A5088606038- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Anesthesia and Pain Management
- Noise Effects and Management
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Monoclonal and Polyclonal Antibodies Research
- Supramolecular Self-Assembly in Materials
- Alzheimer's disease research and treatments
- Vehicle Noise and Vibration Control
- Cardiac, Anesthesia and Surgical Outcomes
- Hydraulic and Pneumatic Systems
- Pregnancy and Medication Impact
- Neonatal Respiratory Health Research
- Aerodynamics and Acoustics in Jet Flows
- Aerospace and Aviation Technology
- Nausea and vomiting management
- Pediatric Urology and Nephrology Studies
- Pediatric Pain Management Techniques
- Pregnancy-related medical research
- Cardiovascular Issues in Pregnancy
- Pain Management and Opioid Use
- Aluminum toxicity and tolerance in plants and animals
- Acoustic Wave Phenomena Research
University of Michigan
2023-2025
BioSurfaces (United States)
2023-2025
Pharmaceutical Biotechnology (Czechia)
2023
The University of Texas at Austin
2018-2022
University Hospitals of Leicester NHS Trust
2021
UPMC Altoona
2020
Pennsylvania State University
2020
The Open University
2010-2014
The University of Texas Health Science Center at Houston
2003-2008
Universidad Politécnica de Madrid
2007
Magnesium sulfate is used widely to prevent eclamptic seizures in pregnant women with hypertension, but few studies have compared the efficacy of magnesium that other drugs. Anticonvulsant prophylaxis phenytoin for eclampsia has been recommended, there are virtually no data support its efficacy. Our objective was compare preventing hypertensive during labor.
Background Reports indicate that the administration of epidural analgesia for pain relief during labor interferes with and increases cesarean deliveries. However, only a few controlled trials have assessed effect on incidence delivery. The authors' primary purpose in this randomized study was to evaluate effects rate deliveries by providing suitable alternative: patient-controlled intravenous analgesia. Methods Seven hundred fifteen women mixed parity spontaneous at full term were randomly...
During a 12-year period, when more than 106,000 women were delivered, 28 with peripartum heart failure of obscure etiology that initially was diagnosed as cardiomyopathy studied. None had obvious underlying cardiac disease or iatrogenic fluid overload, and in all an assiduous search for cardiovascular launched. In 21 these women, attributed to chronic (chronic hypertension 14, forme fruste mitral stenosis four, morbid obesity one) viral myocarditis. Importantly, also multiple compounding...
Highlights•Short (s)TDP43 isoforms are created as a by-product of TDP43 autoregulation•sTDP43 is strictly regulated by NMD, the proteasome, and autophagy•sTDP43 potent inhibitor splicing activitySummaryThe nuclear RNA-binding protein integrally involved in pathogenesis amyotrophic lateral sclerosis (ALS) frontotemporal lobar degeneration (FTLD). Previous studies uncovered N-terminal that predominantly cytosolic localization, prone to aggregation, enriched susceptible spinal motor neurons. In...
Objective: To assess the prevalence of head circumference to abdomen (HC/AC) asymmetry among small for gestational age (SGA) fetuses, and determine likelihood adverse outcomes asymmetric symmetric SGA infants compared with their appropriate (AGA) counterparts. Methods: In a retrospective cohort study, we analyzed consecutive live-born singletons women who had antepartum sonography within 4 weeks delivery delivered between January 1, 1989 September 30, 1996. A age–specific HC/AC nomogram was...
Background Combined spinal-epidural (CSE) analgesia produces rapid-onset pain relief and allows ambulation in early labor. Epidural local anesthetics may contribute to an increase operative deliveries by decreasing perineal sensation causing motor weakness. Operative delivery rates might be reduced with CSE, avoiding or delaying administration of anesthetics. This study compares the associated a CSE technique those intravenous meperidine for labor analgesia. Methods Healthy parturients at...
Three blinded observers on three separate occasions calculated four commonly employed patellar height ratios the knees of 15 patients who had lateral radiographs each. The used same measurement instrument, a hand-held goniometer ruler, to determine relative reliability each ratio. measurements by were examined, and error methods tested statistically. Among measuring that we studied, Blackburne-Peel method most consistently reproduced index. Interobserver averaged 0.06 for all ratios. Values...
Objectives: Our aim was to evaluate the utility of color flow mapping in prediction placental myometrial invasion women with Cesarean delivery. Methods Ultrasound performed on implantations potential proximity hysterotomy scar. The smallest thickness measured under placenta degree attenuation this area and note made unusual vascular lakes. Results Two hundred fifteen placentas prior scar underwent Doppler mapping. Of 20 previa delivery, 15 had hysterectomy for bleeding complications nine...
There are a number of risk factors for traumatic injury in veterinary practice but there is little information on the prevalence injuries or associated with this profession.To identify sustained by veterinarians and groups most at different types injury.Cross-sectional survey Australian veterinarians. Subjects were asked whether they had ever significant work-related injury, less serious acute work last 12 months, chronic musculoskeletal problem dog cat bites. The gender, type decade...
Bispecific antibodies (bAbs) that engage cerebrovascular targets, induce transport across the blood-brain barrier (BBB), and redistribute to secondary targets within brain parenchyma have potential transform diagnosis treatment of a wide range central nervous system disorders. Full understanding pharmacokinetics (PK) these agents, including their for delivering cargo into parenchymal cells, is key priority development numerous therapeutic applications. To date, PK bAbs target transferrin...
Casey, Brian M. MD; Lucas, Michael J. Mclntire, Donald D. PhD; Leveno, Kenneth MD Author Information
Objective. To determine if endothelial monolayer permeability could be altered by serum from preeclampsia (PE). Methods. Confluent normal cells (ECs) were incubated with 20% nonpregnant females, and PE pregnancies or combined antioxidant superoxide dismutase (SOD) for 8 hr. ECs pregnancies. EC barrier function of was accessed measuring electrical resistance (ER) the leakage horseradish peroxidase (HRP) passing through filters. Plasma concentrations IL‐8 lipid peroxides MDA also measured. We...
Thrombin receptors, i.e. proteinase-activated receptors (PARs), are expressed in endothelial cells (ECs) and neutrophils directly affect platelet function thrombosis. Although dysfunction neutrophil activation have been demonstrated women with preeclampsia (PE), the expression regulation of PARs not defined PE. In this study, we measured ECs derived from normal preeclamptic pregnancies. We also examined effects placental factors on PAR these vitro. were isolated umbilical cords (human vein...