- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- EEG and Brain-Computer Interfaces
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Non-Invasive Vital Sign Monitoring
- Moyamoya disease diagnosis and treatment
- Sympathectomy and Hyperhidrosis Treatments
- Peptidase Inhibition and Analysis
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Chromatin Remodeling and Cancer
- Nausea and vomiting management
- Cardiac Structural Anomalies and Repair
- Diabetes Treatment and Management
- Immune Cell Function and Interaction
- Parkinson's Disease Mechanisms and Treatments
- Neurological Complications and Syndromes
Kitasato University
2018-2025
Palmetto Hematology Oncology
2022
Gifu Municipal Hospital
2017
Nagoya Ekisaikai Hospital
2007
Background Recent clinical trials have demonstrated the possible pleiotropic effects of SGLT2 (sodium-glucose cotransporter 2) inhibitors in cardiovascular diseases. Atrial electrical and structural remodeling is important as an atrial fibrillation (AF) substrate. Methods Results The present study assessed effect canagliflozin (CAN), inhibitor, on a canine AF model. included 12 beagle dogs, with 10 receiving continuous rapid pacing 2 acting nonpacing group. dogs that received for 3 weeks...
Abstract Background Impact of baseline‐pool local impedance (BP‐LI) on the lesion size remains unclear. Methods Lesion in porcine left ventricular myocardium was evaluated using STABLEPOINT™ catheter across various ablation settings and BP‐LIs (100, 140, 180 ohms). Results A total 184 lesions were created with different durations (15/30/60 s) at 30 watts or powers (30/40/50 W) for 15 s. depth became deeper (2.8/3.0/3.6 mm s; p = .007, 4.0/4.9/4.6 .004, 5.9/5.5/5.2 60 .710) width wider...
The relationship between atrial high-rate episode (AHRE) burden (i.e., the frequency of tachyarrhythmia) and heart failure (HF) risk is unclear. We hypothesized that new-onset higher AHRE are associated with HF.
Abstract Background Although the lesion size index (LSI) has been well established, it is sometimes difficult to achieve first‐pass pulmonary vein isolation (PVI) and avoid acute reconnections, even with LSI‐guided procedures. The purpose of this study was assess predictive accuracy a novel parameter, optimized (o‐LSI), perform PVI. Methods voltage maps created by Advisor™ high‐density (HD) grid catheter before PVI in 35 atrial fibrillation (AF) patients were examined for an association...
Background:The incidence of new-onset atrial high-rate episode (AHRE) is higher among patients with cardiac implantable electronic devices (CIEDs) than in the general population. We sought to elucidate clinical factors associated AHRE CIED patients, including P-wave dispersion (PWD) sinus rhythm.
We prospectively collected device and heart rate data through remote monitoring (RM) of patients with an implantable cardioverter defibrillator (ICD). The objective was to identify the predictors lethal arrhythmic events (VT/VF).Thirty-three (mean age: 50 years) ICDs [with functionality variability (HRV) analysis] were divided into two groups [VT/VF (+), VT/VF (-) ]. Clinical, (ventricular lead impedance; amplitude ventricular electrogram), HRV compared between groups. NN interval-index...
Abstract Background Previous studies have identified noninvasive methods for predicting atrial fibrillation (AF) recurrence after catheter ablation (CA). We assessed the association between AF and late potentials (ALPs), which were measured using P‐wave signal‐averaged electrocardiography (P‐SAECG). Methods Consecutive patients with paroxysmal who underwent their first CA at our institution August 2015 2019 enrolled. P‐SAECG was performed before CA. Two ALP parameters evaluated:...
Optimal antithrombotic strategy for atrial fibrillation (AF) patients with a history of percutaneous coronary intervention (PCI) has been under debate. The actual prescription trend therapy these remains unclear, especially in chronic phase.Patients AF having at least 1-year PCI were retrospectively evaluated 2010, 2012, 2014, and 2016. A total 266 finally enrolled this study. proportion prescribed oral anticoagulants (OACs) gradually increased over the study period (56%, 67%, 73%, 74% 2016,...
Esophageal injury is a major concern during catheter ablation of atrial fibrillation. Operators avoid radiofrequency applications on the esophagus by changing line; however, it unavoidable in patients with dilated esophagus, such as esophageal achalasia. Steerable thermometer useful for evaluating precise temperatures to prevent injury.
of patients at high risk for lethal arrhythmia, that is, ventricular tachycardia (VT) and fibrillation (VF). 7Indications WCD in Japan are as follows: 8-10 (1) ≤40 days after the onset acute myocardial infarction (AMI) with left ejection fraction (LVEF) ≤35% heart failure (HF) symptoms New York Heart Association (NYHA) class II or III; (2) LVEF ≤90 coronary artery bypass, NYHA III HF during percutaneous intervention (PCI); (3) non-ischemic onset; (4) irreversible severe satisfying transplant...
Introduction: Few non-invasive parameters have been identified for predicting atrial fibrillation (AF) recurrence after catheter ablation (CA). This study aimed to assess the association between AF and late potentials (ALP) measured using P-wave signal-averaged electrocardiography (P-SAECG). Methods results: Consecutive patients with paroxysmal who underwent first CA at our institution August 2015 2019 were enrolled. P-SAECG was performed before CA. Two ALP evaluated: root mean square...
Background: The DiamondTemp TM (DT) catheter enables precise temperature-controlled ablation. However, the DT lacks contact force measurement capabilities. This study investigated impact of angle on relationship between and local impedance change in a porcine experimental model. Hypothesis: We hypothesized that correlation would differ different angles catheter. Aims: To evaluate (30°, 45°, 90°) change. Methods: used freshly sacrificed hearts set them circulated water pool. (5, 10, 30 grams)...
Abstract Background We prospectively collected device and heart rate data, i.e. variability (HRV), through remote monitoring (RM) of patients with implantable cardioverter defibrillator (ICD). Several studies have demonstrated usefulness RM in implanted patients, however, reports concerning the predictors lethal ventricular arrhythmias are limited. Purpose The objective was to identify arrhythmic events (VT/VF). Methods Thirty-three (mean age: 50 years) ICDs [with functionality HRV analysis]...
Abstract Background Right ventricular (RV) pacing causes left (LV) dyssynchrony sometimes resulting in pacing‐induced cardiomyopathy. However, RV for hypertrophic obstructive cardiomyopathy is one of the treatment options. LV flow energy loss (EL) using vector mapping (VFM) a novel hemodynamic index assessing cardiac function. Our study aimed to elucidate impact on EL normal function and (HCM) patients. Methods A total 36 patients with dual‐chamber pacemakers sick sinus syndrome or...