Göran Isacsson

ORCID: 0000-0003-2431-5173
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About
Contact & Profiles
Research Areas
  • Suicide and Self-Harm Studies
  • Treatment of Major Depression
  • Mental Health Treatment and Access
  • Temporomandibular Joint Disorders
  • Obstructive Sleep Apnea Research
  • Poisoning and overdose treatments
  • Oral and Maxillofacial Pathology
  • Child and Adolescent Psychosocial and Emotional Development
  • Neuroscience of respiration and sleep
  • Salivary Gland Tumors Diagnosis and Treatment
  • Salivary Gland Disorders and Functions
  • Tracheal and airway disorders
  • Schizophrenia research and treatment
  • Bipolar Disorder and Treatment
  • Oral Health Pathology and Treatment
  • Botulinum Toxin and Related Neurological Disorders
  • dental development and anomalies
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Child and Adolescent Health
  • Animal Ecology and Behavior Studies
  • Dental materials and restorations
  • Mental Health Research Topics
  • Health disparities and outcomes
  • Pain Mechanisms and Treatments
  • Psychosomatic Disorders and Their Treatments

Västmanlands sjukhus Västerås
2016-2024

Mälardalen University
2023-2024

Örebro University
1989-2024

Uppsala University
2017-2024

Center for Clinical Research Dalarna
2019

Karolinska Institutet
2009-2018

Karolinska University Hospital
2004-2014

County Hospital
2014

Landstinget Sörmland
2007-2009

Stockholm County Council
2008

Objective: The author hypothesized, based on research until 1991, that a five‐fold increase in the use of antidepressants might reduce Swedish suicide rates by 25%. A subsequent 3.5‐fold provided ‘natural experimental situation’ forprospectively testing this hypothesis. Method: statistics suicide, antidepressants,unemployment and alcohol consumption were obtained for1978–96. Time‐series latter variables compared with rates. Demographic subgroups regarding age, gender county analysed. Suicide...

10.1034/j.1600-0447.2000.102002113.x article EN Acta Psychiatrica Scandinavica 2000-08-01

Background It is unclear whether there a direct link between economic crises and changes in suicide rates. Aims The Lopez-Ibor Foundation launched an initiative to study the possible impact of crisis on European Method Data was gathered analysed from 29 countries included number deaths by men women, unemployment rate, gross domestic product (GDP) per capita, annual growth rate inflation. Results There strong correlation rates all indices except GPD capita but only with women. However,...

10.1192/bjp.bp.114.147454 article EN The British Journal of Psychiatry 2014-10-31

Objective: To test the hypothesis that selective serotonin reuptake inhibitor (SSRI) antidepressants may have a suicide emergent effect, particularly in children and adolescents. Method: Detections of different forensic toxicological screening 14 857 suicides were compared with those 26 422 cases deaths by accident or natural causes Sweden 1992–2000. Results: There 3411 detections 1538 controls. SSRIs had lower odds ratios than other antidepressants. In 52 under 15 years, no detected....

10.1111/j.1600-0447.2004.00504.x article EN Acta Psychiatrica Scandinavica 2005-03-01

It is well known that suicidal rates vary considerably among European countries and the reasons for this are unknown, although several theories have been proposed. The effect of economic variables has extensively studied but not climate. Data from 29 covering years 2000–2012 concerning male female standardized (according to WHO), World Bank) climate were gathered. statistical analysis included cluster principal component categorical regression. derived models explained 62.4 % variability...

10.1186/s12991-016-0106-2 article EN cc-by Annals of General Psychiatry 2016-08-09

Antidepressants detected by the National Department of Forensic Chemistry in 5281 suicides Sweden during period 1992‐1994 were related to data on usage expressed person‐years exposure. 874 subjects (16.5%). In relation their use, fluvoxamine, citalopram, moclobemide, mianserin and trimipramine found more often than reference drug, amitriptyline (i.e. over‐risks). Toxic concentrations antidepressants 232 (4.4%). Most people committing suicide not taking immediately before death, even though...

10.1111/j.1600-0447.1997.tb09912.x article EN Acta Psychiatrica Scandinavica 1997-08-01

Abstract The use of antidepressants has been low in Jämtland County for many years, while the suicide rate among highest Sweden. A continuous outpatient prescription recording system operation since 1970. Through this we traced pattern 80 individuals who committed from 1970 to 1984. Suicide patients obtained 1.5 times more drugs than matched controls, mainly psychotropics and vitamins. During 3 months prior suicide, half had received medical attention 73% women 40% men drugs, one‐third...

10.1111/j.1600-0447.1992.tb03209.x article EN Acta Psychiatrica Scandinavica 1992-06-01

Ecological studies have demonstrated a substantial decrease in suicide parallel with an increase the use of antidepressants. Causality cannot, however, be inferred from such studies. The aim this study was to test on individual level hypothesis that treatment antidepressant medication has been substantially contributing cause suicide.Time trends detection antidepressants and five 'control medications' forensic toxicological screening 16 937 suicides 33 426 controls Sweden 1995-2005.The...

10.1111/j.1600-0447.2009.01344.x article EN Acta Psychiatrica Scandinavica 2009-02-16

Summary Numerous ecological studies have shown an inverse association between antidepressant use and suicide rates a smaller number of individual-based current reduced risk. Such evidence is often cited in support the notion that antidepressants prevent suicide. However, more recently, premises underlying this proposition, namely caused by depression relieve depression, been challenged potential harm has highlighted. In article, Goran Isacsson Charles Rich debate with Jon Jureidini Melissa...

10.1192/bjp.bp.109.076166 article EN The British Journal of Psychiatry 2010-05-31

Objective: To consider and evaluate a continuing medical education programme for general practitioners (GPs) on depression in Jämtland county, Sweden, inspired by the Gotland study. Method: Interactive seminars were conducted between 1995 2002 county. For evaluation, suicide rates annual sales statistics of antidepressants compared with national averages. Questionnaires used information about attitudes prescribing habits. Results: The rate decreased to same level as average. use increased...

10.1111/j.1600-0447.2006.00822.x article EN Acta Psychiatrica Scandinavica 2006-05-24

To assess the possible relationship between major depression (MD) and nocturia.An unselected group of adult men women, living in city Ostersund, Sweden, were sent a postal questionnaire containing questions on somatic mental health, sleep, sleepiness nocturia. For diagnostics Major Depression Inventory (MDI) was used.The mean (sd) ages women 48.0 (18.2) 50.1 (19.1) years, respectively. Two or more nocturnal micturition episodes occurred 15.6% 16.5% women. In multiple logistic regression...

10.1111/j.1464-410x.2004.04835.x article EN BJU International 2004-05-27

Ten temporomandibular joint specimens, five with clinical signs of arthropathology and without, were examined by means tomography, double-contrast serial cryosectioning combined histologic staining sections for tissue identification. Of the joints four demonstrated disc displacement. The fifth showed a post-traumatic condition. Four hyperplastic connective retaining contrast medium in posterior part fossa. This contained extravasated blood enlarged cavernous structures lacking endothelial...

10.3109/00016358609026568 article EN Acta Odontologica Scandinavica 1986-01-01

Background The increasing incidence of mental health problems among young people is a major concern in many Western countries. causal mechanisms underlying these trends are not well established, but factors influenced by current societal changes ought to be implicated. Such include immigration and social adversity as the timing taking on adult roles (e.g. gainful employment, parenthood own housing tenure). We therefore examined relationships between risks psychological distress suicide...

10.1371/journal.pone.0046284 article EN cc-by PLoS ONE 2012-10-03
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