A5026604549- Acute Ischemic Stroke Management
- Peripheral Neuropathies and Disorders
- Neurological and metabolic disorders
- Cerebrovascular and Carotid Artery Diseases
- Long-Term Effects of COVID-19
- Infectious Encephalopathies and Encephalitis
- Autoimmune Neurological Disorders and Treatments
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Parkinson's Disease Mechanisms and Treatments
- RNA regulation and disease
- Multiple Sclerosis Research Studies
- Glycogen Storage Diseases and Myoclonus
- Orthopedic Surgery and Rehabilitation
- Neurological disorders and treatments
- Peripheral Nerve Disorders
- Prion Diseases and Protein Misfolding
- Polyomavirus and related diseases
- Nuclear Receptors and Signaling
- Epilepsy research and treatment
- Stroke Rehabilitation and Recovery
- Chemotherapy-related skin toxicity
- Viral Infections and Immunology Research
Sunway University
2024
National University of Malaysia
2021-2023
University Kebangsaan Malaysia Medical Centre
2017-2022
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021
Hospital Kuala Lumpur
2018
Anti-IgLON5 disease is a recently described neurologic that shares features of autoimmunity and neurodegeneration. Abnormal movements appear to be frequent important but have not been characterized are underreported. We describe the frequency types movement disorders in series consecutive patients with this disease.In retrospective, observational study, presence phenomenology were assessed standardized clinical questionnaire. Available videos centrally reviewed by 3 experts...
Neurological involvement associated with SARS-CoV-2 infection has been reported from different regions of the world. However, data South East Asia are scarce. We described neurological manifestations and their factors among hospitalized COVID-19 patients an academic tertiary hospital in Malaysia.
In conjunction with the third regional Southeast Asian (SEA) therapeutic plasma exchange (TPE) conference in Kuala Lumpur, Malaysia, 25 clinicians and researchers from SEA South countries attended inaugural strategy meeting for establishment of a TPE consortium neurological disorders. The primary objective was to establish collaboration improve delivery services SEA. A pre-meeting survey conducted gather insights on disease spectrum, contextual practice challenges, need consensus. Challenges...
A 54-year-old man with type 2 diabetes mellitus for 10 years on metformin 1 g two times per day and gliclazide 40 mg daily, bronchial asthma 30 metered-dose inhalers budesonide puffs salbutamol as required. There was no history of neuropsychiatry
Bickerstaff brainstem encephalitis (BBE) is a rare autoimmune characterised by ataxia, ophthalmoplegia and altered consciousness. An overlap between BBE with Guillain-Barré syndrome (GBS) shows similar clinical immunological features. We report case of GBS secondary to
Anxiety has been increasingly recognized as part of the psychosocial health issues in COVID-19 patients. However, impact this topic may be underestimated low- and middle-income countries. This study aimed to estimate prevalence risk factors anxiety patients compared controls a local tertiary teaching hospital Malaysia.
Transverse myelitis in multiple sclerosis is typically a short cord lesion with patchy distribution. Rarely, longitudinally extensive transverse can be seen those highly active disease or frequent relapses. The recognition of this uncommon phenotype important as the treatment largely different from other demyelinating diseases. We describe patient relapsing-remitting on interferon beta-1a who developed LETM after
Levodopa is the most effective medical treatment for Parkinson's disease (PD) to date. As dopamine known increase cardiac inotropism and vasomotor tone, peripheral decarboxylase inhibitor coadministered suppress conversion of levodopa dopamine. poses potential cardiovascular risks, thus its use in patients with existing coronary artery needs be carefully monitored. We report a case an elderly male newly diagnosed PD who developed non-ST-elevation myocardial infarction following (Madopar) initiation.
A 40-year-old man presented with painless swelling of the neck for 3 years. He was well until months prior to presentation when he started losing weight and feeling lethargic. Clinical examination showed an enlarged left cervical lymph node measuring about 4×4 cm. Lymph biopsy
Lithium is a medication with variety of medical usage for various diseases including bipolar mood disorder. As the therapeutic window lithium narrow, its commonly associated toxicity. toxicity affects multiple systems especially central nervous system, leading to neuropsychiatric complications. Haemodialysis an effective method removal in severe such as neurotoxicity electroencephalogram changes. We describe case electroencephalographic abnormalities which was reversed following haemodialysis.
Basilar artery occlusion (BAO) is not common, but a potentially fatal neurological emergency. The clinical spectrum ranges from mild dizziness to tetraparesis or locked-in syndrome. Computed tomography (CT) of the brain, although insensitive, can be highly valuable in detecting early sign BAO. We report case acute BAO secondary cardioembolism with hyperdense basilar on noncontrasted CT brain. patient was beyond window period for intravenous thrombolysis and devoid availability endovascular...
An 87-year-old man presented with involuntary movements of his fingers for 3 months. Clinical examination showed dystonia choreoathetosis hands and (Video 1). Pinprick sensation was reduced to ankles vibration sense absent up shoulders costal margin bilaterally. Investigations revealed hemoglobin 10.1 g/dL, mean corpuscular volume 94.6 fL, vitamin B12 level <92 pmol/L, the presence antiparietal cell antibody. He diagnosed pernicious anemia treated intramuscular cyanocobalamin (1,000 μg...
Lymphoma is known to cause a wide spectrum of neurological disorders, including local lymphomatous infiltration and paraneoplastic syndrome. More commonly, the complications in patients with lymphoma are due use chemotherapeutic agents. Chemotherapy-induced syndromes encompass encephalopathy, seizures, arachnoiditis, cranial neuropathies, caudal equina syndrome, peripheral neuropathy.[1] We herein describe young girl who developed acute myelitis following intrathecal chemotherapy.
Background & Objective: Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus (DM). Vitamin D deficiency has been shown to be prevalent among patients with DM, particularly in those DPN. This study aimed look at the association serum vitamin level DM. Methods: was comparative cross- sectional conducted tertiary hospital Malaysia. Fifty diabetic DPN and fifty without were recruited. Serum determined by measuring 25-hydroxyvitamin [25(OH)D] level. The...
Varicella is an acute exanthematous, highly contagious disease caused by varicella-zoster virus (VZV). Neurological complications are the second most common complication in 0.1%–0.75% of cases following secondary bacterial infection skin lesion.[1] The neurological include cerebellar ataxia, meningitis, encephalitis, stroke or stroke-like episodes, myelitis, and vasculopathy.[2] There numerous evidence reports on VZV cerebellitis mainly childhood including preeruptive cerebellitis. However,...
Abstract A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness her National Institutes of Health Stroke Scale (NIHSS) score 17. An emergency CT perfusion showed right M1 segment occlusion more than 50% penumbra. given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. immediate diagnostic angiogram intention to treat, owing presence large...