A5038354814- Advancements in Transdermal Drug Delivery
- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Cannabis and Cannabinoid Research
- Drug Solubulity and Delivery Systems
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Dermatology and Skin Diseases
- Immunodeficiency and Autoimmune Disorders
- Surfactants and Colloidal Systems
- Lipid Membrane Structure and Behavior
- Antioxidant Activity and Oxidative Stress
- Gastrointestinal disorders and treatments
- Diet, Metabolism, and Disease
- Celiac Disease Research and Management
- Retinal Diseases and Treatments
- Toxin Mechanisms and Immunotoxins
- Immunotherapy and Immune Responses
- Insect Pest Control Strategies
- Pharmaceutical studies and practices
- Pomegranate: compositions and health benefits
Universidade do Porto
2023-2024
Institute of Natural Fibres and Medicinal Plants
2024
Medical University of Vienna
2024
University of Hong Kong
2024
Jahangirnagar University
2024
Ningbo University
2024
Institute of Human Genetics
2020-2023
Polish Academy of Sciences
2020-2023
Bydgoszcz University of Science and Technology
2023
University of Coimbra
2018-2022
In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1,2-epoxide and glycerol monostearate (Lim-SLNs), stabilized Poloxamer® 188 in aqueous dispersion to modify the release profile of loaded monoterpene derivative. We also evaluated role SLNs peroxidation cytotoxicity spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin (the HaCaT line). For viability assay, colorimetric...
Glycerol monostearate solid lipid nanoparticles (SLN) were produced by hot high-pressure homogenization technique to load alpha-pinene, citral, geraniol or limonene. SLN composed of 1 wt.% monoterpene, 4 Imwitor® 900K as a and 2.5 Poloxamer188 surfactant. Empty consisted 5 Poloxamer188. The mean particles size (Z-Ave) polydispersity index (PDI) analyzed dynamic light scattering (DLS), while the zeta potential (ZP) each formulation measured electrophoretic scattering. LUMiSizer® was applied...
The encapsulation of bicyclic monoterpene α-pinene into solid lipid nanoparticles (SLN) is reported using experimental factorial design, followed by high-end dispersion analyzer LUMiSizer®. This equipment allows the characterization α-pinene-loaded SLN instability phenomena (e.g., sedimentation, flotation or coagulation), as well determination velocity distribution in centrifugal field and particle size distribution. In this work, were produced hot high-pressure homogenization technique....
Nowadays, a combinatorial drug delivery system that simultaneously transports two or more drugs to the targeted site in human body, also recognized as dual-drugs system, represents promising strategy overcome resistance. Solid lipid nanoparticles loaded with clotrimazole (CLZ) and alphalipolic acid (ALA), considered an effective agent reduction of reactive oxygen species, can enhance anti-infective immunity being proposed non-toxic mainly non-allergic system. In this study, uncoated cationic...
The high interest in non-psychoactive cannabidiol increases the need for efficient and straightforward (CBD) extraction methods. research aimed to compare simple methods of cannabinoid that do not require advanced laboratory equipment. This work assesses content total CBD Δ9-tetrahydrocannabinol (Δ9-THC) popular solvents such as water ethanol extracts. Hemp raw material was analyzed with Gas Chromatography a Flame Ionization Detector (GC-FID), while extracts were tested by High-Performance...
Solid Lipid Nanoparticles (SLN) and Nanostructured Carriers (NLC) are receiving increasing interest as an approach to encapsulate natural extracts increase the physicochemical stability of bioactives. Cannabis extract-derived cannabidiol (CBD) has potent therapeutic properties, including anti-inflammatory, antioxidant, neuroprotective properties. In this work, characterization was carried out after producing Compritol-based nanoparticles (cSLN or cNLC) loaded with CBD. Then, determination...
Three-dimensional (3D) printing technologies are manufacturing approaches with widespread use in industry (e.g. automotive, automobile, pharmaceutical industries). With regard to its industry, 3D is demonstrating be of added value attributed the possibility tailored products, namely personalized medical devices, such as implants and other dosage forms. However, approval first 3D-printed drug-product 2015, a new perspective has arisen, i.e. this technology produce solid oral forms exhibiting...