A5062345051- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Medical Research and Treatments
- Cancer Cells and Metastasis
- Cancer-related molecular mechanisms research
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Colorectal and Anal Carcinomas
- Esophageal and GI Pathology
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Management of metastatic bone disease
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic factors in colorectal cancer
- Effects of Radiation Exposure
- 3D Printing in Biomedical Research
- Liver Disease and Transplantation
- Endometrial and Cervical Cancer Treatments
- Colorectal Cancer Treatments and Studies
- Cancer Research and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Oral health in cancer treatment
Shantou Central Hospital
2011-2020
Sun Yat-sen University
2013-2018
The impact of sex on prognosis patients with esophageal squamous cell cancer (ESCC) who underwent definitive radiotherapy remained unclear. present study aimed to determine the ESCC radiotherapy.Between January 2009 and December 2015, in Shantou Central Hospital were included this study. Progression-free survival (PFS) overall (OS) rates estimated using Kaplan-Meier method. PFS OS compared between female male patients. Cox regression model was used identify prognostic factors. Propensity...
Background: This present study aimed to explore the prognostic value of pretreatment neutrophil and lactate dehydrogenase (LDH) develop a risk scoring model predict prognosis in esophageal squamous cell cancer (ESCC) patients treated with definitive radiotherapy. Methods: Retrospectively collected data who received radiotherapy for ESCC at Shantou Central Hospital between January 2009 December 2015 were included analysis. The association level LDH clinicopathological characteristics...
The aim of this work was to evaluate the prognostic value tumor length and diameter for patients with esophageal squamous cell cancer (ESCC) treated definitive (chemo)radiotherapy identify potential indicators separate nonsurgical T staging, which are needed in clinical practice.A total 682 ESCC who underwent between 2009 2015 were reviewed. Esophageal determined by barium esophagography computed tomography before treatment. Univariate multivariate analyses used assess impact on long-term...
To evaluate the efficacy and toxicity of hypofractionated stereotactic body radiotherapy (SBRT) for patients with recurrent or residual hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).Between June 2008 July 2015, thirty-three HCC were treated by SBRT. There 63 lesions in 33 patients. A total dose 39-45 Gy/3-5 fractions was delivered to 70-80% isodose line.Objective response rate (CR + PR) 84.8% at 6 months. The overall survival 87.9%, 75.8%, 57.6%, 45.5%...
The prognostic value of supra-clavicular lymph node (SCLN) metastases in esophageal cancer (EC) is still not clear. From January 2009 to December 2015, a survival analysis was performed retrospectively identify the SCLN metastasis on 751 patients with EC treated definitive chemo-radiotherapy (dCRT). median follow-up duration for living 56.6 months. overall (OS) all 16.6 Patients had much poorer prognosis OS (χ2 = 17.342, P < 0.001), distant metastasis-free (DMFS) 24.793, 0.001) and...
Abstract No current in vitro tumor model replicates a tumor’s vivo microenvironment. A culturing technique that better preserves pathophysiological conditions is needed for some important clinical applications, including personalized drug-sensitivity/resistance assays. In this study, we utilized autologous serum or body fluid to build 3D scaffold and grow patient’s tumor. We named “3D-ACM” (autologous culture method). Forty-five samples from biopsies, surgically removed tissues malignant...
Objective To evaluate the clinical features of nasopharyngeal carcinoma with different sur英文摘要>=rival time and to analyze factors associated prognosis improvement.Methods Three hundred fifty three patients treated in our hospital from January 2000 April 2002 were analyzed retrospectively.They divided into groups based on their survival time.One forty five A whose overall less than years.Sixteen included B group greater or equal years ten years,and other one ninety two C years.The compared...
Objective To evaluate the clinical features of local advanced glottic laryngeal cancer patients with beyond five years survival and to provide help for treatment patients.Methods The data 129 cases treated in our hospital from January 1999 August 2005 were analyzed retrospectively.They divided into two groups based on their time.Forty six included first group other eighty three second group.The compared factors associated identified.Results Compared under survival,the lymph node metastatic...
Objective To evaluate the efficacy and safety of induction chemotherapy three-dimensional conformal radiation (3D-CRT) combined with endostar in treatment locally advanced non-small cell lung cancer (NSCLC).Methods Thirty patients NSCLC were enrolled divided into observation group (15 cases) control cases).In group,the received 3D-CRT endostar.Chemotherapy:Vinorelbine 25mg/m2 on day 1 8,DDP 30mg/m2 2 to 4.Endostar 7.5mg/m2 14,which was used again after 7 days for 4 cycles.In at same...
Objective To evaluate the clinical efficacy of platinum-based chemotherapy combined radiotherapy for cervical cancer.Methods From October 2008 to June 2010,61 patients with cancer were treated by radiotherapy( conventional external radiation and after-loading brachytherapy,to a total dose 8000- 8500 cGy)combined (cisplatin or nedaplatin 20 mg/m2,one times per weeks) in our department.The side effects evaluated.Results Among 61 patients,the short-term effective rate was 100％ ( 61/61 ) 1-year...
Objective To evaluate the effects and toxic side-effects of radiotherapy combined with xeloda or carboplatin respectively for locally advanced esophagus carcinoma.Methods 74 cases carcinoma were randomly allocated into two groups.One group received Xeloda,500mg at a time,twice day,taken orally from beginning till end treatment.The second Carboplatin by intravenous drip 100mg day,for 5 days,from first week radiotherapy.Results The overall response rate in Xeloda was 91.4％ 89.7％ group.The...
Objective To explore an effective preventive measures for the oral mucosa reaction caused by chemo - radiotherapy.Methods A total of 100 cases patients with head and neck malignant tumor undergone radiation chemotherapy were randomly divided into two groups.The test group was treated human recombinant granulocyte macrophage colony stimulating factor ( rhGM CSF),and control placebo,accompanied health education holistic nursing care.Effectivity,pain relief safety CSF in treatment mucosal...
Objective To evaluate the clinical effectiveness and major toxic effect of radiotherapy combined with docetaxol cisplatin respectively in treatment locally advanced non-small cell lung cancer (NSCLC).Methods 98 patients NSCLC were randomly divided into two groups.All treated 3D-CRT.One group was docetaxel,20mg/m2,every week,totally 6 times.The other cisplatin,30mg/m2,every total dose 60 ～66Gy,2Gy/F,5 times each week for 5 ～7 weeks.The between groups compared.Results The median survival time...