A5026706248- Dysphagia Assessment and Management
- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Pediatric health and respiratory diseases
- Dental Implant Techniques and Outcomes
- Nosocomial Infections in ICU
- Salivary Gland Disorders and Functions
- Temporomandibular Joint Disorders
- Voice and Speech Disorders
- Nutrition and Health in Aging
- Frailty in Older Adults
- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Dental Erosion and Treatment
- Immune Response and Inflammation
- Legionella and Acanthamoeba research
- Child Nutrition and Feeding Issues
- HIV/AIDS oral health manifestations
- Dental Research and COVID-19
- Exercise and Physiological Responses
- Oral and Maxillofacial Pathology
- Orthodontics and Dentofacial Orthopedics
- Obstructive Sleep Apnea Research
- Periodontal Regeneration and Treatments
- Cleft Lip and Palate Research
Tokyo Dental College
2014-2024
Japan Society for the Promotion of Science
2020-2022
LMU Klinikum
2011
Ludwig-Maximilians-Universität München
2011
Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation
2011
Aim Previous studies on the association between intraoral conditions and mortality in community‐dwelling older individuals reported that fewer present teeth (PT) are significant risk factors for mortality. However, how number of PT relative to functional (FT), including both rehabilitated teeth, influences has not been investigated fully. This study examined impact FT among Japanese adults. Methods was a retrospective, observational population‐based follow‐up study, which 1188 who...
Summary The purpose of this study was to clarify which oral environmental factors affected number microbes in saliva an edentulous environment. We enrolled 68 subjects the study. Numbers total anaerobic bacteria and Candida species were determined. Age, sex, un‐stimulated salivary flow rate, pH viscosity saliva, histatin level tongue coating status, pressure, denture plaque material base, duration edentulism, frequency self health care cigarettes per day also investigated as factors....
doi: 10.1111/j.1741‐2358.2011.00506.x Colonisation of the oral cavity by periodontopathic bacteria in complete denture wearers Objective: The purpose this study was to investigate colonisation and sites elderly upper lower wearers. We also investigated relationship between level hygiene bacteria. Materials methods: Forty edentulous 37 dentate volunteers participated study. Samples were collected from whole saliva, levels Aggregatibacter actinomycetemcomitans , Prevotella intermedia...
<h3>Objectives</h3> Interleukin-1 receptor-associated kinase (IRAK)-M suppresses Toll-like receptor (TLR)-mediated activation of innate immunity during infection. A similar role was hypothesised for IRAK-M in autoimmunity. <h3>Methods</h3> Irak-m-deficient mice were crossed with autoimmune C57BL/6-lpr/lpr and detailed phenotype analysis performed. <h3>Results</h3> Irak-m deficiency converted the mild into a massive lymphoproliferative syndrome lethal lung disease lupus nephritis. induced...
Abstract Objectives Lip‐seal strength, which represents the muscle strength of lips, appears to chiefly contribute mastication and pronunciation. However, functional characteristics lip‐seal in adults are still undefined. The present study aimed understand not only distribution adult men women but also effect age on this identify oral motor functions correlated with strength. Materials methods subjects included 339 participants (men: 170, 39.2 ± 18.2 years; women: 169, 43.1 19.7 years). Oral...
Aim To evaluate the effect of oral cleaning using a mouthwash and mouth moisturizing gel on number bacteria moisture level tongue surface older adults requiring nursing care. Methods The 60 participants were randomly divided into groups according to their use procedures as follows: group 1, ( M + m); 2, (M); 3, water W 4, ). anaerobic bacteria, coating index measured at baseline, after 1 2 weeks commenced compare effectiveness among groups. Results There was no significant difference in...
Systemic lupus erythematosus (SLE) is still treated with global immunosuppressants serious toxicities. We hypothesized that endogenous immunosuppressive molecules might be able to control SLE manifestations more specifically. Heat shock protein 10, or chaperonin 10 (Cpn10), a secretory molecule can suppress innate and adaptive immunity. Recombinant human Cpn10 (100 μg per mouse) was given intraperitoneally healthy-appearing female MRL-(Fas)lpr mice from 12 22 weeks of age. At the age weeks,...
Aggregatibactor actinomycetemcomitans colonizes human periodontal lesions and is implicated in both aggressive periodontitis chronic periodontitis. Clinical isolated colonies of A. were rough type. The type has a remarkable ability to adhere tenaciously solid surfaces colonize firmly. Rough change into smooth during the course repeated inoculation biofilm-forming activity ceases. Adherence by mediated tight-adherence (tad) gene locus, which includes flp, rcpA rcpB. In this study, we...
To examine the relationship between number of present and functional teeth at baseline future incidence loss independence.Participants were community-dwelling older individuals who participated in a comprehensive geriatric health examination conducted Kusatsu town, Japan, 2009 2015. The primary endpoint was independence among participants, defined as first certification long-term care insurance Japan. numbers determined via an oral examination. Demographics, clinical variables (e.g., history...
ABSTRACT Objective This study aimed to examine the effects of an oral hypofunction management protocol incorporating function training and provision dietary advice for 3 months on nutritional status older patients diagnosed with hypofunction. Background Oral is associated poor status, emphasising need protocols guidance advice. However, efficacy such remains unclear. Materials Methods quasi‐randomised controlled clinical trial included 80 (age ≥ 65 years) who were divided into two groups...
The tongue surface in older people requiring nursing care is often coated with a layer believed to comprise, keratinized products of degeneration, food residue, bacteria, and leukocytes attached the papillae. Which factors affect status this coating remain be elucidated, however. purpose study was evaluate related care. participants comprised 41 individuals admitted special homes for elderly. After undergoing tooth brushing cleaning by facility staff, were required refrain from oral until...
Aim The purpose of the present study was to evaluate application possibility water containing organic acids ( WOA ), made by some used as food additives, for chemical denture cleaning older adults microbial investigation. Methods Using an in vitro biofilm study, we determined effects on S treptococcus sanguinis , . pneumoniae and C andida albicans attached heat‐cured acrylic resins. Specimens were divided into three groups follows: control group TW commercial cleaner DC ) ). treated with...
This study investigated decline in oral function healthy young adults and compared it with that observed an earlier studies employing older adults. The participants comprised 130 (mean age 24.1±2.9 yr), all complete dentition. All underwent the hypofunction test established by Japanese Society of Gerodontology, which evaluates hygiene, dryness, occlusal force, tongue-lip motor (oral diadochokinetic rate; ODK), tongue pressure, masticatory swallowing function. average value for rate each...
The purpose of this study was to investigate time-dependent change in the number microbes on tongue surface after cleaning using a mouthwash or mouth moisturising gel for elders fed with feeding tube and care needs.Twelve through needs participated prospective crossover study. There were four kinds modes as follows: (i) mouthwash; (ii) gel; (iii) water; (iv) no negative control. total measured rapid oral bacteria detection device at baseline, immediately cleaning, 1, 3 5 hours evaluate each...
The objective of this study was to investigate the effect an interprofessional oral hygiene support program for elderly inpatients and perception caregivers towards health care.Participants comprised 37 requiring nursing care (17 males, 20 females; mean age, 83.3 ± 4.9 years) 29 registered nurses who participated in as a caregiver (4 25 45.2 10.3 years). In program, received daily cleaning by based on each patient's plan. number microbes tongue surface measured once week 12 weeks....
Lip-seal strength is important for articulating bilabials, capturing food during eating, maintaining fluid within the oral cavity before swallowing, and achieving swallowing pressure. The objective of this study was to investigate effect lip-seal resistance training on in young adults. participants comprised 15 healthy adults aged 26–34 years, all with complete dentition. Each required perform 5 weekdays a week 4 weeks commercially available instrument that purpose. placed midline, left...
The objective of this study was to determine the size residual ridge in edentulous elderly Japanese persons for preparation stock trays and clarify any correlations among items measured. participants comprised 74 patients requesting construction a complete denture maxilla, mandible, or both. length, width, anterior posterior height maxillary mandibular measured on prepared working model using caliper. For each ridges, measurement were analyzed employing Pearson's correlation coefficient. In...
Abstract Objectives Chewing increases frontal lobe activity, resulting in improved memory, learning ability, and response reaction time. This study aimed to assess the effects of elastic oral appliance chewing on activities functions lobe. Methods The participants were 15 healthy men with full dentulous (mean age, 27.4 ± 4.1 years). A prospective crossover design was used functions. Changes measured near‐infrared spectroscopy (NIRS). At baseline, assessed resting state. channels #7,...
Aim The purpose of the present study was to clarify relationship between frequency oral and denture cleaning personality in edentulous older adults. Methods Participants were 54 adults using maxillary mandibular complete dentures without any problems. A questionnaire used establish mechanical a brush. survey carried out based on E ysenck's factors introversion/extroversion emotional stability/instability. Stepwise logistic regression analyses identify which characteristic significantly...
症例の概要：患者は82 歳の女性．上下顎無歯顎で上顎骨左半側に網目状の複雑な欠損腔を有し，義歯は維持，安定不良であった．顎義歯新製にあたり，各個トレーを用いて精密印象採得し，試適後には咬合圧印象を行った．また義歯製作と並行して構音訓練を行った．考察：各個トレーを用いた精密印象および咬合圧印象により欠損腔内のアンダーカットを有効に利用し機能的な形態を義歯に付与できた．また義歯製作と並行して構音訓練を行ったことで早期に障害の改善が認められたと考えられる．結論：複雑な欠損腔を有する上顎顎欠損症例に対し欠損腔内のアンダーカットを利用し義歯の維持を向上させた．また構音訓練を並行して行いQOL を向上させた．
The aim of this study was to investigate the effects combining mechanical (ultrasonic) and chemical cleaning (using denture cleaners) on surface roughness silicone or acrylic soft relining materials. material with lowest Shore A hardness a routinely used in Japan were selected. Four groups established based type treatment: immersion water (W); ultrasonic tap (U); hypochlorous acid cleanser (HU); an acidic (AU). Following tests, determined as arithmetic mean height (Sa) maximum (Sz). Data...