A5055966579- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Vascular anomalies and interventions
- Moyamoya disease diagnosis and treatment
- Coronary Artery Anomalies
- Neurosurgical Procedures and Complications
- Neurological Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Neurological Complications and Syndromes
- Catalysis and Oxidation Reactions
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Anatomy and Medical Technology
Research Center of Neurology
2023-2024
Meshalkin National Medical Research Center
2015-2023
Federal Medical-Biological Agency
2022-2023
Ministry of Health of the Russian Federation
2015-2022
Novosibirsk State Medical University
2015
Utilization of flow diverting devices is accompanied with dual antiplatelet therapy to reduce the risk thromboembolic events, even though this increases hemorrhagic complications. The updated Pipeline Flex embolization device Shield Technology has been created using a phosphorylcholine coating that reduces thrombogenicity and possibly need for therapy. However, because potential patients utilizing pipeline without therapy, not tested in human subjects its contribution preventing events...
We performed prospective randomized comparison of clinical and surgical outcomes flow diversion versus PVO bypass in patients with complex anterior circulation aneurysms.Open, prospective, randomized, parallel group, multicenter study intracranial aneurysms treatment was conducted. Patients neck is more than 4 mm wide, dome/neck ratio equal or less 2:1, which suitable for occlusion were included the study. A total 111 potential participants enrolled since March 2015. Additional propensity...
Endovascular embolization is an important modality in the treatment of brain AVMs. Nowadays staged method choice for prevention perioperative hemorrhagic complications. Current theory suggests that simultaneous occlusion more than 60% AVM volume induces significant redistribution local blood flow. That, turn, may lead to hemorrhage due rupture. Aside from angiographic findings, there still no predicts degree safe partial embolization. Intraluminal measurement flow velocity and pressure...
The paper presented a Personalized Intelligent Vascular 3D Simulator as an essential part of the Robotic Ecosystem LevshAI for remote endovascular neurosurgery. training is equipped with intelligent haptic feedback and Simulator. simulator creates unique personal vascular architecture according to individual patient parameters obtained from medical images. allows surgeons practice on choose best tactics before operation - personalized surgery. system provide environment identical what...
The multimodal approach to treatment of arteriovenous malformations yields good results. However, small and deep still pose a big problem for surgeons. Transvenous embolization was designed as an alternative the cases when endovascular is required conventional transarterial not available.A 41-year-old patient with binodal malformation in subcortical nuclei left hemisphere brain, which had previously become source massive parenchymal ventricular hemorrhage, operated on using and, first time...
Abstract Introduction: The algorithm of multimodal treatment (MMT) arteriovenous malformations (AVMs) combined with intent-to-cure and presurgery embolization benefits was developed. aim to analyze the effectiveness MMT compared unimodal in patient groups matched concerning clinical angiographic characteristics. Methods: A prospective cohort study safety performed. To estimate differences total occlusion rate complication embolization, a 1:1 group identified from Russian Endovascular Neuro...
Dural AVFs located in the posterior fossa are a rare entity. The objectives of study were to analyze anatomy dural AVFs, their endovascular treatment strategies, and clinical outcomes.Two centers retrospectively selected patients treated between January 2009 June 2018 having AVFs. We collected patient demographics, presentation, arterial venous outflow outcomes.Twenty-six endovascularly for type III, IV, or V, included. One hundred percent occluded. A transarterial approach was performed 23...
Pediatric arteriovenous malformations (AVMs) and pial/dural fistulas (AVFs) are rare but life-threatening complications that can lead to congestive heart failure hemorrhagic stroke in newborns pediatric patients. The pronounced shunting these conditions is associated with early necessitates aggressive surgical management. Here, the authors describe endovascular treatment of an atypical cerebral pial AVF a newborn.This formed direct communication between major artery (basilar artery) large...
The article discusses the etiology, pathogenesis, classification, principles of diagnosis and tactics surgical treatment dural arteriovenous fistulas. Two clinical cases successful patients with symptomatic fistulas are presented.
Background. Large and giant aneurysms (> 10 mm >25 mm, respectively), wide-necked (dome / neck ratio > 1.5) fusiform examples are challenging for both endovascular microsurgical intervention. Currently, there is a lack of universal approach in treating complex anterior circulatory aneurysms. Due to high morbidity mortality rates the absence common strategy, predictor analysis may have diagnostic relevance.Aim. We sought identify predictors unfavourable neurological outcomes...
Pial arteriovenous fistula (PAVF) is an extremely rare type of intracranial vascular congenital anomalies. The presented clinical case a unique example intrauterine diagnosis PAVF using fetal MRI at 30 weeks gestation, which allowed successful surgical treatment in the early neonatal period. demonstrates capabilities and estimation accompanying brain changes, are fully consistent with results postnatal cerebral angiography. Based on neuroimaging data, endovascular embolization detachable...
<h3>Introduction</h3> Application of liquid embolic agents (LEAs) is a method choice for endovascular treatment cerebral arteriovenous malformations (AVMs). <h3>Materials and methods</h3> Since January 2011, our team has treated 787 patients with AVMs in two large medical centers Novosibirsk Moscow. 41(5,2%) these were using only the PHIL agent (Spetzler-Martin I-III), 29 (70,7%) them was finalized 12 (29,3%) are undergoing further treatment. In presented paper, results considered....
The necessity of quick surgical treatment acute ruptured cerebral aneurysms was demonstrated in large studies by the ISAT and ISUIA, which also proved advantage endovascular method over one. Ballonassistence is widely used with wide neck unfavorable vascular anatomy, but radicality insufficient. aim this study to demonstrate efficacy safety stent-assisted embolization «acute» aneurysms. Material methods. A retrospective analysis 234 patients carried out. Results. Only coils were 40.6 % cases...
<h3>Background</h3> Pediatric arteriovenous malformations (AVM) and pial/dural fistulas (AVF) are rare but life-threatening diseases that can lead to congestive heart failure hemorrhagic stroke in newborns pediatric patients. The pronounced shunting these conditions is associated with early complications necessitates aggressive surgical management. <h3>Materials Methods</h3> For 10 years, our team at the Meshalkin National Medical Research Center Federal of Brain Neurotechnologies has...
<h3>Background</h3> Endovascular approach is one of the ways to successfully treat cerebral aneurysms. Currently, there are various techniques and devices increase radicality endovascular treatment. Despite variety available techniques, in recent years, flow diverts (FDs) have been increasingly preferred as a method for treating <h3>Materials Methods</h3> From January 2011 March 2023 at E.Meshalkin National Medical Research Center, Novosibirsk, Federal Center Brain Neurotechnologies, Moscow,...
<h3></h3> The purpose of our research was to compere the course structural epilepsy, which is both only manifestation malformation and debut disease in combination with intracerebral hemorrhage patients (pts) arteriovenous malformations (AVM) after endovascular combined treatment using Engel scale. study retrospective, non-randomized. <h3>Material Methods</h3> included confirmed cerebral AVM by angiography data concomitant epileptic seizures (both at onset disease). took into account...
<h3>Introduction</h3> Endosaccular coiling (EC) remains a gold standard treatment for small saccular aneurysms of anterior circulation (AC), however, flow diversion (FD) offers reasonable alternative. Currently, the benefits FD in such lesions are not well-established. <h3>Aim Study</h3> To compare safety and efficacy versus EC AC aneurysms, amenable to both methods. <h3>Methods</h3> In 2016–2019, 344 consecutive cases (FD n=154, n=190) were enrolled. All saccular, sized ≤14 mm, located at...
Introduction. Convexital localization of cerebral arteriovenous malformations (AVM) is a good prognostic criterion for successful endovascular treatment. Difficulties begin in the final stages large AVMs, transit nature afferents. Transvenous embolization has been developed as an alternative to microsurgery and radiosurgery limited range malformations. Materials, methods, results. January 2011 - December 2016, National Medical Research Center treated 440 patients with who underwent more than...