairment Studies
  • Spaceflight effects on biology
  • Electrospun Nanofibers in Biomedical Applications
  • Air Quality and Health Impacts
  • Cancer-related molecular mechanisms research

Hangzhou Normal University
2015-2025

Jiangsu Province Hospital
2009-2024

Tongde Hospital of Zhejiang Province
2013-2024

Nanjing Medical University
2009-2024

Jiangsu University
2024

Affiliated Hospital of Jiangsu University
2024

Air Force General Hospital PLA
2000-2022

Weatherford College
2014-2022

People's Liberation Army Air Force
2016-2021

Chongqing University of Technology
2021

Abstract Background Women with antenatal depression often have a higher risk of developing postpartum (PPD) after delivery. A number factors associated the PDD in those previously reporting been suggested, but further research is needed. This study aimed to investigate subsequent postnatal women who had screened positive for depression. Methods was carried out Hangzhou women’s Hospital. 578 experienced from this cohort were enrolled study. The sociodemographic and clinical characteristics...

10.1186/s12888-023-05030-1 article EN cc-by BMC Psychiatry 2023-08-01

Purpose . To compare the 2-year effect of multiple doses lutein/zeaxanthin on serum, macular pigmentation, and visual performance patients with early age-related degeneration (AMD). Methods In this randomized, double-blinded, placebo-controlled trial, 112 AMD randomly received either 10 mg lutein, 20 a combination lutein (10 mg) zeaxanthin mg), or placebo daily for 2 years. Serum concentration lutein/zeaxanthin, pigment optical density (MPOD), functions including best-spectacle corrected...

10.1155/2015/564738 article EN cc-by BioMed Research International 2015-01-01

Two novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides (YPF and LLLP) were discovered from goat milk protein by peptidomics, in silico analysis, vitro assessment. A total of 698 (<23 AA) successfully identified LC-MS/MS hydrolysates (hydrolyzed papaian plus proteinase K). Then, 105 potential DPP-IV screened using PeptideRanker, the ToxinPred tool, Libdock, iDPPIV-SCM, sequence characteristics. After ADME, physicochemical property evaluation, a literature search, 12 candidates...

10.3390/foods13081194 article EN cc-by Foods 2024-04-14

The aim of the present study was to evaluate effects lutein and lycopene supplementation on carotid artery intima–media thickness (CAIMT) in subjects with subclinical atherosclerosis. A total 144 aged 45–68 years were recruited from local communities. All randomly assigned receive 20 mg lutein/d ( n 48), lutein/d+20 lycopene/d 48) or placebo for 12 months. CAIMT measured using Doppler ultrasonography at baseline after months, serum concentrations determined HPLC. Serum increased...

10.1017/s0007114513002730 article EN British Journal Of Nutrition 2013-09-19

The purpose of this study was to determine the effects lutein supplement on serum cytokines, apoE and lipoprotein profiles in early atherosclerosis population.Early patients (n= 65) were randomized receive placebo (A+P, n= 31) or 20 mg/d (A+L, 34) for 3 months.Serum increased significantly compared baseline after supplements A+L group (p<0.001). Lutein resulted a significant decrease interleukin-6 (IL-6) monocyte chemoattractant protein-1 (MCP-1) at month (p<0.05). Intragroup comparison...

10.5551/jat.14365 article EN cc-by-nc-sa Journal of Atherosclerosis and Thrombosis 2012-11-14

OBJECTIVE Evidence of the associations between fine particulate matter (PM2.5) and diabetes risk from women reproductive age, in whom may have adverse long-term health effects for both themselves future generations, remains scarce. We therefore examined PM2.5 exposure with fasting blood glucose (FBG) level age China. RESEARCH DESIGN AND METHODS This study included 20,076,032 20–49 years participating National Free Preconception Health Examination Project China 2010 2015. was estimated using...

10.2337/dc23-2153 article EN Diabetes Care 2024-05-22

<h3>Aims</h3> To investigate functional and macular pigment (MP) changes in patients with early age-related degeneration (AMD) after multiple supplementation lutein zeaxanthin. <h3>Methods</h3> 112 AMD were randomly (1:1:1:1) assigned to receive 10 mg lutein, 20 (10 mg)+zeaxanthin mg), or placebo daily for 2 years. MP optical density (MPOD) was recorded at baseline, 48 weeks Retinal sensitivities measured by multifocal electroretinogram peak-to-trough amplitude (N1P1) baseline weeks, terms...

10.1136/bjophthalmol-2014-305503 article EN British Journal of Ophthalmology 2014-09-16

Abstract Background Literature about life satisfaction in rural senior older adults is scarce. The aim of this research was to examine the relationships among mental health, social capital and adults. Methods This a cross-sectional study. From July October 2017, 245 from 14 villages Jinhua City China were recruited. Satisfaction with Life Scale (SWLS), Chinese Version 12-item General Health Questionnaire (GHQ-12), Social Capital (SCQ) self-designed questionnaire administered participants....

10.1186/s12877-022-02761-w article EN cc-by BMC Geriatrics 2022-01-24

Dietary phytoestrogens have been suggested to provide protection against numerous age-related diseases. However, their effects on biological aging remain unclear. In this study, we cross-sectionally investigated the relationship between urinary phytoestrogen levels and indicators of using data from 7,981 adults who participated in National Health Nutrition Examination Survey 1999–2010. Urinary concentrations six phytoestrogens, including four isoflavones two enterolignans, were measured...

10.1038/s41598-025-88872-x article EN cc-by-nc-nd Scientific Reports 2025-03-12

Objective To investigate the effects of coupled plasma filtration adsorption (CPFA) on immune function patients with multiple organ dysfunction syndrome (MODS). Methods This study was a prospective, pilot, before-and-after self-crossover, clinical trial. Seven diagnosed MODS and severe infection were randomly allocated to both 10 hours CPFA high-volume hemofiltration (HVHF) 12-hour interval in random order. Serum concentrations 7 cytokines including tumor necrosis factor-α (TNF-α),...

10.1177/039139880903200104 article EN The International Journal of Artificial Organs 2009-01-01

We aimed to examine the effect of different doses lutein supplementation on visual function in subjects with long-term computer display light exposure. Thirty-seven healthy exposure ranging age from 22 30 years were randomly assigned one three groups: Group L6 (6 mg lutein/d, n 12); L12 (12 13); and Placebo (maltodextrin placebo, 12). Levels serum performance indices such as acuity, contrast sensitivity glare measured at weeks 0 12. After 12-week supplementation, concentrations Groups...

10.1017/s0007114508163000 article EN British Journal Of Nutrition 2009-02-19

Objective: To determine the risk factors of occurrence nonsyndromic cleft lip and/or palate (NSCL/P) in Xinjiang Province, China. Design: The study included 359 patients NSCL/P and 310 controls. Information about sociodemographic characteristics, lifestyle behaviors, negative life events, possible environmental hazards exposures, use supplementations were collected from cases Both t test χ 2 tests used for group comparisons. Multivariable logistic regression was to estimate independent...

10.1177/1055665620956869 article EN The Cleft Palate-Craniofacial Journal 2020-09-14
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