A5044403862- Head and Neck Cancer Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer-related molecular mechanisms research
- Body Composition Measurement Techniques
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Nutritional Studies and Diet
- Air Quality and Health Impacts
- Dietary Effects on Health
- Nutrition and Health in Aging
- Viral-associated cancers and disorders
- Cardiovascular Health and Risk Factors
- Inflammatory Bowel Disease
- Pain Mechanisms and Treatments
- Oral Health Pathology and Treatment
- Smoking Behavior and Cessation
- Adipokines, Inflammation, and Metabolic Diseases
- Foreign Body Medical Cases
- Cancer Treatment and Pharmacology
- Mast cells and histamine
- Heavy Metal Exposure and Toxicity
- Cleft Lip and Palate Research
- Gastrointestinal motility and disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Frailty in Older Adults
Ganzhou People's Hospital
2016-2025
ShenZhen People’s Hospital
2024-2025
Zhujiang Hospital
2022-2025
Southern Medical University
2022-2025
Shenzhen University
2017-2025
Huazhong University of Science and Technology
2023-2024
Union Hospital
2023-2024
Shenzhen Sixth People's Hospital
2016-2017
Nanchang University
2016
Guangdong Medical College
2013-2016
The pattern-recognition receptor NOD2 senses bacterial muropeptides to regulate host immunity and maintain homeostasis. Loss-of-function mutations in are associated with Crohn's disease (CD), but how the variations microbial factors influence signaling pathology is elusive. We demonstrate that Firmicutes peptidoglycan remodeling enzyme, DL-endopeptidase, increased ligand level gut impacted colitis outcomes. Metagenomic analyses of global cohorts (n = 857) revealed DL-endopeptidase gene...
In clinical practice, an unexplained discordance between percentage haemoglobin A1c (HbA1c) and the progression of diabetes its complication is observed. HbA1c determined by blood glucose level red cell (RBC) lifespan. Whether RBC lifespan changes in diabetic patients remains undefined because lack a convenient accurate measurement method. present study, we aim to observe type 2 with poor control endogenous carbon monoxide (CO) using rapid simplified CO breath test machine. The lifespan,...
Background Prediabetes, impacting a third of the adult Chinese population, is linked to variety detrimental health outcomes. However, scant research has delved into factors that affect regression from prediabetes normal glucose regulation (NGR) in middle-aged and elderly adults. Methods We conducted longitudinal analysis 2,655 adults, aged 45 years above, drawing data wave 1 3 China Health Retirement Longitudinal Study (CHARLS). employed stepwise logistic model identify associated with NGR....
Dihydroartemisinin (DHA) exhibits anticancer activity in a number of human cancer cells. However, it is still unknown whether DHA has effect on nasopharyngeal (NPC) cells.To investigate the CNE-2 cells.Cell cycleand invasion assay were used to detect Protein molecular differences examined by Western blot.DHA strongly inhibited cell proliferation induced cycle G1 arrest and apoptosis In addition, motility, invasion, colony formation suppressed DHA.DHA shows significant effects NPC cells, may...
Background Accumulating evidence have demonstrated that tobacco smoke exposure (TSE) causes damage to human mental issues. However, previous studies almost focus on the individual smoking patterns and some inconsistent results are reported. Serum cotinine is a reliable quantitative biomarker of TSE. This study aims explore association serum with depression sleep disorders potential gender differences. Methods Data from National Health Nutrition Examination Survey (NHANES) 2007-2014 was used....
Abstract The association of Healthy Eating Index 2020 (HEI‐2020), especially its components with systemic inflammatory biomarkers, has not been examined. aim this study was to investigate the relationship between HEI‐2020 and provide a dietary pattern suggestion combat inflammation. Participants aged 20 years older complete information on two reliable recalls, blood cell counts demographic characteristics, were recruited from six NHANES cycles 2007 2018. Weighted general linear methods...
Our colleagues have reported previously that human pancreatic progenitor cells can readily differentiate into insulin-containing cells. Particularly, transplantation of these cell clusters upon in vitro induction for 3-4 w partially restores hyperglycemia diabetic nude mice. In this study, we used fetal to identify the forkhead protein FoxO1 as key regulator differentiation. Thus, 1 week led increase <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Glycosylated hemoglobin (HbA1c) is an important criterion for the diagnosis of diabetes and indicator blood glucose level. The red cell (RBC) lifespan heterogeneity sufficient to influence HbA1c interpretation. In this study, we recruited 120 patients with mellitus 85 nondiabetic controls. RBC were detected by high-performance liquid chromatography advanced carbon monoxide breath detection method, respectively. Potential correlations gender age analyzed a receiver operator characteristic...
Background Minerals and trace elements were involved in the pathogenesis progression of diabetes. However, association mixed exposure to essential toxic with gestational diabetes mellitus (GDM) is poorly understood. Objective This study aims examine associations between serum calcium (Ca), iron (Fe), zinc (Zn), copper (Cu), magnesium (Mg), cadmium (Cd) concentrations early pregnancy GDM risk Chinese pregnant women. Method A total 1,168 women included this prospective cohort study. The...
Sarcopenia has been identified as a risk factor for increased mortality in individuals with CKD. However, when considering mild kidney dysfunction prior to CKD, the impact of sarcopenia on adverse outcomes, particularly mortality, remains uncertain.
Sarcopenia has been a serious concern in the context of an increasingly aging global population. Existing detection methods for sarcopenia are severely constrained by cumbersome devices, necessity specialized personnel, and controlled experimental environments. In this study, we developed innovative wearable fabric system based on conductive flexible sensor array. This demonstrates remarkable pressure-sensing capabilities, with high sensitivity 18.8 kPa−1 extraordinary stability. It also...
Abstract Background Prolonged chronic inflammation is a risk of various health disorders. Dietary patterns have been associated with inflammation. Healthy eating index 2020 (HEI-2020) has status. However, the association HEI-2020 and its components systemic inflammatory biomarkers not examined. Methods Participants aged 20 years older completed information on two reliable dietary recalls, blood cell counts demographic characteristics were recruited from 6 NHANES circles 2007 to 2018....
Objective To investigate the features of resting energy expenditure (REE) in patients with well controlled type 2 diabetes mellitus (T2DM). Methods Totally 45 T2DM stable blood glucose were enrolled. The general conditions, biochemical indicators, measurements REE ( MREE), and basal (BEE) calculated Harris-Benedict formula (HBEE) Owen (OBEE) recorded compared. Results MREE had no significant difference HBEE or OBEE (P ＞ 0. 05). Correlation analysis showed that was significantly correlated...