A5086454799- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Neuroscience and Neural Engineering
- Cell Image Analysis Techniques
- Microfluidic and Bio-sensing Technologies
- Nanofabrication and Lithography Techniques
- Biomedical and Engineering Education
- Microfluidic and Capillary Electrophoresis Applications
- Problem and Project Based Learning
- Experimental Learning in Engineering
University of Virginia
2021-2023
McCormick (United States)
2021
Austin Peay State University
2021
Fluid flow is an integral part of microfluidic and organ-on-chip technology, ideally providing biomimetic fluid, cell, nutrient exchange as well physiological or pathological shear stress. Currently, many the pumps that actively perfuse fluid at rates are incompatible with use inside cell culture incubators, require tubing connections, too large to run devices in a confined space. To address these issues, we developed user-friendly impeller pump uses 3D-printed device recirculate cells...
Bubbles are a common cause of microfluidic malfunction, as they can perturb the fluid flow within micro-sized features device. Since gas bubbles form easily warm cell culture reagents, degassing is often necessary for biomicrofluidic systems. However, fabrication microscale degasser that be used modularly with pre-existing chips may cumbersome or challenging, especially labs not equipped traditional microfabrication, and current commercial options expensive. Here, we address need an...
Resin 3D printing is attractive for the rapid fabrication of microscale cell culture devices, but common resin materials are unstable and cytotoxic under conditions. Strategies such as leaching or overcuring insufficient to protect sensitive primary cells white blood cells. Here, we evaluated effectiveness using a parylene C coating commercially available clear resins prevent leaching, degradation microfluidic absorption small molecules. We found that significantly improved both...
A Quantitative Analysis Lab class was developed that began with 9 weeks of student preparation for the Quant Escape Game (QEG) where students learned fundamentals quantitative analysis. The followed by four-week QEG, an active-learning, cooperative-learning, and problem-based learning experience in which used their knowledge analysis to solve given problems. Students reported game caused them learn, thinking advance all semester long instead simply going through motions. were motivated...
Resin 3D printing is attractive for fabrication of microscale cell-culture devices, but common resin materials are unstable and toxic under cell culture conditions or extended periods fluid flow. Here, we evaluated the effectiveness using parylene-C coating commercially available clear resins to prevent cytotoxic leaching, degradation microfluidic absorption small molecules. We found that significantly improved both cytocompatibility with primary white blood cultures material integrity...
Resin 3D printing is attractive for rapid fabrication of microscale cell culture devices, but common resin materials are unstable and cytotoxic under conditions. Strategies such as leaching or over-curing insufficient to protect sensitive primary cells white blood cells. Here, we evaluated the effectiveness using parylene-C coating commercially available clear resins prevent leaching, degradation microfluidic absorption small molecules. We found that significantly improved both...
Abstract Stereolithographic (SL) 3D printing, especially digital light processing (DLP) is a promising rapid fabrication method for bio-microfluidic applications such as clinical tests, lab-on-a-chip devices, and sensor integrated devices. The benefits of printing lead many to believe this will accelerate the use microfluidics, but there are number potential obstacles overcome bioanalytical labs fully utilize technology. For commercially available materials, includes challenges in producing...
Resin 3D printing is attractive for rapid fabrication of microscale cell culture devices, but common resin materials are unstable and cytotoxic under conditions. Strategies such as leaching or over-curing insufficient to protect sensitive primary cells white blood cells. Here, we evaluated the effectiveness using parylene-C coating commercially available clear resins prevent leaching, degradation microfluidic absorption small molecules. We found that significantly improved both...