A5091302164- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Public Health and Social Inequalities
- Cardiovascular Issues in Pregnancy
- Global Maternal and Child Health
- Public Health and Environmental Issues
- HIV/AIDS Research and Interventions
- Insect symbiosis and bacterial influences
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Parasitic Infections and Diagnostics
Administración Nacional de Laboratorios e Institutos de Salud
2014-2025
Asociación por los Derechos Civiles
2020
With the control of vectorial and transfusional routes infection with Trypanosoma cruzi, congenital transmission has become an important source new cases. This study evaluated efficacy trypanocidal therapy to prevent Chagas disease compared clinical serological evolution between treated untreated infected mothers. We conducted a multicenter, observational on cohort mothers T. without treatment before pregnancy. Their children were studied detect infection. Among 354 "chronically...
Background Trypanosoma cruzi is a protozoan parasite which causes Chagas disease. Mother-to-child transmission the main route of in vector-free areas. Congenital disease refers specifically to cases arising from this transmission. This work evaluates clinical sensitivity two qPCR techniques for diagnosis congenital Methods The study was developed National Institute parasitology (NIP), Argentina, and Pan-American Health Organization/ Word Organization Collaborating Center Disease. Between...
BackgroundCurrent algorithm for Congenital Chagas Disease (cCD) diagnosis is unsatisfactory due to low sensitivity of the parasitological methods. Moreover, loss follow-up precludes final serodiagnosis after nine months life in many cases. A duplex TaqMan qPCR kit Trypanosoma cruzi DNA amplification was prospectively evaluated umbilical cord (UCB) and peripheral venous blood (PVB) infants born CD mothers at endemic non-endemic sites Argentina.MethodsWe enrolled followed-up 370 infants;...
Infection by Trypanosoma cruzi (Chagas disease [ChD]) affects around 7 million people in the Americas, most of whom are unaware their status due to lack clinical manifestations and poor access diagnosis. Rapid diagnostic tests (RDTs) widely used for screening different infections (HIV, hepatitis B, syphilis), application ChD would facilitate diagnosis, especially remote areas where health services have scarce resources. We conducted a prospective intervention study 2018 evaluate field two...
Congenital transmission (CT) of Trypanosoma cruzi has led to globalization Chagas disease and its growing relevance as a public health problem. Although the occurrence CT been associated with several factors, mechanisms are still unknown. This study aimed analyze geographical familiar variables mothers their association in population living non-endemic areas Argentina for last decades.We developed retrospective cohort sample 2120 mother-child pairs who attended three reference centers cities...
Abstract Background Retrospective observational studies suggest that transmission of Trypanosoma cruzi does not occur in treated women when pregnant later life. The level parasitemia is a known risk factor for congenital transmission. Benznidazole (BZN) the drug choice preconceptional treatment to reduce parasitic load. fear treatment-related side effects limits implementation Argentine guideline recommending BZN 60d/300mg (or equivalent) T. seropositive during postpartum period prevent...
Abstract Background Retrospective observational studies suggest that transmission of the Trypanosoma cruzi does not occur in treated women when pregnant later life. The level parasitemia is a known risk factor for congenital transmission. Benznidazole (BZN) drug choice preconceptional treatment to reduce parasitic load. BENEFIT trial, conducted Argentina, compared BZN 60-day/300 mg per day (60d/300mg) course (for subjects weighing 60kg) vs. placebo among patients with Chagas’ cardiomyopathy....
El objetivo de este estudio fue indagar sobre experiencias y percepciones del personal salud (PDS) Argentina en la implementación protocolos para su protección durante pandemia por COVID-19. Se realizó una encuesta al PDS a nivel nacional, relevando datos sociodemográficos, protocolos, recursos aspectos psicosociales. analizaron 2010 encuestas. 76.4% fueron mujeres, 43 años edad media, 35% médicos/as 72.7% subsistema público. 37.2% aumentó carga horaria el 22.5% presentaba algún factor...