Intracranial lesions can present a diagnostic challenge in patients without previously known immunosuppression. When focal neurological signs and seizures occur patient with no established medical history, an expansive brain lesion may be initially interpreted as neoplasm, influencing early clinical decisions regarding the extent of supportive measures. However, opportunistic infections, such cerebral toxoplasmosis, should remain on differential diagnosis - particularly after consideration...

Abstract Our objective was to establish and test a machine learning‐based screening process that would be applicable systematic reviews in pharmaceutical sciences. We used the SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, Research type) model, broad search strategy, learning tool (Research Screener) identify relevant references related y‐site compatibility 95 intravenous drugs neonatal intensive care settings. Two independent reviewers conducted pilot studies, including manual...

Today, major planning agendas in Europe steer the future of territorial organization towards an urban polycentric perspective. The accessibility to services general interest (SGI), a significant source spatial inequality Europe, is one key challenges address. However, instruments needed support implementation and monitoring policy measures regarding distribution of, SGI are still under-developed. Studies generally relate (intra)regional not national scale. When they do so, lose local...

Extreme Learning Machines (ELMs) are a versatile Machine (ML) algorithm that features as the main advantage possibility of seamless implementation with physical systems. Yet, despite success implementations ELMs, there is still lack fundamental understanding in regard to their optical implementations. In this context, work makes use an complex media and wavefront shaping techniques implement ELM playground gain deeper insight into these machines. particular, we present experimental evidences...

Abstract CO2-WAG (Water-Alternating-Gas) has been applied in offshore Brazilian oilfields to improve recovery rates and mitigate the environmental impact that venting produced CO2 would bring. Although is highly miscible oil under these reservoirs conditions, this gas also extremely mobile, its speciation aqueous phase drives reactions with carbonates can cause severe inorganic scaling problems production systems. It crucial, therefore, effectively design operations for mobility control and,...

Benign metastasizing leiomyoma (BML) is a rarely found entity with few documented cases in the literature, usually occurring women of reproductive age history myomectomy or hysterectomy. The leiomyomas can metastasize to several organs, lungs being most commonly affected. We report case 40-year-old female patient who presented at our institution low back pain. She underwent lumbar MR that revealed presence an expansive and compressive mass body L4. This was biopsied, corresponding no...

Educational gardens can be a significant resource in the promotion of environmental education, engaging both school population and general public. The main goal present study was to implement assess hands-on interventional program promote knowledge awareness plant-related topics at basic level. We report on educational project implemented with 8th-grade Portuguese students (mostly 13–14 years age), associated establishment, grounds, three representing distinct ecosystems. This collaborative...

Abstract The propagation of light in nonlinear optical media has been widely used as a tabletop platform for emulating quantum-like phenomena due to their similar theoretical description quantum fluids. These fluids are often study two-dimensional involving superfluid-like flows, yet turbulent regimes still remain underexplored. In this work, we the possibility creating and probing signatures kinetic energy spectrum. To that end, emulate disturb fluid with an all-optical defect using two...

Abstract When CO2 is injected into an aquifer, the generally colder than reservoir rock; this results in thermal gradients along flow path. The temperature variation has impact on solubility and kinetics of any mineral reactions. Core flood experiments associated reactive transport simulations were conducted to analyse effects during injection a dolomitic limestone aquifer quantify how reactivity are affected. by injecting acidified brine Edwards Limestone core sample. A back pressure 400...

Summary Vapor/liquid-equilibria (VLE) calculations, particularly involving the phase behavior of carbon dioxide (CO2) and hydrogen sulfide (H2S), are used in scale-prediction modeling. In this work, impact VLE calculations for CO2- H2S-rich gas phases acid- sour-gas mixtures on is evaluated. Three equations state (EOSs)—Soave-Redlich-Kwong (SRK) (Soave 1972), Peng-Robinson (PR) (Peng Robinson 1976), Valderrama-Patel-Teja (VPT) (Valderrama 1990)—are implemented Heriot-Watt model calculations....

Sildenafil is used to treat pulmonary hypertension in neonatal intensive care unit (NICU) settings. As multiple intravenous (IV) medications are co-administered NICU settings, we sought investigate the physicochemical compatibility of sildenafil with a range IV drugs. 600 mcg/mL or 60 was mixed 1:1 secondary drug solution simulate Y-site co-administration procedures. Physical evaluated by visual observation against black and white background under polarized light for two hours changes...

Abstract Purpose To investigate the physicochemical compatibility of caffeine citrate and base injections with 43 secondary intravenous (IV) drugs used in Neonatal Intensive Care Unit (NICU) settings. Methods Caffeine (20 mg/mL or 10 mg/mL) injection (10 were mixed a volume ratio 1:1 drug solution to simulate Y-site co-administration procedures NICUs. Physical was evaluated based on visual observation for 2 h, against black white background under polarised light, changes colour,...

Immune thrombocytopenia (ITP) is characterized by isolated manifesting with mucocutaneous bleeding symptoms, generally mild to moderate. The presence of severe symptoms or complications rare but can be life-threatening and should promptly diagnosed treated. We present the case a 14-year-old female presenting abdominal tenderness signs peritoneal irritation found exhibit petechial rash in buccal mucosa, scant petechiae, superficial ecchymosis both arms legs on physical examination. Laboratory...

Abstract Vapour-Liquid Equilibria (VLE) calculations, particularly involving the phase behaviour of CO2 and H2S, are used in scale prediction modelling. In this work, impact VLE calculations for H2S-rich gas phases acid sour mixtures on is evaluated. Three Equations State (EOS), viz. Soave-Redlich-Kwong (SRK), Peng-Robinson (PR) Valderrama-Patel-Teja (VPT), implemented Heriot-Watt model calculations. The solubility single-component H2S water a mixture were compared with experimental data...

Abstract Injection of Low Sulphate Seawater (LSSW) instead untreated Full (FSSW) is widely used to mitigate barium sulphate (BaSO4) scaling risk at production wells. LSSW injection may no longer be required when the (Ba2+) concentrations in produced water drop below a certain threshold. Such trigger value could estimated from BaSO4 precipitation tendency. Relaxation requirements for Reduction Plant (SRP) can significantly reduce operational costs. This study investigates impact several...