A5072472271- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Essential Oils and Antimicrobial Activity
- Nanoparticle-Based Drug Delivery
- Lipid Membrane Structure and Behavior
- Bee Products Chemical Analysis
- Drug Solubulity and Delivery Systems
- Surfactants and Colloidal Systems
- RNA Interference and Gene Delivery
- Phytochemicals and Antioxidant Activities
- Nanoparticles: synthesis and applications
- Ocular Surface and Contact Lens
- Graphene and Nanomaterials Applications
- Dermatology and Skin Diseases
- Proteins in Food Systems
- biodegradable polymer synthesis and properties
- Wound Healing and Treatments
- Microencapsulation and Drying Processes
- Electrospun Nanofibers in Biomedical Applications
- Skin Protection and Aging
- Hydrogels: synthesis, properties, applications
- Research on Leishmaniasis Studies
- Nanoplatforms for cancer theranostics
- Nanocomposite Films for Food Packaging
- Analytical Chemistry and Chromatography
University College Dublin
2024-2025
Universidade do Porto
2004-2024
Rede de Química e Tecnologia
2016-2024
Medical University of Vienna
2024
University of Hong Kong
2024
Universitat de Barcelona
2019-2024
Ningbo University
2024
University of Minho
2018-2023
University of Coimbra
2014-2023
Universidade Tiradentes
2022
To understand the effect of physical state and composition lipid materials on formation performance nanocarriers, three types carriers namely, solid nanoparticles (SLN), nanostructured (NLC) nanoemulsions (LNE) were prepared compared. Quercetin was used as a model nutraceutical compound to evaluate potency these nanocarriers increase bioaccessibility. Among developed quercetin loaded free NLC showed smallest particle size (∼34 47 nm) compared SLN (∼103 127 LNE (∼82 83 nm). Encapsulation...
Lipids and lipid nanoparticles are extensively employed as oral-delivery systems for drugs other active ingredients. These have been exploited many features in the field of pharmaceutical technology. usually enhance drug absorption gastrointestinal tract (GIT), when formulated nanoparticles, these molecules improve mucosal adhesion due to small particle size increasing their GIT residence time. In addition, may also protect loaded from chemical enzymatic degradation gradually release matrix...
Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's disease (AD) but its inherent instability limits bioavailability and effectiveness. We found that EGCG displayed increased stability when formulated as dual-drug loaded PEGylated PLGA nanoparticles (EGCG/AA NPs). Oral administration EGCG/AA NPs in mice resulted accumulation all major organs, including the brain. Pharmacokinetic comparison plasma brain following oral free or showed that, whilst both cases initial...
Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown be fully effective. In order solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could a suitable solution increase drug's action on the target site as well decrease adverse effects. For these reason, Memantine was loaded in biodegradable PLGA nanoparticles, produced by double emulsion method and surface-coated with polyethylene glycol. MEM–PEG–PLGA (NPs) were aimed blood–brain barrier (BBB) upon...
Polymer hydrogels have been suggested as dressing materials for the treatment of cutaneous wounds and tissue revitalization. In this work, we report development a hydrogel composed natural polymers (sodium alginate gelatin) silver nanoparticles (AgNPs) with recognized antimicrobial activity healing lesions. For hydrogel, different ratios sodium gelatin tested, while concentrations AgNO3 precursor (1.0, 2.0, 4.0 mM) were assayed production AgNPs. The obtained AgNPs exhibited characteristic...