A5063285518- Substance Abuse Treatment and Outcomes
- Cannabis and Cannabinoid Research
- Prenatal Substance Exposure Effects
- Opioid Use Disorder Treatment
- Homelessness and Social Issues
- Psychedelics and Drug Studies
- Neurotransmitter Receptor Influence on Behavior
- Forensic Toxicology and Drug Analysis
- Child and Adolescent Psychosocial and Emotional Development
- Alcohol Consumption and Health Effects
- Medical Research and Treatments
- Pain Management and Opioid Use
- Pharmaceutical Practices and Patient Outcomes
- Misinformation and Its Impacts
- Maternal Mental Health During Pregnancy and Postpartum
- Diabetes Management and Research
- Diabetes and associated disorders
- Alcoholism and Thiamine Deficiency
- Diabetes Treatment and Management
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Schizophrenia research and treatment
- HIV, Drug Use, Sexual Risk
- Emergency and Acute Care Studies
- Poisoning and overdose treatments
- Cardiac Arrest and Resuscitation
The University of Melbourne
2016-2025
St Vincent's Health
2005-2025
St Vincent's Hospital
2016-2025
Royal Women's Hospital
2017-2024
The Arrhythmia Institute
2019-2024
St Vincent's Clinic
2022-2023
St. Vincent's Hospital
2021
Saint Vincent's Catholic Medical Center
2021
St. Vincent's Birmingham
2015-2021
St Vincent’s Private Hospital Sydney
2020
ABSTRACT Aim To determine whether adolescent alcohol use and/or other health risk behaviour predisposes to dependence in young adulthood. Design Seven‐wave cohort study over 6 years. Participant A community sample of almost two thousand individuals followed from ages 14–15 20–21 Outcome measure Diagnostic and Statistical Manual volume IV (DSM‐IV) participants aged years drinking three or more times a week. Findings Approximately 90% consumed by age 20 years, 4.7% fulfilling DSM‐IV criteria....
To compare the occurrence of behaviours occurring under influence alcohol in 16-17-year-olds and determine associated risk factors for different behaviours.Cross-sectional survey administered by laptop computers secondary schools across state Victoria, Australia. MEASUREMENT/FINDINGS: The participation rate was 79%. Seventy per cent participants drank alcohol; 17% drinkers reported alcohol-related violence (accidents or injuries) 15% problems relating to sex (having later regretting it...
The aim of the current study was to review drug harms as they occur in Australia using Multi-criteria Decision Analysis (MCDA) methodology adopted earlier studies other jurisdictions.A facilitated workshop with 25 experts from across Australia, held score 22 drugs on 16 criteria: 9 related that a produces individual and 7 others. Participants were guided by facilitators through principles MCDA. In open discussion, each scored criterion. criteria then weighted process swing weighting. Scoring...
More than half of patients with alcohol use disorder who receive inpatient withdrawal treatment relapse within weeks discharge, hampering subsequent uptake and effectiveness psychological pharmacologic interventions. Cognitive bias modification (CBM) improves outcomes after rehabilitation, but the efficacy delivering CBM during has not yet been established.To test hypothesis that would increase likelihood abstaining from 2 following discharge treatment.In a randomized clinical trial, 950 in...
Chapter 2: Screening and assessment for unhealthy alcohol use appropriate interventions should be implemented in general practice (Level A), hospitals B), emergency departments community health welfare settings C). Quantity-frequency measures can detect consumption that exceeds levels the current Australian guidelines B). The Alcohol Use Disorders Identification Test (AUDIT) is most effective screening tool recommended primary care hospital settings. For community, AUDIT-C a suitable...
Objective We identify drinking styles that place teens at greatest risk of later alcohol use disorders (AUD). Design Population-based cohort study. Setting Victoria, Australia. Participants A representative sample 1943 adolescents living in Victoria 1992. Outcome measures Teen was assessed 6 monthly intervals (5 waves) between mean ages 14.9 and 17.4 years summarised across waves as none, one, or two more of: (1) frequent (3+ days the past week), (2) loss control over (difficulty stopping,...
The medical use of psychedelic substances (e.g. psilocybin, ayahuasca, lysergic acid diethylamide and 3,4-methylenedioxymethamphetamine) is attracting renewed interest, driven by a pressing need for research development novel therapies psychiatric disorders, as well promising results contemporary studies. In this Viewpoint, we reflect upon the 'Clinical Memorandum on Psychedelics' recently released Royal Australian New Zealand College Psychiatrists note subsequent developments including...
Key Clinical Message This case suggests using dual orexin receptor antagonists to treat alcohol use disorder and comorbid sleep disorders may be effective, commencing treatment in withdrawal continuing it prevent relapse. Abstract Effective medications for the of are limited. is partially due heterogenous nature symptomatology associated with abundance presenting comorbidities. One common, often overlooked, symptom that occurs during disruption. Here, we report a study participant insomnia....
Introduction In response to the 2021 Royal Commission into Victoria’s Mental Health System, Victorian government established six purpose-built Alcohol and Other Drug (MHAOD) emergency department (ED) Hubs. This study evaluates MHAOD Hub at St Vincent’s Hospital Melbourne (SVHM), which opened in March 2022 as metropolitan Melbourne’s first multidisciplinary or integrated Emergency Department. Methods retrospective analysis covers patient admissions from June 2024, documenting demographics,...
Abstract Background and aims The use of amphetamines (including amphetamine methamphetamine) has been consistently associated with mental health difficulties; however, the direction potential causal relationships not yet established. This study aimed to assess between illicit difficulties across adolescence young adulthood. Design Observational four population‐level cohorts participating in Monitoring Illicit Substance Use (MISUse) Consortium. Setting Australia New Zealand. Participants A...
Abstract Background and aims Approach bias modification (ApBM) targeting alcohol approach has been previously shown to reduce likelihood of relapse during the first 2 weeks following inpatient withdrawal treatment (IWT). We tested whether ApBM’s effects endure for a longer period by analysing use outcomes 3, 6 12 months post‐discharge. Design A double‐blind, sham‐controlled randomized controlled trial. Setting Four IWT units in Melbourne, Australia. Participants Three hundred patients (173...
Medicinal cannabis was legalised in Australia November 2016. By August 2022, there were 5284 specialist physician and general practitioner (GP) prescribers who submitted Special Access Scheme (SAS) applications to the Therapeutic Goods Administration (TGA) for provision of medicinal prescriptions their patients. In this article we examine impact delivery publicly available clinical guidance documents, education prescribers, establishment TGA online portal, launching clinics on number...
The use of cannabis for medicinal purposes has increased globally over the past decade since patient access to been legislated across jurisdictions in Europe, United Kingdom, States, Canada, and Australia. Yet, evidence relating effect medical on management symptoms a suite conditions is only just emerging. Although there considerable engagement from many stakeholders add base through randomized controlled trials, gaps literature remain. Data real-world reported sources can provide...
Objective We sought to explore physician perspectives on the prescribing of cannabinoids patients gain a deeper understanding issues faced by prescriber and public health advisors in rollout medicinal cannabis. Design A thematic qualitative analysis 21 in-depth interviews was undertaken narrative policy practice cannabis prescribing. The used Diffusion Innovations (DoI) theoretical framework model conceptualisation Australian context. Setting Informants from states territories Victoria, New...
Progress in promoting mental health, preventing illness, and improving care for people affected by illness is unlikely to occur if efforts remain separated from existing public health programs the principles of action. Experts met recently discuss integrating strategies south east Asia, especially low- middle-income countries. Areas research identified as high priority were: 1) into perinatal care; 2) providing culturally-adjusted support carers with physical disorders; 3) using digital...
A defect in skeletal muscle mitochondrial metabolism develops patients with chronic renal failure on haemodialysis. Treatment carnitine, a compound essential for normal function, has been suggested to have significant benefits such patients, so we carried out study see if carnitine acts by improving bioenergetics and function.In phase II randomised double-blind trial, end-stage disease received placebo or intravenous L-carnitine (20 mg/kg dry body weight three times weekly after...
Abstract Alcohol use disorder (AUD) and methamphetamine (MUD) are prevalent have high adverse impacts on both the individual society. Current treatment strategies for these disorders ineffective at a population level. Lorcaserin, 5‐HT 2C receptor agonist, has shown potential reducing symptoms of substance disorder. This pilot study (initiated prior to market withdrawal) examined feasibility safety lorcaserin in people undergoing residential detoxification AUD MUD. was an open label where...