A5087950314- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- Pain Mechanisms and Treatments
- Dental materials and restorations
- Botulinum Toxin and Related Neurological Disorders
- Bone Tissue Engineering Materials
- Dental Health and Care Utilization
- Myofascial pain diagnosis and treatment
- Periodontal Regeneration and Treatments
- Heart Rate Variability and Autonomic Control
- Infrared Thermography in Medicine
- Dysphagia Assessment and Management
- Orthopaedic implants and arthroplasty
- Obstructive Sleep Apnea Research
- Nutrition and Health in Aging
- Dental Radiography and Imaging
- Dental Anxiety and Anesthesia Techniques
- Voice and Speech Disorders
- Musculoskeletal pain and rehabilitation
- Oral and gingival health research
- Laser Applications in Dentistry and Medicine
- Advanced MRI Techniques and Applications
- Trigeminal Neuralgia and Treatments
- Cardiac Imaging and Diagnostics
- Dental Research and COVID-19
Okayama University
2014-2024
Osaka Dental University
2022-2024
Okayama University Hospital
2005-2022
Japan Society for the Promotion of Science
2020-2022
Pharmaceutical Biotechnology (Czechia)
2015-2021
University of Dental Medicine
1995-2013
Sapporo Medical University
2009
Shirasagi Hospital
2008
St. John's School
2005
University of Southern California
2005
The common methods for treating anterior disk displacement without reduction (ADDwor) are not based on randomized controlled clinical trials. Our study evaluated non-surgical treatments in 69 MRI-confirmed ADDwor subjects (m/f = 6/63). Subjects were randomly assigned to a control group and one of two treatment groups. Outcomes included maximum mouth opening, visual analogue scale pain, daily activity limitation. Calibrated examiners collected data at the initial interview 0, 2, 4, 8 weeks...
Aim Previous studies on the association between intraoral conditions and mortality in community‐dwelling older individuals reported that fewer present teeth (PT) are significant risk factors for mortality. However, how number of PT relative to functional (FT), including both rehabilitated teeth, influences has not been investigated fully. This study examined impact FT among Japanese adults. Methods was a retrospective, observational population‐based follow‐up study, which 1188 who...
Bone marrow–derived mesenchymal stem/progenitor cells (BMSCs) are commonly used in regeneration therapy. The current primary source of BMSCs is the iliac crest; however, procedure associated with various burdens on patient, including risk pain and infection. Hence, possibility to collect from other, more accessible, sources would be an attractive approach. It well known that stem migrate surrounding tissues play important roles wound healing. We thus hypothesized could isolated granulation...
Purpose The purpose of the study was to compare long-term performance three prostheses for partial edentulism: implant-supported, fixed denture (IFD), (FPD), and removable (RPD), in terms prosthesis survival oral health-related quality life (OHRQoL).
Bone morphogenetic protein-2 (BMP-2) and fibroblast growth factor-2 (FGF-2) have been regarded as the major cytokines promoting bone formation, however, several studies reported unexpected results with failure of formation or resorption these factors. In this study, BMP-2 FGF-2 adsorbed into atellocollagen sponges were transplanted defects in marrow-scarce calvaria (extramedullary environment) marrow-abundant femur (medullary for analysis their vivo effects not only on osteoblasts,...
Summary This retrospective study identified the risk factors for fracture of veneering materials and screw loosening implant‐supported fixed partial dentures in partially edentulous cases. The group included a total 182 patients who were installed 219 suprastructures at F ixed P rosthodontic C linic O kayama U niversity D ental H ospital between ebruary 1990 M arch 2005 subdivided two subgroups: 120 (149 facing suprastructures) subgroup to investigate materials, 81 (92 identify abutment...
Abstract Keratinized mucosa is of fundamental importance to maintain healthy gingival tissue, and understanding the mechanisms oral keratinization crucial successfully manage gingiva. Previous studies have shown a strong involvement basement membrane in proliferation differentiation epithelial cells. Therefore, first, identify keratinized mucosa-specific components, immunohistochemical analysis for six alpha chains type IV collagen was performed 8-week-old mice. No difference expression...
In a previous study, we successfully coated hydroxyapatite (HAp) onto titanium (Ti) plates using the erbium-doped yttrium aluminum garnet pulsed-laser deposition (Er:YAG-PLD) method. this performed further experiments to validate in vitro osteogenic properties, macrophage polarization, and vivo osseointegration activity of HAp-coated Ti (HAp-Ti) screws. Briefly, HAp film surfaces screws via Er:YAG-PLD. The surface morphological, elemental, crystallographic analyses confirmed successful...
Recent studies have shown that infraorbital nerve constriction (IoNC)-induced mechanical allodynia has been attenuated by administration of highly purified 150-kDa Botulinum neurotoxin type A (BoNT/A). Here, we extend these to determine whether BoNT/A could attenuate IoNC-induced symptoms thermal hyperalgesia. Instead testing head withdrawal thresholds, a operant assay was used evaluate cortical processing sensory input following IoNC. In this assay, fasted rat's desire obtain food reward...
This study aimed to compare the survival rates of remaining teeth between implant-supported fixed dentures (IFDs) and removable partial (RPDs) in patients with large edentulous cases. The second goal was assess risk factors for tooth loss. subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital their space exceeding least four continuous missing teeth. Twenty-one included IFD group 82 RPD group. Survival calculated three subcategories:...
To investigate the role of endothelium-derived nitric oxide (EDNO) and adenosine in functional myocardial hyperemia, we examined effect NG-nitro-L-arginine (L-NNA) 8-p-sulfophenyltheophylline (8-SPT) on coronary vasodilation response to increased oxygen consumption pentobarbital sodium-anesthetized dogs. L-NNA significantly attenuated increase conductance from 28 +/- 6 16 2% with atrial pacing, 69 5 36 6% isoproterenol, 25 9 4% constriction aorta. 8-SPT given alone same extent as L-NNA. The...
To compare the complication rate of natural teeth adjacent to implant supported dentures (IFDs) with that serving as abutments for fixed partial (FPDs). The second goal was assess risk factors complications in bounded edentulous spaces.The study subjects were selected from patients who received prosthodontic treatment their space not exceeding two missing between February 1990 and March 2007. Sixty-one included IFD group 66 FPD group. Tooth defined tooth extraction, periodontal lesion,...
Objectives To identify significant risk factors associated with incidence of mortality and pneumonia in whole‐community‐based older inpatients resident Japanese rural region. Methods Patients than 65 years admitted between 1 April 15 2010 to a core hospital located region were exhaustively recruited, during the 32‐month follow‐up period evaluated. Independent variables at baseline measurement included age, gender, body mass index, Charlson comorbidity functional dependency, oral self‐care...
The aim of this study was to evaluate the effect treating titanium (Ti) with polyphosphoric acid on attachment and proliferation human bone marrow derived mesenchymal stem cells (hBMSCs). Cleaned Ti disks were immersed into three different concentrations solution (0.1, 1, 10 wt %) % orthophosphoric for 24 h at 37 degrees C. in distilled water C served as control. level that interacted surface determined by measuring P/Ti ratio (atom%/atom%) using X-ray photoelectron spectroscopy. Degrees...
This educational trial was an eight-day problem-based learning (PBL) course for fourth-year predoctoral students at Okayama University's dental school who interviewed elderly residents living in a nursing home. The purpose of this PBL to introduce geriatric dentistry the by allowing them, independently, discover clinical problems patients as well solutions. sixty-five were divided into nine small groups and received patient information (age, gender, degree care needed, medical history, food...