A5027075168- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Nanoparticles: synthesis and applications
- Boron and Carbon Nanomaterials Research
- Graphene and Nanomaterials Applications
- MXene and MAX Phase Materials
- Advanced Sensor and Energy Harvesting Materials
- Graphene research and applications
- Nanomaterials for catalytic reactions
- Tissue Engineering and Regenerative Medicine
- Laser-Ablation Synthesis of Nanoparticles
- biodegradable polymer synthesis and properties
- Titanium Alloys Microstructure and Properties
- Orthopaedic implants and arthroplasty
- Antimicrobial agents and applications
- Polymer Surface Interaction Studies
- Catalytic Processes in Materials Science
- Surface Modification and Superhydrophobicity
- Additive Manufacturing and 3D Printing Technologies
- Advanced Materials and Mechanics
- TiO2 Photocatalysis and Solar Cells
- Advanced biosensing and bioanalysis techniques
- Wound Healing and Treatments
- Advanced ceramic materials synthesis
- Adsorption and biosorption for pollutant removal
National University of Science and Technology
2025
National University of Science and Technology
2017-2024
Siberian Branch of the Russian Academy of Sciences
2017-2023
Institute of Clinical and Experimental Lymphology
2020-2023
Institute of Chemical Biology and Fundamental Medicine
2017
Biodegradable nanofibers are extensively employed in different areas of biology and medicine, particularly tissue engineering. The electrospun polycaprolactone (PCL) attracting growing interest due to their good mechanical properties a low-cost structure similar the extracellular matrix. However, unmodified PCL exhibit an inert surface, hindering cell adhesion negatively affecting further fate. employment nanofibrous scaffolds for wound healing requires certain modification surface. In this...
Due to their good mechanical stability compared gelatin, collagen or polyethylene glycol nanofibers and slow degradation rate, biodegradable poly-ε-caprolactone (PCL) are promising material as scaffolds for bone soft-tissue engineering. Here, PCL were prepared by the electrospinning method then subjected surface functionalization aimed at improving biocompatibility bioactivity. For modification, two approaches used: (i) COOH-containing polymer was deposited on using atmospheric pressure...
In recent years, bacteria inactivation during their direct physical contact with surface nanotopography has become one of the promising strategies for fighting infection. Contact-killing ability been reported several nanostructured surfaces, e.g., black silicon, carbon nanotubes, zinc oxide nanorods, and copper nanosheets. Herein, we demonstrate that Gram-negative antibiotic-resistant Escherichia coli (E. coli) are killed as a result destruction while contacting h-BN surfaces. BN films, made...
Utilization of antibacterial components-conjugated nanoparticles (NPs) is emerging as an attractive strategy for combating various pathogens. Herein, we demonstrate that Ag/BN NPs and antibiotic-loaded BN nanoconjugates are promising carriers to fight bacterial fungal infections. Extensive biological tests included two types Gram-positive methicillin-resistant Staphylococcus aureus strains (B8469 MW2), Gram-negative Pseudomonas aeruginosa (ATCC27853 B1307/17), 47 Escherichia coli (including...
The spread of bacterial, fungal, and viral diseases by airborne aerosol flows poses a serious threat to human health, so the development highly effective antibacterial, antifungal antiviral filters protect respiratory system is in great demand. In this study, we developed ZnO-modified polycaprolactone nanofibers (PCL-ZnO) treating nanofiber surface with plasma gaseous mixture Ar/CO2/C2H4 followed deposition ZnO nanoparticles (NPs). structure chemical composition composite fibers were...
We have developed advanced folate bonded to boron nitride (BN) nanocarriers with a high potential for targeted drug delivery. The folic acid (FA) molecules were successfully conjugated BN nanoparticles (BNNPs) in three consecutive stages: (i) FA preactivation by N,N′-dicyclohexylcarbodiimide (DCC), (ii) BNNP modification AgNPs and their further NH2-functionalization l-cysteine, (iii) final conjugation of activated modified BNNPs. To shed light on the FA-BNNPs binding mechanism, detailed...
The scaffolds made of polycaprolactone (PCL) are actively employed in different areas biology and medicine, especially tissue engineering. However, the usage unmodified PCL is significantly restricted by hydrophobicity its surface, due to fact that inert surface hinders adhesion cells cell interactions on surface. In this work, nanofibers modified Ar/CO2/C2H4 plasma depositing active COOH groups amount 0.57 at % were later used for immobilization platelet-rich (PRP). modification enhances...
Novel nanomaterials used for wound healing should have many beneficial properties, including high biological and antibacterial activity. Immobilization of proteins can stimulate cell migration viability, implanted Ag ions provide an antimicrobial effect. However, the ion implantation method, often to introduce a bactericidal element into surface, lead degradation vital proteins. To analyze surface structure nanofibers coated with layer plasma COOH polymer, fibronectin/gentamicin, ions, new...
This study focused on the synthesis and characterization of pure curdlan-chitosan foams (CUR/CS), as well containing Ag nanoparticles (CUR/CS/Ag), their effect skin repair diabetic mice (II type). The layer antibacterial superabsorbent foam provides good oxygenation, prevents bacterial infection, absorbs exudate, forming a soft gel (moist environment). These were prepared from mixture hydrolyzed curdlan chitosan by lyophilization. To enhance properties, an AgNO3 solution was added to...
It is very important to prevent bacterial colonization at the early postoperative stages. There are four major strategies and their corresponding types of antibacterial surfaces specifically designed fight infection: bactericide release, anti-adhesion, pH-sensitive, contact-killing. Herein, we aimed determining efficiency different bactericidal ions revealing possible contribution surface microgalvanic effects arising from a potential difference on heterogeneous surfaces. We considered five...
The COVID-19 pandemic has raised the problem of efficient, low-cost materials enabling effective protection people from viruses transmitted through air or via surfaces. Nanofibers can be a great candidate for efficient filtration due to their structure, although they cannot protect viruses. In this work, we prepared wide range nanofibrous biodegradable samples containing Ag (up 0.6 at.%) and Cu 20.4 exhibiting various wettability. By adjusting magnetron current (0.3 A) implanter voltage (5...