Xiaojun Wang

ORCID: 0000-0003-2432-511X
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About
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Research Areas
  • Soil Carbon and Nitrogen Dynamics
  • Cancer, Hypoxia, and Metabolism
  • Ferroptosis and cancer prognosis
  • Peatlands and Wetlands Ecology
  • MicroRNA in disease regulation
  • Bioenergy crop production and management
  • Cancer Mechanisms and Therapy
  • Soil and Unsaturated Flow
  • Neurogenesis and neuroplasticity mechanisms
  • Mesenchymal stem cell research
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Hepatitis B Virus Studies
  • Microbial Community Ecology and Physiology
  • Cancer, Lipids, and Metabolism
  • RNA modifications and cancer
  • Genomics, phytochemicals, and oxidative stress
  • Climate change and permafrost
  • Cancer-related molecular mechanisms research

Beijing YouAn Hospital
2022-2025

Capital Medical University
2022-2025

Institute of Soil and Water Conservation
2024

Ministry of Water Resources of the People's Republic of China
2024

Northwest A&F University
2024

Hepatocellular carcinoma (HCC) is still a public health disease with its high prevalence and morbidity. Short of early diagnosis biomarkers effective therapy, the treatment HCC patients hasn't achieved ideal effect. Hypoxia hallmark HCC, which mainly induced by imbalance tumor cell proliferation insufficient supply oxygen. Recently, amounting evidence suggested lncRNAs, especially hypoxia-related lncRNAs play pivotal role in regulating HCC. Hypoxia-related are involved altering glucose...

10.1007/s12672-024-01002-3 article EN cc-by Discover Oncology 2024-05-07

Abstract Background Hepatocellular carcinoma (HCC) poses ongoing difficulties for public health systems due to its high incidence and poor prognosis. Huqi formula (HQF), a well-known prescription in traditional Chinese medicine, has demonstrated notable clinical effectiveness the treatment of HCC. However, mechanisms underlying therapeutic effects have yet be completely elucidated. Purpose This study aimed investigate anti-HCC HQF mechanisms. Methods Chemical profiling quantification were...

10.1186/s13020-025-01061-w article EN cc-by Chinese Medicine 2025-02-19

Background: Hepatocellular carcinoma (HCC) is a common clinical malignant tumor of the digestive system. Hu-Qi-Zheng-Xiao (HQZX) decoction has been clinically found to prolong survival patients with hepatocellular and improve quality patients’ survival, but its antitumor biological mechanism still unclear. Methods: A nude mouse hollow fiber model was constructed analyze in vivo efficacy HQZX against 7 different cells. The subcutaneous graft again validated. In vitro, effect on growth...

10.1177/15347354231226126 article EN cc-by-nc Integrative Cancer Therapies 2024-01-01

Despite the considerable progress in mesenchymal stem/stromal cells (MSCs)-based novel intervention of multiple sclerosis (MS), yet disease-modifying effect VCAM-1− MSCs and VCAM-1+ counterpart is largely obscure. In this study, we took advantage EAE mouse model human umbilical cord-derived (hUC-MSCs) for evaluation therapeutic systematic infusion. On one hand, compared protective hUC-MSCs against clinical symptoms, demyelination, active glia neuroinflammation mice by conducting multifaceted...

10.1007/s11064-024-04267-w article EN cc-by-nc-nd Neurochemical Research 2024-11-30
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