A5084396054- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Management of metastatic bone disease
- Medical Imaging and Analysis
- Pelvic and Acetabular Injuries
- Orthopaedic implants and arthroplasty
- Multiple Myeloma Research and Treatments
- Bone health and treatments
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Hip disorders and treatments
- Bone and Joint Diseases
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Foot and Ankle Surgery
- Shoulder Injury and Treatment
- Clinical practice guidelines implementation
- Sarcoma Diagnosis and Treatment
- Total Knee Arthroplasty Outcomes
- Global Peace and Security Dynamics
- Cancer Treatment and Pharmacology
- Spinal Dysraphism and Malformations
- Cervical and Thoracic Myelopathy
- Childhood Cancer Survivors' Quality of Life
University College London
2014-2023
Royal National Orthopaedic Hospital
2014-2023
Stanmore College
2015-2023
North York General Hospital
2023
Rush University
2022
Cancer Care Ontario
2013-2018
St Joseph's Health Centre
2015-2018
Smith College
2018
University of Memphis
2018
Texas A&M University
2018
Study Design. Ex vivo biomechanical study using osteoporotic cadaveric vertebral bodies. Objective. To measure internal body temperature during polymerization of cements used for vertebroplasty. Summary Background Data. Previous ex studies have shown that increases cement were unlikely to cause thermal necrosis. Methods. Twenty-four bodies instrumented with thermocouples and injected one two volumes (6 or 10 mL) (Simplex P modified Simplex P, Stryker-Howmedica-Osteonics, Kalamazoo, MI)....
An ex vivo biomechanical study was conducted using osteoporotic cadaveric vertebral bodies.To determine the relationship between percentage of body volume filled with polymethylmethacrylate cement during percutaneous vertebroplasty and restoration strength stiffness.A previous reported a weak injected stiffness. Vertebral bodies vary considerably in size among regions spines, correlation may be attributed to fact that not explicitly considered.The 120 (T6-L5) harvested from 10 female cadaver...
Abstract Multiple myeloma (MM) represents approximately 15% of haematological malignancies and most the patients present with bone involvement. Focal or diffuse spinal osteolysis may result in significant morbidity by causing painful progressive vertebral compression fractures (VCFs) deformities. Advances systemic treatment have achieved high response rates prolonged survival significantly. Early diagnosis management skeletal events contribute to improving prognosis quality life MM patients....
To improve symptom management, the Ontario Cancer Symptom Management Collaborative uses common assessment and care management tools including Interactive Assessment Collection, which allows patients to report their symptoms via kiosks or tablets directly clinicians in real-time.
ContextCancer patients experience a high symptom burden throughout their illness. Despite this, patients' symptoms and needs are often not adequately screened for, assessed, managed.ObjectivesThis study investigated the attitudes of cancer care professionals toward standardized systematic assessment Edmonton Symptom Assessment System (ESAS) self-reported use instrument in daily practice large healthcare jurisdiction where this is routine.MethodsA 21-item electronic survey, eliciting both...
In Brief Study Design. Ex vivo biomechanical study. Objectives. To compare the properties of isolated, fractured, osteoporotic vertebral bodies after treatment by kyphoplasty with one two cements: α-tri-calcium phosphate cement (Biopex-R; Mitsubishi Materials Corp., Tokyo, Japan) or polymethylmethacrylate (Simplex P; Stryker-Howmedica-Osteonics, Mahwah, NJ). Summary Background Data. Kyphoplasty and vertebroplasty typically use cements for compression fractures. Scant information exists...
Although Pisa syndrome and scoliosis are sometimes used interchangeably to describe a laterally flexed postural deviation in Parkinson's disease (PD), the imaging findings of PD have not been previously studied detail.Patients with (lateral flexion >10° standing position) were examined clinically underwent radiological assessment using radiograph supine CT scan whole spine.Fifteen patients included this observational study. All had on radiographs, 12 persisting position. Scoliotic curves...
Scoliosis affects 50% of children with Gross Motor Function Classification System (GMFCS) level IV or V cerebral palsy (CP). In complex neurodisability following intervention, the WHO considers quality life (QoL) should be assessed to aid decision-making and assess effects. This study assesses whether scoliosis surgery improves carer-assessed QoL for severe CP.Retrospective review 33 (16 male:17 female) GMFCS IV/V CP significant scoliosis. Fifteen underwent observational treatment during...
Objectives To compare the biomechanical stability of an alternative custom-designed intramedullary nail (IMN) fixation with that traditional tension band wiring (TBW), gold standard for stabilizing transverse olecranon fractures. Design Ex vivo study. Setting Biomechanical laboratory. Materials Six pairs elderly cadaver elbows. Intervention A simulated fracture was created in each elbow after it had been denuded most its soft tissue. The right and left olecranons pair were alternately...
INTRODUCTION Acute osteoporotic vertebral compression fractures are common and usually managed conservatively. However, a significant number will remain symptomatic, causing pain with considerable associated morbidity mortality. These can be effectively treated cement augmentation. it is impossible to distinguish between an acute chronic healed fracture on plain radiographs. The definitive investigation magnetic resonance scan. aim of this paper describe evaluate two new clinical signs help...
Summary Myeloma is one of the most common malignancies that results in osteolytic lesions spine. Complications, including pathological fractures vertebrae and spinal cord compression, may cause severe pain, deformity neurological sequelae. They also have significant consequences for quality life prognosis patients. For patients with known or newly diagnosed myeloma presenting persistent back radicular pain/weakness, early diagnosis disease therefore essential to treat prevent further...
Multiple myeloma osteolytic disease affecting the spine results in vertebral compression fractures. These are painful, result kyphosis, and impact respiratory function quality of life. We explore time to presentation on efficacy spinal treatment modalities.We retrospectively reviewed 183 patients with presenting our service over a 2 year period.Median from multiple diagnosis at centre was 195 days. Eighty-four (45.9 %) were treated balloon kyphoplasty remainder thoracolumbar-sacral orthosis...
Ankle fractures are common and many require surgical intervention. It has been well documented that a delay in fracture fixation results increased length of hospital stay complication rate. Initial can also allow swelling or blistering to develop which may necessitate further operative for up 1 week. The aim the current study was review in-patient ankle over previous 12-month period at our compare this following introduction fast-track system these (all fixed within 48 h).A retrospective all...
Balloon kyphoplasty (BKP) is a percutaneous treatment for cancer-related vertebral compression fractures (VCF). Posterior body wall (PVBW) involvement considered contraindication BKP. This study assesses whether BKP safe and effective VCFs involving the PVBW.This analyzed data on 158 patients with 228 who underwent One hundred twelve had PVBW defects, 46 no defect. Outcomes were assessed preoperatively at 3 months.In defect group, mean pain score decreased from 7.5 to 3.6 (P < 0.001), EQ5D...
Osseous metastases occur in 50% of patients with renal cell carcinoma; these, 15% the spine. The treatment options for spinal secondary to carcinoma are limited. This paper considers current management available carcinoma.A review four carcinoma.The presentation cases highlighting carcinoma.Historically, from have been poorly managed; however, as primary disease improves, better is needed. Cement augmentation, used alone prophylactic stabilisation or conjunction a posterior decompression and...
Dedifferentiated chordomas are rare high-grade malignant spinal tumors for which there is minimal information to help guide treatment.To identify prognostic factors associated with increased risk of local recurrence, metastases, and reduced survival in a cohort patients undergoing sacrectomy de novo dedifferentiated sacral chordoma.Ten histologically confirmed chordoma at specialist center were reviewed. There 6 male 4 female mean age 66.7 years (range, 57-80 years) follow-up 36.7 months...