- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- ECG Monitoring and Analysis
- Aortic Disease and Treatment Approaches
- Cardiac Ischemia and Reperfusion
- Aortic aneurysm repair treatments
- Pulmonary Hypertension Research and Treatments
- Coronary Artery Anomalies
- Medical Imaging Techniques and Applications
- Renin-Angiotensin System Studies
- Acute Myocardial Infarction Research
- EEG and Brain-Computer Interfaces
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Receptor Mechanisms and Signaling
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
Kitasato University
2019-2025
Nippon Medical School
2025
Tokyo Women's Medical University Adachi Medical Center
2024
Iwate Medical University
2021-2024
Mitsubishi Electric (Japan)
2023
Tokyo Dental College Ichikawa General Hospital
2023
Tokyo Dental College
2023
Nerima General Hospital
2022
Hokkaido University
2022
Chiba University
2019
Background Recent clinical trials have demonstrated the possible pleiotropic effects of SGLT2 (sodium-glucose cotransporter 2) inhibitors in cardiovascular diseases. Atrial electrical and structural remodeling is important as an atrial fibrillation (AF) substrate. Methods Results The present study assessed effect canagliflozin (CAN), inhibitor, on a canine AF model. included 12 beagle dogs, with 10 receiving continuous rapid pacing 2 acting nonpacing group. dogs that received for 3 weeks...
Abstract Background Catheter ablation (CA) can improve exercise tolerance and quality of life (QOL) in patients with atrial fibrillation (AF). However, its differential effects on muscle strength between paroxysmal AF (PAF) nonparoxysmal (Non‐PAF) remain unclear. Methods We evaluated 94 (67.8 ± 10.3 years old, 71% male) who underwent CA (PAF/Non‐PAF 46/48) without recurrence. Six‐minute walk distance (6MWD), leg strength, an AF‐specific QOL questionnaire (AFQLQ) were at baseline, 3, 6 months...
Background: Diagnosis of bone metastases would be hastened if they could detected on plain radiographs obtained at the first visit to an orthopedic surgeon. However, lesions are often undetectable radiography. Bone metastasis is diagnosed in only a few patients, and diagnosis delayed many cases. We investigated diagnostic performance radiography that used new image processing method, Dynamic Visualization II (DV), diagnose metastases. Methods: enrolled 29 patients with symptomatic pelvic who...
Osteoporosis-related fragility fractures such as proximal femoral and vertebral are associated with decreased activities of daily living a shorter life span. Many persons osteoporosis do not receive testing or treatment. Introducing fracture liaison services (FLSs) to hospitals is an effective approach for reducing this treatment gap. Understanding interest in among nurses physicians, their knowledge osteoporosis, thoughts on team medicine might be helpful when implementing FLSs. An FLS had...
A triptycene-based shape-persistent belt-shaped macrocycle, metallonanobelt, was synthesized by the self-assembly of 2,3,6,7-tetraaminotriptycene L and square planar Pd2+. The pentamer selectively formed complexation with Pd2+ in presence pillar[6]arene derivative P6 having triethylene glycol pendant as a template, whereas mixture trimer, tetramer, obtained absence template. successfully isolated based on solubility difference between metallonanobelt It also revealed that remarkably stable...
Local impedance (LI) can indirectly measure catheter contact and tissue temperature during radiofrequency ablation (RFCA). However, data on the effects of angle LI parameters are scarce. This study aimed to evaluate influence changes lesion size with two different LI-sensing catheters in a porcine experimental study.Lesions were created by INTELLANAV MiFi™ OI (MiFi) STABLEPOINT™ (STABLEPOINT). RFCA was performed 30 W duration s. The force (CF) (0, 5, 10, 20, g) (30°, 45°, 90°) changed each...
The aim was to investigate oxygen metabolism of the hypertrophic right ventricle in anaesthetised open chest dogs.Right ventricular hypertrophy induced by pressure overload with banding pulmonary artery for six months. Coronary blood flow and myocardial were determined during control after increasing consumption, compared those normal left ventricles.Seven mongrel dogs 21 used. All pentobarbitone sodium.Oxygen extraction [(A-V)O2] myocardium greater than that controls almost identical...
Abstract Background Although the lesion size index (LSI) has been well established, it is sometimes difficult to achieve first‐pass pulmonary vein isolation (PVI) and avoid acute reconnections, even with LSI‐guided procedures. The purpose of this study was assess predictive accuracy a novel parameter, optimized (o‐LSI), perform PVI. Methods voltage maps created by Advisor™ high‐density (HD) grid catheter before PVI in 35 atrial fibrillation (AF) patients were examined for an association...
Background:The incidence of new-onset atrial high-rate episode (AHRE) is higher among patients with cardiac implantable electronic devices (CIEDs) than in the general population. We sought to elucidate clinical factors associated AHRE CIED patients, including P-wave dispersion (PWD) sinus rhythm.
We prospectively collected device and heart rate data through remote monitoring (RM) of patients with an implantable cardioverter defibrillator (ICD). The objective was to identify the predictors lethal arrhythmic events (VT/VF).Thirty-three (mean age: 50 years) ICDs [with functionality variability (HRV) analysis] were divided into two groups [VT/VF (+), VT/VF (-) ]. Clinical, (ventricular lead impedance; amplitude ventricular electrogram), HRV compared between groups. NN interval-index...
Abstract Background Previous studies have identified noninvasive methods for predicting atrial fibrillation (AF) recurrence after catheter ablation (CA). We assessed the association between AF and late potentials (ALPs), which were measured using P‐wave signal‐averaged electrocardiography (P‐SAECG). Methods Consecutive patients with paroxysmal who underwent their first CA at our institution August 2015 2019 enrolled. P‐SAECG was performed before CA. Two ALP parameters evaluated:...
of patients at high risk for lethal arrhythmia, that is, ventricular tachycardia (VT) and fibrillation (VF). 7Indications WCD in Japan are as follows: 8-10 (1) ≤40 days after the onset acute myocardial infarction (AMI) with left ejection fraction (LVEF) ≤35% heart failure (HF) symptoms New York Heart Association (NYHA) class II or III; (2) LVEF ≤90 coronary artery bypass, NYHA III HF during percutaneous intervention (PCI); (3) non-ischemic onset; (4) irreversible severe satisfying transplant...
Introduction: Few non-invasive parameters have been identified for predicting atrial fibrillation (AF) recurrence after catheter ablation (CA). This study aimed to assess the association between AF and late potentials (ALP) measured using P-wave signal-averaged electrocardiography (P-SAECG). Methods results: Consecutive patients with paroxysmal who underwent first CA at our institution August 2015 2019 were enrolled. P-SAECG was performed before CA. Two ALP evaluated: root mean square...