A5057367744- Circadian rhythm and melatonin
- Animal Nutrition and Physiology
- Dietary Effects on Health
- Gut microbiota and health
- Photoreceptor and optogenetics research
- Retinal Development and Disorders
- Spaceflight effects on biology
- Reproductive System and Pregnancy
- Neurobiology and Insect Physiology Research
- Biochemical effects in animals
- Adipose Tissue and Metabolism
- Gastrointestinal motility and disorders
- Neuroendocrine regulation and behavior
- Genetics, Aging, and Longevity in Model Organisms
- Animal Genetics and Reproduction
- Glaucoma and retinal disorders
- Stress Responses and Cortisol
- Birth, Development, and Health
- Mast cells and histamine
- Growth Hormone and Insulin-like Growth Factors
- Sleep and Wakefulness Research
- Tryptophan and brain disorders
- Muscle Physiology and Disorders
- Insect and Pesticide Research
- Sleep and related disorders
China Agricultural University
2016-2025
Guangzhou University
2024
South China University of Technology
2024
Xiangtan University
2021
Xi'an Jiaotong University
2018-2020
Chinese Academy of Agricultural Sciences
2017
Institute of Animal Sciences
2017
Xidian University
2016
Feed Research Institute
2013
Shandong Province Animal Husbandry and Veterinary Bureau
2010
Intestinal diseases caused by sleep deprivation (SD) are severe public health threats worldwide. This study focuses on the effect of melatonin intestinal mucosal injury and microbiota dysbiosis in sleep-deprived mice. Mice subjected to SD had significantly elevated norepinephrine levels decreased content plasma. Consistent with decrease levels, we observed a antioxidant ability, down-regulation anti-inflammatory cytokines up-regulation pro-inflammatory mice, which resulted colonic injury,...
Abstract Background Sleep loss is a serious global health concern. Consequences include memory deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can effectively improve cognitive impairment intestinal microbiota disturbances caused by sleep deprivation (SD). The present study further explored the mechanism which exogenous prevents SD-induced impairments. Here, we established fecal transplantation, Aeromonas colonization LPS or butyrate supplementation...
The microbiota-gut-brain axis plays an important role in the development of depression. aim this study was to investigate effects 5-HT on cognitive function, learning and memory induced by chronic unforeseeable mild stress stimulation (CUMS) female mice. CUMS mice TPH2 KO were used study. Lactococcus lactis E001-B-8 fungus powder orally administered with CUMS.We open field test, Morris water maze, tail suspension test sucrose preference examine learning-related behaviours. In addition,...
Abstract Ulcerative colitis (UC) is currently the most common inflammatory bowel disease (IBD). Due to its diverse and complex causes, there no cure at present, researchers are constantly exploring new therapies. In recent years, nano-selenium particle(SeNP) has attracted wide attention due excellent biological activities. Therefore, in this study, for first time, we used a natural polysaccharide, Eucommia ulmoides polysaccharide (EUP), modified SeNP get EUP-SeNP with size of about 170 nm,...
Abstract Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to hypertrophy or double-muscled (DM) phenotype cattle, sheep, dog human. However, there has not been reported significant phenotypes pigs association with mutations. Pigs are an important source meat production, as well serve preferred animal model for the studies human disease. To study impacts mutations on growth pigs, we generated -mutant Meishan no marker via zinc...
Methods of light treatment such as schedule, intensity or illuminance, and color are important factors that influence avian productivity. Therefore, artificial illumination has been widely used in modern poultry husbandry. Although progress had made understanding the effects schedule on growth, growth not clear. In this study, 276 male Arbor Acres broilers were reared under white, red, green, blue lights from light-emitting diode lamps sources. Broilers' productive performance increased...
Objectives: Memory decline caused by insufficient sleep is a critical public health issues and currently lacks effective treatments. This study objective was to explore alleviative effect of melatonin on deprivation (SD)-induced deficiencies in learning memory. Materials Methods: A continuous 72 h SD mouse model, with or without Fer-1 supplementation were established. The changes cognitive function, iron homeostasis, lipid peroxidation intracellular signal pathways mice detected Morris water...
Royal jelly (RJ) is a kind of bee product widely used in cosmetics, medicine and other fields. Not only can RJ regulate the physiological function population, but also play specific biological role many diseases. This paper overviews main active ingredients functional food RJ, including major royal protein, fatty acids, phenols, flavonoids, etc, summarizes maintenance human health, such as regulation immunity, lifespan, memory, digestive system, blood glucose, obesity, antibacterial...
Ferroptosis, an iron-dependent cell death form, has recently been observed in the development of non-alcoholic fatty liver disease (NAFLD).Melatonin (Mel) shows potential benefits for preventing and treating diseases.Whether how Mel ameliorates hepatic ferroptosis NAFLD is not fully understood.Here we established a mouse model induced by long-term high-fat diet (HFD) feeding.We found that treatment ameliorated global metabolic abnormalities inhibited progression mice.Most importantly,...
Environmental (restraint stress) and dietary (high fructose) factors are key triggers for flares of inflammatory bowel disease; however, the mechanisms involved in this phenomenon not fully elucidated. This study aimed to investigate by which restraint stress high fructose damage intestinal mucosal immune barrier. The feces C57BL/6J mice were subjected 16S rRNA untargeted metabolome sequencing, histological structure was analyzed immunohistochemistry immunofluorescence staining. mRNA protein...
The escalating demand for environmentally sustainable and cost-effective adhesives in the wood processing manufacturing sector has prompted exploration into innovative solutions. This study introduces a novel gel adhesive composed of chemically unmodified high-amylose starch (G70, with 68 % amylose content) minimal proportion urea-formaldehyde (UF) (UF/starch = 1:10, w/w). G70/UF demonstrates remarkable capabilities wooden boards under both dry conditions (with shear stress 4.13 ± 0.12 MPa)...
Light pollution is one of the most serious public problems, especially night light. However, effect dim blue light at (dLAN-BL) on cognitive function unclear. In this study, we evaluated effects exposure to dLAN-BL in C57BL/6J mice for 4 consecutive weeks. Our results showed significantly impaired spatial learning and memory increased plasma corticosterone level mice. Consistent with these changes, observed numbers activation microglia levels oxidative stress product MDA hippocampus,...
It is widely known that lack of sleep damages the skin. Therefore, it necessary to explore relationship between deprivation and skin damage find effective treatments. We established a 28-day restriction (SR) mice model simulating continuous long-term loss. found SR would barrier function mice's skin, cause oxidative stress weaken oscillations skin's biological clock, make circadian rhythm Bacteroides disappear. The short-chain fatty acids (SCFA) receptors in was disordered. After melatonin...