A5102753780- Viral Infections and Immunology Research
- Aquaculture Nutrition and Growth
- MicroRNA in disease regulation
- Viral gastroenteritis research and epidemiology
- Cancer-related molecular mechanisms research
- Aquaculture disease management and microbiota
- Child Nutrition and Water Access
- Veterinary medicine and infectious diseases
- Mycobacterium research and diagnosis
- Animal Disease Management and Epidemiology
- Circular RNAs in diseases
- Tuberculosis Research and Epidemiology
- Viral Infections and Vectors
- Marine Bivalve and Aquaculture Studies
- Vector-Borne Animal Diseases
- Coccidia and coccidiosis research
- Cancer, Hypoxia, and Metabolism
- Heavy Metal Exposure and Toxicity
- Environmental Toxicology and Ecotoxicology
- Female Genital Mutilation/Cutting Issues
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Animal Nutrition and Physiology
- Urologic and reproductive health conditions
- Mercury impact and mitigation studies
- Eicosanoids and Hypertension Pharmacology
Chinese Academy of Fishery Sciences
2023-2025
Shaoxing People's Hospital
2015-2022
Zhejiang University
2017-2022
Shaoxing City Women and Children Hospital
2022
Yunnan Agricultural University
2016
Southwest University
2013
The Affiliated Yongchuan Hospital of Chongqing Medical University
2013
Chongqing Medical University
2013
China Tobacco
2011
The incidence of Ecytonucleospora hepatopenaei (EHP) infections in farmed shrimp has increased markedly recent years, resulting significant economic losses for the global farming industry. lack an efficacious drug EHP infection led to development a strategy based on timely screening and elimination EHP-carrying seeds as means preventing financial loss. This requires portable, accurate rapid detection methods EHP, especially when applied sites such farms. However, current user-friendly...
Cigarette smoking is the major risk factor for smoking-related interstitial fibrosis (SRIF). Despite recent advances, molecular mechanisms involved in initiation and progression of this disease remain elusive. We found 6 months chronic mainstream exposure induced SRIF C57 mice, which was associated with pronounced enhanced oxidative stress, bronchoalveolar inflammation but not apoptosis alveolar septal cell. used Affymetrix microRNA (miRNA) arrays to determine temporal alteration global gene...
Numerous efforts have been made to indentify reliable and predictive biomarkers detect the early signs of smoking-induced lung disease. Using 6-month cigarette smoking in mice, we established smoking-related interstitial fibrosis (SRIF). Microarray analyses cytokine/chemokine biomarker measurements were select circulating microRNAs (miRNAs) biomarkers. We demonstrated that specific miRNAs species (miR-125b-5p, miR-128, miR-30e, miR-20b) significantly changed, both tissue plasma, exhibited...
Aberrant angiogenesis in hepatocellular carcinoma (HCC) is associated with tumor growth, progression, and local or distant metastasis. Hypoxia-inducible factor 1α (HIF-1α) a transcription that plays major role regulating during adaptation of cells to nutrient-deprived microenvironments. Genetic defects Krebs cycle enzymes, such as succinate dehydrogenase fumarate hydratase, result elevation oncometabolites fumarate, thereby increasing HIF-1α stability activating the signaling pathway....
Severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV) infection, was first reported in 2010 China an initial fatality of up to 30%. The laboratory confirmation SFTSV infection terms detection viral RNA or antibody levels is critical for diagnosis and therapy. In this study, a new luciferase immunoprecipitation system (LIPS) assay based on pREN2 plasmid expressing NP gene tagged Renilla (Rluc), established used investigate the responses SFTSV. Totally 464 serum...
To describe the acceptability of male circumcision (MC) and explore potential factors associated with MC among rural-to-urban migrants in western China, a cross-sectional survey was conducted 1,904 subjects three provinces high HIV prevalence (Guangxi, Chongqing, Xinjiang) China between June 2009 November 2009. Through face-to-face interviews, participants completed self-administered questionnaire about demographics, knowledge, willingness reasons to accept or refuse MC, sexual behaviors,...
Human enterovirus 71 (EV-A71) is one of the main etiological agents hand, foot, and mouth disease (HFMD), which has been prevalent mainly in Asia-Pacific region past several decades. The nonstructural proteins EV-A71 will be expressed significantly during viral replication host cells after infection. For determination antibodies response against EV-A71, this study, complete 2ABC, 3ABC, 3D were Escherichia coli then studied for their immunoreactivity by immunoblot assay indirect enzyme-linked...
Enterovirus 71 (EV71) is a major cause of hand, foot and mouth disease (HFMD); however, no clinically approved vaccine or antiviral treatment currently available for EV71 infection. In the present study, murine model infection was constructed. The clinical isolates were amplified in Vero cells used to challenge adult mice via hydrodynamic injection (HI) intraperitoneal (IP). Following two challenges, >50% succumbed Surviving female identified have impaired fertility their litter sizes...