A5003028700- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Alzheimer's disease research and treatments
- Nanoparticle-Based Drug Delivery
- Ocular Surface and Contact Lens
- RNA Interference and Gene Delivery
- Cholinesterase and Neurodegenerative Diseases
- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Dermatology and Skin Diseases
- Endodontics and Root Canal Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Antimicrobial agents and applications
- Lipid Membrane Structure and Behavior
- Tryptophan and brain disorders
- Natural Antidiabetic Agents Studies
- Supramolecular Self-Assembly in Materials
- Curcumin's Biomedical Applications
- Circadian rhythm and melatonin
- Cutaneous Melanoma Detection and Management
- Computational Drug Discovery Methods
- Retinal Diseases and Treatments
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Surfactants and Colloidal Systems
Universitat de Barcelona
2016-2025
Institute of Advanced Chemistry of Catalonia
2022-2025
Institut de Nanociència i Nanotecnologia de la Universitat de Barcelona
2016-2025
Biomedical Research Networking Center on Neurodegenerative Diseases
2017-2025
Centro de Investigación Biomédica en Red
2025
Netherlands Metabolomics Centre
2022-2023
Leiden University Medical Center
2022-2023
Instituto de Salud Carlos III
2018-2023
University of Alicante
2023
University of Coimbra
2019-2021
Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown be fully effective. In order solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could a suitable solution increase drug's action on the target site as well decrease adverse effects. For these reason, Memantine was loaded in biodegradable PLGA nanoparticles, produced by double emulsion method and surface-coated with polyethylene glycol. MEM–PEG–PLGA (NPs) were aimed blood–brain barrier (BBB) upon...
Polymer hydrogels have been suggested as dressing materials for the treatment of cutaneous wounds and tissue revitalization. In this work, we report development a hydrogel composed natural polymers (sodium alginate gelatin) silver nanoparticles (AgNPs) with recognized antimicrobial activity healing lesions. For hydrogel, different ratios sodium gelatin tested, while concentrations AgNO3 precursor (1.0, 2.0, 4.0 mM) were assayed production AgNPs. The obtained AgNPs exhibited characteristic...
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND) diseases. Nanomedicine can overcome restrictions CNS delivery imposed by blood–brain barrier, and thus be instrumental in preclinical discovery therapeutic ND Polymeric nanoparticles (PNPs) have shown great potential versatility encapsulate several compounds simultaneously controlled drug-delivery systems target them deepest brain regions. Here, we critically review recent advances development drugs...
Abstract Glaucoma is a multifactorial neurodegenerative disease associated with retinal ganglion cells (RGC) loss. Increasing reports of similarities in glaucoma and other conditions have led to speculation that therapies for brain disorders may also potential as therapies. Memantine an N ‐methyl‐ d ‐aspartate (NMDA) antagonist approved Alzheimer's treatment. Glutamate‐induced excitotoxicity implicated NMDA receptor antagonism advocated strategy RGC preservation. This study describes the...
Purpose: The anticancer potential of indomethacin and other nonsteroidal anti-inflammatory drugs (NSAIDs) in vitro, vivo, clinical trials is well known widely reported the literature, along with their side effects, which are mainly observed gastrointestinal tract. Here, we present a strategy for application old drug as an agent by encapsulating it nanostructured lipid carriers (NLC). We describe production method IND-NLC, physicochemical parameters, results antiproliferative activity against...