Uma Ranjan Lal

ORCID: 0000-0003-2506-5364
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemicals and Antioxidant Activities
  • Ethnobotanical and Medicinal Plants Studies
  • Phytochemicals and Medicinal Plants
  • Phytochemistry and Biological Activities
  • Piperaceae Chemical and Biological Studies
  • Natural product bioactivities and synthesis
  • Nigella sativa pharmacological applications
  • Curcumin's Biomedical Applications
  • Oral Health Pathology and Treatment
  • Medicinal Plants and Neuroprotection
  • Food Science and Nutritional Studies
  • Pharmacological Effects of Natural Compounds
  • Synthesis and biological activity
  • Computational Drug Discovery Methods
  • Phytochemical compounds biological activities
  • Phytochemical and Pharmacological Studies
  • Moringa oleifera research and applications
  • Advancements in Transdermal Drug Delivery
  • Berberine and alkaloids research
  • Psoriasis: Treatment and Pathogenesis
  • Phytochemistry and biological activities of Ficus species
  • Microbial Natural Products and Biosynthesis
  • Chromatography in Natural Products
  • Ginger and Zingiberaceae research

National Institute of Pharmaceutical Education and Research
2009-2025

Ayurvet (India)
2022-2024

National Institute of Pharmaceutical Education and Research
2019-2023

Birla Institute of Technology, Mesra
2013-2023

Shoolini University
2018-2023

Bombax ceiba is used traditionally to treat bone disorders, rheumatism, and joint pain. The aim of the study carry out osteogenic activity in-vitro anti-osteoporotic in-vivo stem bark B. in surgical ovariectomy model female rats.Plant drug: was extracted with solvents petroleum ether methanol using Soxhlet extraction. In-vitro osteoblastic proliferation performed UMR-106 cell lines. Both extracts were undergone acute toxicity as per OECD423 guidelines. Female Wistar albino rats 180-240 g (n...

10.1186/s12906-018-2299-1 article EN cc-by BMC Complementary and Alternative Medicine 2018-08-07

In this recent investigation, the focus centred on exploring potential phytoconstituents within bark of Dysoxylum malabaricum. A profiling strategy employing LC-HRMS (Liquid Chromatography-High Resolution Mass Spectrometry) was implemented for rapid identification compounds from extract. The crude extract underwent fractionation, resulting in isolation four previously known (1–4) and a novel cycloartane triterpenoid named Mahamanalactone (5). Compound 5 represents with modified ring-A,...

10.1080/14786419.2023.2298721 article EN Natural Product Research 2024-01-01

ABSTRACT Monoterpene glycosides are one of the secondary metabolites in plants and have various roles like flavour perception, enhancement, storage aroma, continuous release aroma so on. been classified into several groups, including acyclic, monocyclic, bicyclic irregular. This review article represents monoterpene identified isolated from different during research period last 17 years (2007–2023). These natural bioactive could be a good perspective for future pharma, perfumery, cosmetic industries.

10.1002/ffj.3862 article EN Flavour and Fragrance Journal 2025-03-26

Infections caused by HSV-2 are a public health concern worldwide, and there is still great demand for the discovery of novel anti-herpes virus agents effective against strains resistant to current antiviral agents. In this context, medicinal plants represent an alternative source active compounds developing efficient therapies. The aim study was evaluate activity Arisaema tortuosum, plant used in traditional medicine India. A chloroform soluble fraction leaves exhibited anti-HSV-2 with...

10.1055/a-1087-8303 article EN Planta Medica 2020-01-22

Background: Chebulinic acid (CA), a component in Terminalia chebula, exhibits antiulcer activity, but has poor aqueous solubility. Raft-forming systems incorporating solid dispersions (SDs) of CA, were developed to overcome its biopharmaceutical properties and prolong the gastric residence time for maximum activity. Methods: SDs formulated by solvent evaporation method using Eudragit EPO. Raft formulations consisted sodium alginate as polymer. Results: Release CA dissolution medium was 40%,...

10.4155/tde-2021-0062 article EN cc-by Therapeutic Delivery 2022-01-25

Arjunarishta (Parthadyarishta) is an important Ayurvedic formulation used for cardiovascular disorders and prepared by fermenting the decoction of specified plant materials using flowers Woodfordia fruticosa. In present communication, HPLC-PDA method was developed standardization quantitative estimation major antioxidant compounds, ellagic acid, gallic ethyl gallate, quercetin kaempferol as markers. The validated with respect to linearity, precision, accuracy, robustness. HPLC analysis...

10.3797/scipharm.0906-03 article EN cc-by Scientia Pharmaceutica 2009-01-01

The phytochemical investigation of chloroform extract from Piper betle var. haldia, Piperaceae, leaves has resulted in the isolation two new chemical constituents which were identified as 1-n-dodecanyloxy resorcinol (H1) and desmethylenesqualenyl deoxy-cepharadione-A (H4), on basis spectroscopic data 1D NMR (1H 13C) 2D (1H-1H COSY HMBC) well ESI-MS, FT-IR HR-ESI-MS analyses. Compounds H1 H4 showed excellent antioxidant DPPH free radical scavenging activity with IC50 values 7.14 μg/mL 8.08...

10.1080/14786419.2017.1380018 article EN Natural Product Research 2017-10-05

Bergenia ligulata Wall. Engl. is perennial herb used for the treatment urinary discharges, diseases of bladder, dysentery, menorrhagia, splenic enlargement and heart diseases. The aim present study was to investigate antimicrobial synergistic potential solvent fractions major phytocompound B. against bacterial fungal pathogens. (Petroleum ether, chloroform, ethyl acetate, remaining aqueous) methanolic extract rhizome bergenin were investigated by agar well diffusion broth microdilution...

10.1016/j.prmcm.2022.100076 article EN cc-by-nc-nd Pharmacological Research - Modern Chinese Medicine 2022-03-05

F. religiosa bark has been extensively used in traditional medicinal systems, such as Ayurveda, for its health benefits. The aim of this study was to investigate the secondary metabolites (phenolics and flavonoids) hydroalcoholic stem-bark extract from because plant proven have a beneficial effect on disorders. Therefore, pilot conducted identification quantification polyphenolic compounds using sophisticated chromatographical techniques UPLC-HRMS RP-HPLC-PDA. Additionally, total flavonoids,...

10.3390/separations10060338 article EN cc-by Separations 2023-05-31

In this study, phytochemical analyses of the chloroform extract Piper betle L. var. haldia and maghai, Piperaceae, leaves led to isolation two new phenolic derivatives: 1-n-decanoyl hydroxy-benzoic acid/1-n-decanoyl phenol (H2) 3-butylphenol (M1) on basis spectroscopic data 1D NMR (1H, 13C) 2D (1H - 1H COSY, HMBC) as well ESI-MS, FT-IR HR-ESI-MS analyses. Compounds H2 M1 showed excellent antioxidant DPPH free radical scavenging activity with IC50 values 10.66 μ/mL 13.65 μg/mL compared...

10.1080/14786419.2020.1762186 article EN Natural Product Research 2020-05-07

: Thymus serpyllum L. is aromatic plant of Lamiaceae family. Traditionally T. used to cure fever, cold, cough, and mensuration disorders. Present research focused on study in silico invitro antioxidant potential essential oil (TEO). Essential extracted from areal part by using, hydro-distillation method. In activity major phytoconstituents were studied using autoDock/vina tool. MD simulation was done Gromacs. Quantification thymol GCMS. vitro its active Thymol DPPH, FRAP ABTS Molecular...

10.1016/j.prmcm.2023.100280 article EN cc-by-nc-nd Pharmacological Research - Modern Chinese Medicine 2023-07-03
Coming Soon ...