A5008542352- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Peripheral Artery Disease Management
- Neurological Complications and Syndromes
- Migraine and Headache Studies
- Receptor Mechanisms and Signaling
- Veterinary Pharmacology and Anesthesia
- Intensive Care Unit Cognitive Disorders
- Neurological Disorders and Treatments
- Biomedical and Chemical Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Psychiatric care and mental health services
- Pharmacological Effects and Assays
- Neurosurgical Procedures and Complications
- Clinical practice guidelines implementation
University of Lucerne
2024-2025
Luzerner Kantonsspital
2019-2025
University of Zurich
2010
Background: There are limited therapeutic options in cases of failed reperfusion (modified thrombolysis cerebral infarction [mTICI] score < 2b) after stent-retriever and/or aspiration based endovascular treatment (EVT) for acute ischemic stroke. Despite the absence data supporting its use, rescue therapy (balloon angioplasty stent implantation) is often utilized such cases. Studies to large vessel occlusions, while outcomes and complications medium/distal occlusions (MDVOs) have not been...
Acute ischemic stroke outcomes depend on various factors. We investigated whether the outcome-relevant factor (ORF) profiles differ between different vascular territories and therapeutic strategies. In this retrospective study, we analyzed 410 comprehensive center patients [median age of 70 years (IQR 57-80), 125 women (30%)] by analyzing five groups: all patients, with infratentorial infarctions only (n = 80), supratentorial 330), without 269), mechanical thrombectomy 61). Outcomes were...
Objectives: Whether different antihypertensive drug classes in high blood pressure (HBP) pre-stroke treatment affect dynamic cerebral autoregulation (dCA), stroke severity, and outcome. Methods: Among 337 consecutive ischemic patients (female 102; median age 71 years [interquartile range, [IQR 60; 78]; NIHSS 3 1; 6]) with assessment of dCA, 183 exhibited the diagnosis HBP. dCA parameters’ gain phase were determined by transfer function analysis spontaneous oscillations flow velocity....
Cardiac high-sensitivity troponin T (hs-cTnT) is linked to the cardioembolic origin, severity, and outcome of acute ischemic stroke. Furthermore, larger brain infarctions are often accompanied by impaired dynamic cerebral autoregulation (dCA), which also indicative a poor prognosis.
Objectives: Blood pressure (BP) management is challenging in patients with acute ischemic supratentorial stroke undergoing recanalization therapy due to the lack of established guidelines. Assessing dynamic cerebral autoregulation (dCA) may address this need, as it a bedside technique that evaluates transfer function phase very low-frequency (VLF) range (0.02–0.07 Hz) between BP and blood flow velocity (CBFV) middle artery. This prognostically relevant parameter, lower values associated...
Ischemic stroke in patients with a systemic tumor disease or cancer not remission (active tumors) is less well understood. Some aspects of such paraneoplastic strokes remind on generalized cerebrovascular disorder. We hypothesized that regulation active different from other who have no disease.
Zusammenfassung Es werden die von wachen unbehandelten Hauskatzen erhaltenen Kreislaufparameter (EKG, Herzschlagfrequenz und Blutdruck) beschrieben. Diese sollen als Vergleichswerte bei experimentellen oder diagnostischen Untersuchungen dienen. Die telemetrisch registrierte beträgt 128 ± 17/min. der direkt gemessene Blutdruck systolisch 135 14 diastolisch 101 mm Hg. Summary Electrocardiogram, heart rate and blood pressure in the domestic cat (Felis catus) Using 28 healthy adult cats of both...