A5050738358- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Fetal and Pediatric Neurological Disorders
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Spinal Fractures and Fixation Techniques
- Craniofacial Disorders and Treatments
- Head and Neck Surgical Oncology
- Neuroblastoma Research and Treatments
- Vascular Malformations Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Child Abuse and Related Trauma
- Cleft Lip and Palate Research
- Neonatal and fetal brain pathology
- Traumatic Brain Injury Research
- Parasitic infections in humans and animals
- Spine and Intervertebral Disc Pathology
- Ocular Disorders and Treatments
- Infectious Diseases and Tuberculosis
- Brain Metastases and Treatment
- Family and Disability Support Research
Aix-Marseille Université
2021
Hôpital de la Timone
1994-2020
Délégation Provence et Corse
2009
Hôpital des Enfants
1978-2006
Ospedale Bellaria
2006
Heinrich Heine University Düsseldorf
2006
Düsseldorf University Hospital
2006
Hôpital Nord
1997
Centers for Disease Control and Prevention
1994
Hôpital Charles-Nicolle
1992
The occurrence of intracranial ependymomas in children is relatively infrequent, and their prognostic factors are still controversial, especially regarding histological composition.A retrospective study was conducted 37 treated during the last 20 years for at Hôpital de la Timone. Both univariate multivariate statistical analyses were performed to assess relevance patient age sex, extent tumor removal, location (supratentorial compared with infratentorial, median lateral), composition,...
Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial.To determine factors influence prognosis patients with astrocytomas, a series 73 consecutive at 13 French treatment centers histologically proven astrocytomas was retrospectively reviewed. Hospital records, operative results radiologic investigations were available in all cases. Follow-up achieved 94% cases.Seventy percent had low grade (1 or 2) tumors. Total subtotal surgical...
The authors have studied the clinical features of 104 extradural hematomas in children. frequency this complication seems rather high and its severity undeniable. 17 cases were observed newborns 2 localized posterior fossa. From a point view, 57% children had no disturbances consciousness at time injury, 7% anytime. A lucid interval was found 68% cases, less than 24 h 60% cases. In 19% there skull fracture. Angiography allowed correct diagnosis better choice surgical technique. hematoma...
The intracranial, liquid-containing cysts in children (excluding tumor and parasitic cysts) are relatively frequent neurosurgical practice. They raise several problems about their nosology, etiology, clinical radiological diagnosis, treatment which analyzed a series of 36 cases supratentorial cysts. most feature is increased head circumference (22 cases) followed by epileptic fits (18 cases), as well mental motor retardation (19 cases). Fun-di were found abnormal only one case out three....
✓ The aim of this study was to evaluate the feasibility and efficacy a protocol that includes “sandwich” chemotherapy, is, chemotherapy alternated with radiotherapy, reduced doses supratentorial irradiation in children medulloblastoma. Between March 1985 September 1988, 70 successive newly diagnosed medulloblastoma from eight centers were treated prospective nonrandomized study. Patients assigned two risk groups. Group A included patients macroscopically complete or subtotal excision, no...
Brain tumors are the most frequent childhood tumors. There have been few cytogenetic studies published on these in children compared to numerous adult brain We examined chromosomes from 45 primary pediatric neoplasms including 14 medulloblastomas, 12 astrocytomas, 4 glioblastomas, 7 ependymomas, 5 craniopharyngiomas, 2 meningiomas, and 1 ganglioglioma. Chromosomal abnormalities were found 10 medulloblastomas out of analyzed. The frequently observed total or partial loss one chromosome 17:...
An unusual cerebral tumor is reported in a ten-month-old boy. The was large (10 cm x 6 cm), firm and included several cysts. Light electron microscopy showed striking cellular pleomorphism. Typical neurosecretory ganglion cells were observed, always surrounded by Schwann cells. Amyelinic neurites, clusters of cells, fibroblasts numerous foci GFA positive astrocytes composed the tumor. These features compared with rare previous microscopic reports neuronal central nervous system. A...
The authors present aspects of the skull base in trigonocephalic children. Different patterns on clinical anthropometric investigation, bidimensional computer tomography (CT) scan and three-dimensional (3D) CT were studied. We a series 27 cases trigonocephaly operated department pediatric neurosurgery at Hôpital des enfants La Timone Marseille since 1975. has been studied with 12 patients 5 3D reconstruction was performed. A control children without synostosis same patterns. have analyzed...
Object The goal of this study was to assess the effectiveness and handling characteristics a dura substitute composed two outer layers expanded polytetrafluoroethylene (PTFE) middle layer consisting an elastomeric fluoropolymer. Methods In prospective multicenter study, implanted using standard technique in 119 patients undergoing cranial or spinal surgery requiring duraplasty. Intraoperative assessments patch consisted testing for cerebrospinal fluid (CSF) leakage employing Valsalva...