A5020001082- Ion Channels and Receptors
- Calcium signaling and nucleotide metabolism
- Piperaceae Chemical and Biological Studies
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- Bioactive Compounds and Antitumor Agents
- CRISPR and Genetic Engineering
- Advanced Electron Microscopy Techniques and Applications
- Bacterial Genetics and Biotechnology
- Advanced Fluorescence Microscopy Techniques
Universität Hamburg
2015-2018
University Medical Center Hamburg-Eppendorf
2015-2018
Osnabrück University
2014-2016
High-resolution imaging of live T cells characterizes the early Ca 2+ signals required for cell activation.
The proteins that generate Ca 2+ signals within the first second after T cell activation are identified.
Abstract The investigation of the subcellular localization, dynamics and interaction proteins protein complexes in prokaryotes is complicated by small size cells. Super-resolution microscopy (SRM) comprise various new techniques that allow light with a resolution can be up to ten-fold higher than conventional microscopy. Application SRM living demands introduction suitable fluorescent probes, usually fusion interest properties compatible SRM. Here we describe an approach based on genetically...