A5038633848- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- interferon and immune responses
- Antimicrobial Peptides and Activities
- CRISPR and Genetic Engineering
- Neurobiology and Insect Physiology Research
- Aquaculture Nutrition and Growth
- Genetic Mapping and Diversity in Plants and Animals
- Peroxisome Proliferator-Activated Receptors
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Physiological and biochemical adaptations
- Zebrafish Biomedical Research Applications
- Immune Response and Inflammation
- Insect Resistance and Genetics
- Lipid metabolism and biosynthesis
- Microbial Community Ecology and Physiology
- Machine Learning in Bioinformatics
- Marine Bivalve and Aquaculture Studies
- Folate and B Vitamins Research
- Plant biochemistry and biosynthesis
- Nicotinic Acetylcholine Receptors Study
- Reproductive biology and impacts on aquatic species
- Water Quality Monitoring Technologies
- Macrophage Migration Inhibitory Factor
Hohai University
2019-2025
Chinese Academy of Sciences
2021-2023
Institute of Hydrobiology
2023
University of Oslo
2016-2021
University of Stirling
2020-2021
South China Sea Institute Of Oceanology
2021
Institute of Oceanology
2021
East China Normal University
2010-2019
Central South University
2016
Second Xiangya Hospital of Central South University
2016
Whey acidic proteins (WAP) belong to a large gene family of antibacterial peptides, which are critical in the host immune response against microbial invasion. The common feature these is single WAP domain maintained by at least one four-disulfide core (4-DSC) structure rich cysteine residues. In this study, double (DWD)-containing protein, Es-DWD1, was first cloned from Chinese mitten crab (Eriocheir sinensis). full-length Es-DWD1cDNA 1193 bp, including 411 bp open reading frame (ORF)...
Pattern recognition receptors (PPRs) are part of the initial step a host defense against pathogens in detecting pathogen-associated molecular patterns. However, determinants specificity this by innate immune molecules invertebrates remain largely unknown. In study, we investigated potential involvement an invertebrate PRR C-type lectin antimicrobial response crustacean Eriocheir sinensis. Based on expressed sequence tags (EST) hepatopancreatic cDNA library, full-length EsLecF was cloned and...
The pathogenesis of borderline personality disorder (BPD) is not well understood. We examined the microstructure white matter in patients with BPD.Treatment-naïve young adult BPD (N = 30) and young-adult healthy controls (HCs; N 31) were subjected diffusion tensor imaging (DTI). Microstructural parameters analyzed via tract-based spatial statistics (TBSS) post hoc tractography.TBSS analysis revealed that, relative to HC group, group had significantly lower fractional anisotropy (FA) values...
Invertebrates rely solely on the innate immune system for defense against pathogens and other stimuli. Fatty acid binding proteins (FABP), members of lipid superfamily, play a crucial role in fatty transport metabolism are also involved gene expression induced by acids. In vertebrate system, FABP is inflammation regulated acids through its interaction with peroxidase proliferator activate receptors (PPARs). However, functions invertebrates not well characterized. For this reason, we...
Down syndrome cell adhesion molecule (Dscam) generates tens of thousands isoforms by alternative splicing, thereby providing crucial functions during immune responses. In this study, a novel Dscam signaling pathway was investigated in crab, which remains poorly characterized invertebrates. Bacterial infection induced the cytoplasmic cleavage intracellular domains (ICDs) γ-secretase, and then released ICDs carrying specific alternatively spliced exons could directly interact with IPO5 to...
Abstract Background Consistent individual differences in behaviour, known as animal personalities, have been demonstrated within and across species. In fish, studies applying an personality approach used to resolve variation physiological molecular data suggesting a linkage, genotype-phenotype, between behaviour transcriptome regulation. this study, using three fish species (zebrafish; Danio rerio , Atlantic salmon; Salmo salar European sea bass; Dicentrarchus labrax ), we firstly address...
In order to determine the minimal dietary zinc (Zn) requirements in Chinese mitten crab, Eriocheir sinensis, we assessed influence of Zn levels on weight gain, survival, fatty acid composition, expressions acid-binding protein (FABP) and metallothionein-1 (MT-1) transcripts at end an 8-week feeding regime. Supplemental (0, 10, 20, 40 80 mg kg−1 diet) was administered orally crabs via diet. The results indicate that supplementation 20 diet yielded largest gain. While hepatopancreatic...