A5024400605- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Diagnosis and Treatment of Venous Diseases
- Spine and Intervertebral Disc Pathology
- Infectious Aortic and Vascular Conditions
- Orthopaedic implants and arthroplasty
- Vascular Procedures and Complications
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Medical Imaging and Analysis
- Spinal Fractures and Fixation Techniques
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Scoliosis diagnosis and treatment
- Renal and Vascular Pathologies
- Advanced X-ray and CT Imaging
- Atherosclerosis and Cardiovascular Diseases
- Sports injuries and prevention
- Wound Healing and Treatments
- Cardiac Health and Mental Health
- Abdominal vascular conditions and treatments
- Dermatologic Treatments and Research
- Global Health Workforce Issues
University College London
2013-2023
University College London Hospitals NHS Foundation Trust
2023
Stanmore College
2023
Royal Free London NHS Foundation Trust
2015-2023
The Royal Free Hospital
1999-2022
Royal London Hospital
2014-2021
Royal National Orthopaedic Hospital
2015-2019
Enugu State University of Science and Technology
2019
University College Hospital
2000-2018
University Hospital of the West Indies
2015
Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal aneurysms. At present, the evidence base this procedure is predominantly limited single-center or single-operator series. The aim study was present nationwide early results fenestrated in United Kingdom.All patients who underwent between January 2007 December 2010 at experienced institutions Kingdom(>10 procedures) were retrospectively studied by use...
The management and prognosis of aortic dissection (AD) is often challenging the use personalised computational models being explored as a tool to improve clinical outcome. Including vessel wall motion in such simulations can provide more realistic potentially accurate results, but requires significant additional resources, well expertise. With translation final aim, trade-offs between complexity, speed accuracy are inevitable. present study explores whether modelling worth expense case AD,...
Vascular calcification results in stiffening of the aorta and is associated with hypertension atherosclerosis. Atherogenesis a complex, multifactorial systemic process; result number factors, each operating simultaneously at several spatial temporal scales. The ability to predict sites atherogenesis would be great use clinicians order improve diagnostic treatment planning. In this paper, we present mathematical model as tool understand why atherosclerotic plaque calcifications occur specific...
To review the early outcome following endovascular repair of pararenal aortic aneurysm using fenestrated stent-grafts and to determine if number fenestrations required is predicative outcome.A retrospective analysis was conducted 20 consecutive patients (18 men; mean age 75 ± 7 years) treated with containing either ≤ 2 (n = 10, group 1) or 3 2). Target vessels also included those accommodated by a scallop (renal artery superior mesenteric in 1 celiac 2).Comorbidities were similar both...
Atherogenesis, the formation of plaques in wall blood vessels, starts as a result lipid accumulation (low-density lipoprotein cholesterol) vessel wall. Such is related to site endothelial mechanotransduction, response mechanical stimuli and haemodynamics, which determines biochemical processes regulating permeability. This interaction between biomechanical phenomena complex, spanning different biological scales patient-specific, requiring tools able capture such mathematical complexity...
Aortic dissection treatment varies for each patient and stenting is one of a number approaches that are utilized to Stabilize the condition. Information regarding hemodynamic forces in aorta dissected virtually stented cases could support clinicians their choices prior medical intervention. Computational fluid dynamics coupled with lumped parameter models have shown promise providing detailed information be used clinic; this, it necessary develop personalized workflows order produce...
The development of a new technology based on patient-specific modelling for personalised healthcare in the case atherosclerosis is presented. Atherosclerosis main cause death world and it has become burden clinical services as manifests itself many diverse forms, such coronary artery disease, cerebrovascular disease/stroke peripheral arterial disease. It also multifactorial, chronic systemic process that lasts lifetime, putting enormous financial pressure national health systems. In this...
Study Design. A retrospective review of prospectively collected data. Objective. The aim this study was to determine the safety MOLIF versus PSO. Summary Background Data. Complex adult spinal deformity (CASD) represents a challenging cohort patients. Scoli-RISK-1 has shown 22.18% perioperative risk neurological injury. Restoration sagittal parameters is associated with good outcome in ASD. Pedicle subtraction osteotomies (PSO) an important technique for balance ASD but significant morbidity....
Atherosclerosis is the main cause of mortality and morbidity in western world. a chronic disease defined by life-long processes, with multiple actors playing role at different biological time scales. Patient-specific silico models simulations can help to understand better mechanisms atherosclerosis formation, potentially improving patient management. A conceptual computational multiscale framework for modelling formation its early stage was created from integration fluid mechanics model...
Retrospective cohort study.To assess both implant performance and the amount of correction that can be achieved using multilevel anterior lumbar interbody fusion (ALIF).Retrospective study (n = 178) performed over a 4-year period. Surgical variables examined included blood loss, operative time, perioperative complications, secondary/revision procedures. Follow-up radiographic assessment was to record implant-related problems. Radiographic parameters were pre- postoperatively. Health-related...
The treatment options for an infected fenestrated endovascular aneurysm repair (FEVAR) are limited. A patient with a bi-renal FEVAR developed type 1a and 3 endoleak, destruction of the neck aneurysm, likely due to infection. In tapered thoracic aortic stent, “home-made” fenestrations were created renal arteries superior mesenteric artery. Successful coverage aorta excluded endoleaks. Life-long antibiotics commenced. There was risk imminent rupture, thus ruling out waiting custom-made FEVAR....
Endovascular repair of thoracoabdominal aortic aneurysms (TAAAs) using a branched stent graft is technically challenging procedure. A 64-year-old man with multiple medical problems, including severe renal impairment, presented ruptured type IV TAAA. He underwent emergency an off-the-shelf and carbon dioxide as the exclusive contrast agent.
Objective: To audit the prescription and implementation of deep vein thrombosis (DVT) prophylaxis in general surgical patients a teaching hospital. Methods: All inpatients on three wards were audited for adequacy (audit A). A repeat 3 months later B) closed loop. The groups compared using chi-square test. Results: In 50 participated. Prophylaxis was correctly prescribed 36 (72%) implemented 30 (60%) patients. Eighteen at moderate or high risk (45%) received inadequate prophylaxis. Emergency...