A5037446400- Cancer Genomics and Diagnostics
- Management and Organizational Studies
- Genomics and Rare Diseases
- Healthcare Systems and Reforms
- Cancer-related molecular mechanisms research
- Insect Resistance and Genetics
- Global Maternal and Child Health
- Conservation, Biodiversity, and Resource Management
- Soil Carbon and Nitrogen Dynamics
- Urban Transport and Accessibility
- COVID-19 and Mental Health
- Economic and Environmental Valuation
- RNA modifications and cancer
- Mental Health Research Topics
- Ethics and Social Impacts of AI
- Reproductive Biology and Fertility
- Global Health Care Issues
- Plant Genetic and Mutation Studies
- Cybersecurity and Cyber Warfare Studies
- Genetic factors in colorectal cancer
- COVID-19 Pandemic Impacts
- Insect Utilization and Effects
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Posttraumatic Stress Disorder Research
Tianjin University
2022-2025
University of Liverpool
2023-2024
Chinese Academy of Sciences
2022-2024
Shenzhen Bioeasy Biotechnology (China)
2019-2024
Development Research Center
2021-2024
Institute of Psychology, Chinese Academy of Sciences
2021-2024
University of Chinese Academy of Sciences
2021-2024
Shenyang Jianzhu University
2024
Xijing Hospital
2024
Air Force Medical University
2024
Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used each operation, such as quality control, adapter trimming filtering. These tools often insufficiently fast most developed using high-level programming languages (e.g. Python Java) provide limited multi-threading support. Reading loading multiple times also renders slow I/O inefficient.We fastp an ultra-fast preprocessor with useful...
Taking a procedural justice perspective, we examined the effect of guanxi practices in human resources management (i.e., making decisions on basis personal relationships) employees' trust Chinese organizations. Two studies were conducted. In first, survey study, found negative management, which was mediated by perceived justice. second, an experimental that varied as function bases: favoring nephew or hometown fellow lowered trust, but college schoolmate close friend did not. Theoretical and...
Abstract Motivation Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used each operation, such as quality control, adapter trimming, filtering. These tools often insufficiently fast most developed using high-level programming languages (e.g., Python Java) provide limited multi-threading support. Reading loading multiple times also renders slow I/O inefficient. Results We fastp an ultra-fast...
Under Xi Jinping's leadership, China has actively promoted “Internet sovereignty” as a means to reshape the discourse and practices of global cyber governance. By analyzing Chinese‐language literature, this article unpacks Chinese Internet sovereignty. Despite significant interest in promoting it China's normative position on cyberspace, we find that formulations sovereignty are fragmented, diverse, underdeveloped. There substantial disagreements uncertainty over what is how can be put into...
Coronavirus disease 2019 (COVID-19) has affected more than 5 million people around the world and killed 300,000 people; thus, it become a global public health emergency. Our objective was to investigate mental of hospitalized patients diagnosed with COVID-19.The PTSD checklist for DSM-5 (PCL-5), Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), Trauma Exposure Scale, abbreviated version Connor-Davidson Resilience (CD-RISC-10), Perceived Social Support (PSSS)...
Abstract Background Artificial Intelligence (AI) innovations in radiology offer a potential solution to the increasing demand for imaging tests and ongoing workforce crisis. Crucial their adoption is involvement of different professional groups, namely radiologists radiographers, who work interdependently but whose perceptions responses towards AI may differ. We aim explore knowledge, awareness attitudes amongst groups radiology, analyse implications future these technologies into practice....
This study employs the undesirable output super-efficiency SBM-DEA model to reassess green innovation efficiency (GIE) of 30 Chinese provinces from 2011 2020. We pioneer examination public attention (PA) influence on GIE and spatial spillover effects, employing Durbin model. Additionally, a mediation model, incorporating big data technology as mediator, is adopted. Key findings are follows: 1) Significant correlations exist in PA GIE. 2) Improved one province can help enhance neighboring but...
Removing duplicates might be considered as a well-resolved problem in next-generation sequencing (NGS) data processing domain. However, NGS technology gains more recognition clinical application, researchers start to pay attention its errors, and prefer remove these errors while performing deduplication operations. Recently, new called unique molecular identifier (UMI) has been developed better identify reads derived from different DNA fragments. Most existing duplicate removing tools cannot...
Defective nucleotide modifications of mitochondrial tRNAs have been associated with several human diseases, but their pathophysiology remains poorly understood. In this report, we investigated the pathogenic molecular mechanism underlying a hypertension-associated 4435A→G mutation in tRNAMet. The m.4435A→G affected highly conserved adenosine at position 37, 3′ adjacent to tRNA's anticodon, which is important for fidelity codon recognition and stabilization. We hypothesized that introduced an...
How do professionals respond when they are required to conduct work that does not match with their identity? We investigated this situation in an English public services organization where a major redesign initiative engage new tasks did want do. Based on our findings, we develop process model of professional identity restructuring includes the following four stages: (1) resisting change and mourning loss previous work, (2) conserving avoiding (3) parking learning (4) retrieving modifying...
Germline variations may contribute to lung cancer susceptibility besides environmental factors. The influence of germline mutations on and their correlation with somatic has not been systematically investigated.In this study, from 1,026 non-small cell (NSCLC) patients were analyzed a 58-gene next-generation sequencing (NGS) panel containing known hereditary cancer-related genes, categorized based American College Medical Genetics Genomics (ACMG) guidelines in pathogenicity, the corresponding...
Abstract New technologies are equivocal, triggering sensemaking responses from the individuals who encounter them. As an ‘epistemic technology’ AI poses new challenges to expertise and jurisdictions of professionals. Such may be interpreted quite differently, however, depending on specialized role identities which develop within wider professional domain. We explore these intra‐professional groupings posed by through empirical study professionals playing different roles (front‐line, hybrid...
Microbial physiology plays a pivotal role in construction of superior microbial cell factories for efficient biosynthesis desired products. Here we identify that pcnB repression confers improved overproduction free fatty acids (FFAs) Escherichia coli through genome-scale CRISPRi modulation combining fluorescence-activated sorting (FACS) and next-generation sequencing (NGS). The can enhance the stability abundance transcripts genes involved proton-consuming system, thereby supporting global...
Objective As COVID-19 persists around the world, it is necessary to explore long-term mental health effects in survivors. In this study, we investigated outcomes of survivors at 6 and 12 months postdiagnosis. Methods Posttraumatic stress disorder (PTSD checklist for DSM-5, PCL-5), depression (PHQ-9), anxiety (Generalized Anxiety Disorder Scale, GAD-7), resilience (Connor-Davidson Resilience CD-RISC-10), perceived social support (PSSS), personality traits (Chinese Big Five Personality...
The inner shell-regulated exciton dynamics, fluorescence blinking and photon emission properties of environmentally friendly InP/ZnSe/ZnS quantum dots.
Abstract In this article, we explore how less dominant actors, service users in our case, utilize different types of power to influence more professional groups during processes co‐production. Drawing on semi‐structured interviews with 48 involved healthcare improvement research, illuminate the crucial role normative contrast extant co‐production literature, which largely focuses structural or resource power, show is created by leverage over actors. We highlight relationship between...
China’s healthcare reform programme continues to receive much attention. Central these discussions has been how the various financial incentives underpinning efforts are negatively impacting on workforce. Research document trends, however, qualitative analysis of impact motivation workers remains underdeveloped. Furthermore, application motivational theories make sense worker experiences yet be undertaken. The purpose our paper is present a comparative case study account across urban China....
Abstract Nitrogen (N) deposition poses a serious threat to terrestrial biodiversity and alters plant soil microbial community composition. Species turnover nestedness reflect the underlying mechanisms of variations in However, it remains unclear how species contribute different responses taxonomic groups (plants microbes) N enrichment. Here, based on 13‐year consecutive multi‐level addition experiment semiarid steppe, we partitioned β ‐diversity into components explored why communities...