A5087789904- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Retinopathy of Prematurity Studies
- Birth, Development, and Health
- Mitochondrial Function and Pathology
- Epigenetics and DNA Methylation
- Mosquito-borne diseases and control
- Vector-borne infectious diseases
- Insect and Pesticide Research
- Preterm Birth and Chorioamnionitis
- Neonatal and Maternal Infections
- Infant Development and Preterm Care
- Pulmonary Hypertension Research and Treatments
Telemark Hospital
2023
Oslo University Hospital
2017-2020
University of Oslo
2017-2019
<b><i>Background:</i></b> Bronchopulmonary dysplasia (BPD) is a common cause of abrupted lung development after preterm birth. BPD may lead to increased rehospitalization, more severe and frequent respiratory infections, life-long reduced function. The gene regulation in lungs with complex, various genetic epigenetic factors involved. <b><i>Objectives:</i></b> aim this study was examine the regulatory relation between expression epigenome (DNA...
In this study, we aimed to analyze differences in plasma protein abundances between infants with and without bronchopulmonary dysplasia (BPD), add new insights into a better understanding of the pathogenesis disease. Cord peripheral blood neonates (≤ 30 weeks gestational age) was drawn at birth 36th postmenstrual week (36 PMA), respectively. Blood samples were retrospectively subdivided BPD(+) BPD(−) groups, according development BPD. Children BPD characterized by decreased afamin, gelsolin...
Mikrobiologisk avdeling Sykehuset
Purpose: Retinopathy of prematurity (ROP) is a vision-threatening complication premature birth, in which the etiology still remains unclear. Importantly, molecular processes that govern these effects can be investigated perturbed plasma proteome composition. Thus, proteomics may add new insights into better understanding pathogenesis this disease. Methods: The cord and peripheral blood neonates (≤30 weeks gestational age) was drawn at birth 36th postmenstrual week (PMA), respectively. Blood...
Abstract Background We aimed to identify global blood and retinal gene expression patterns in murine oxygen-induced retinopathy (OIR), a common model of prematurity, which may allow better understanding the pathogenesis this severe ocular prematurity complication identification potential biomarkers. Methods A total 120 C57BL/6J mice were randomly divided into an OIR group, 7-day-old pups maintained 75% oxygen for 5 days, or control group. RNA was extracted from whole-blood mononuclear cells...
Objective: To examine the gene expression regarding pulmonary vascular disease in experimental bronchopulmonary dysplasia young mice. Premature delivery puts babies at risk of severe complications. Bronchopulmonary (BPD) is a common complication premature birth leading to lifelong affection function. BPD recognized as arrested alveolar development. The process not fully described and no complete cure or prevention known. focus interest search for treatment has traditionally been airspace...
Objectives: Evaluate the time dependent expression of genes in preterm neonates and verify influence ontogenic maturation environmental factors on gene after birth. Material methods: The study was carried out 20 full-term newborns 62 (mean birth weight = 1002 [g] (SD: 247), mean gestational age 27.2 weeks 1.9)). Blood samples were drawn from all participants at 36th week postmenstrual group to assess whole genome umbilical cord blood peripheral leukocytes, respectively. (SurePrint G3 Human...