A5026794011- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Cancer Studies
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Surgical Oncology
- Allergic Rhinitis and Sensitization
- Oral and Maxillofacial Pathology
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Vestibular and auditory disorders
- Cancer Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Head and Neck Anomalies
- Meningioma and schwannoma management
- Thyroid Cancer Diagnosis and Treatment
- Sinusitis and nasal conditions
- Tumors and Oncological Cases
- Airway Management and Intubation Techniques
- Dermatology and Skin Diseases
- Peptidase Inhibition and Analysis
- Neuroblastoma Research and Treatments
- Vascular Malformations and Hemangiomas
- Ophthalmology and Eye Disorders
- Trigeminal Neuralgia and Treatments
- Boron Compounds in Chemistry
Osaka University of Pharmaceutical Sciences
2021-2025
Rakuwakai Otowa Hospital
2024
Osaka Medical and Pharmaceutical University
2013-2022
Individual Differences
2022
Weatherford College
2022
Shizuoka University
2011
Kyoto Prefectural University of Medicine
1987-2000
Krankenhaus vom Roten Kreuz
1991-2000
Yawata Medical Center
2000
Red Cross Hospital
1990-2000
Abstract Background Chronic rhinosinusitis ( CRS ) can be classified into with nasal polyps w NP and without s ). displays more intense eosinophilic infiltration the presence of Th2 cytokines. Mucosal eosinophilia is associated severe symptoms often requires multiple surgeries because recurrence; however, even in ECRS ), clinical course variable. In this study, we wanted to set objective criteria for diagnosis refractory . Methods This was a retrospective study conducted by 15 institutions...
Strong eosinophil infiltration in chronic rhinosinusitis with nasal polyp (CRSwNP) is highly associated recalcitrance and higher recurrence rate after surgery. The prevalence of eosinophilic CRSwNP (ECRS) increasing Asian countries including Japan. Benralizumab a humanized anti-IL-5R alpha monoclonal antibody that depletes eosinophils by antibody-dependent cell-mediated cytotoxicity.To assess the efficacy safety benralizumab patients ECRS.This phase II, randomized, double-blind,...
Abstract Purpose Since June 2020, boron neutron capture therapy (BNCT) has been a health care service covered by insurance in Japan to treat locally advanced or recurrent unresectable head and neck cancers. Therefore, we aimed assess the clinical outcomes of BNCT as treatment explore its role among standard modalities for Materials Methods We retrospectively analyzed data from patients who were treated using at Kansai Medical Center, Osaka Pharmaceutical University, between 2020 May 2022....
Elective neck dissection (END) may not be necessary in patients with low-grade malignancy. However, currently, END should performed all parotid carcinoma because the preoperative diagnosis of lymph node metastasis is limited and accuracy grade low.Our aim was to examine indication for N0 extent by investigating diagnosing carcinoma.The subjects were 77 carcinoma. Among patients, modified radical (MRND) conducted those whom histological evaluated as high, selective (SND) other patients.Lymph...
Activation of MMC-34 cells, a murine mast cell line, or bone marrow-derived cells by aggregation IgE surface receptors addition calcium ionophore stimulates prostaglandin (PG) D2 synthesis and secretion. An initial rapid burst PGD2 synthesis, complete within 30 min, is followed slower subsequent production that reaches maximum 4 to 8 h after activation in cells. PG synthase 1 (PGS-1) message protein are expressed constitutively not modulated exposure receptors. In contrast, induces...
The relationship between chronic rhinosinusitis (CRS) and asthma has been known for a long time. However, no large studies on the CRS lower airway diseases have reported to date in Japan. Additionally, eosinophilic (ECRS) Japan is considered be subgroup of with nasal polyps (CRSwNP) characterized by eosinophil-dominant inflammation. diagnostic criteria ECRS not established. To investigate clinical epidemiological features patients from aspect their associations diseases, 553 who visited one...
Three pathological grading systems advocated by Perzin/Szanto, Spiro, and van Weert are currently used for adenoid cystic carcinoma (AdCC). In these systems, the amount or presence of solid tumor component in AdCC specimens is an important index. However, "solid component" has not been well defined. Salivary cases (N = 195) were collected after a central pathology review. We introduced novel criterion component, minAmax (minor axis maximum). The largest nest each case was histologically...
Mucoepidermoid carcinoma (MEC) is rare, but the most common primary malignancy of salivary gland and not infrequent in young individuals. CRTC1/3-MAML2 fusions are frequently detected MEC useful as a diagnostic biomarker. However, there has been debate to whether have prognostic significance. In this study, we retrospectively collected 153 cases from 11 tertiary hospitals Japan. As inclusion criteria, patients study had curative surgery initial treatment, received no preoperative distant...
Objective The aim of this study was to evaluate the rate postoperative facial palsy in benign parotid tumors, as well its risk factors, pathology, and clinical results. Study Design Retrospective analysis. Methods We performed a retrospective analysis data from patients whose initial operation for tumor had been our department between 1999 2020. Results included 1,018 study. most common observed pleomorphic adenoma (614 patients), followed by Warthin (234 patients). Fine‐needle aspiration...
Biochemical, histologic, and computed tomographic (CT) examinations of the liver were performed in 32 rabbits which fatty was induced by prolonged intravenous fat infusion. In two groups rabbits, 2 4 g/kg/day emulsion administered, respectively, posttreatment reduction CT value mild degree observed, but insignificant from standpoint diagnosis images. group that received 8 emulsion, change -14.9 +/- 5.1 H, a sufficient for moderate degree. No significant seen no-treatment or 80 ml/kg/day...
This study investigated the clinical outcomes of patients with parotid carcinoma at a single institution during an 18-year period, focus on diagnosis, treatment, and survival. The subjects were 171 treated our department period from September 1999 to August 2017. There 19 in stage I, 65 II, 22 III, IV. symptoms, preoperative node metastasis, survival rate, prognostic factors, immunohistological findings investigated. Preoperative diagnosis histological grade by fine-needle aspiration...
// Kazumasa Moriwaki 1, * , Yusuke Ayani 2, Hiroko Kuwabara 3 Tetsuya Terada 2 Ryo Kawata and Michio Asahi 1 Department of Pharmacology, Faculty Medicine, Osaka Medical College, Takatsuki, 569-8686, Japan Otolaryngology-Head Neck Surgery, Pathology, These authors contributed equally to this work Correspondence to: Asahi, email: masahi@osaka-med.ac.jp Keywords: TRKB; oral squamous cell carcinoma; tumor differentiation; prognostic factors; anti-cancer drug Received: August 09,...
Background: Intralymphatic immunotherapy (ILIT) for allergic patients requires only a few intralymphatic injections of the allergen.However, effectiveness and safety Japanese cedar pollinosis are unclear.The objectives this study were to clarify whether how long ILIT is effective pollinosis, its safety. Methods:In an open pilot investigation followed by double-blind, placebo-controlled study, with received 3 inguinal pollen extracts before first season.The symptom medication score (SMS),...