- Quantum Dots Synthesis And Properties
- Advanced biosensing and bioanalysis techniques
- Nanocluster Synthesis and Applications
- Chemical Synthesis and Analysis
- Photodynamic Therapy Research Studies
- Lanthanide and Transition Metal Complexes
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Chalcogenide Semiconductor Thin Films
- Synthesis and Biological Evaluation
- Carbon and Quantum Dots Applications
- Catalytic C–H Functionalization Methods
- Nanoparticles: synthesis and applications
- Supramolecular Self-Assembly in Materials
- Graphene and Nanomaterials Applications
- Mosquito-borne diseases and control
- Bone Tissue Engineering Materials
- Molecular Sensors and Ion Detection
- Antifungal resistance and susceptibility
- biodegradable polymer synthesis and properties
- Biosensors and Analytical Detection
- Lipid Membrane Structure and Behavior
- Synthesis of heterocyclic compounds
- Advanced Biosensing Techniques and Applications
Universidade Federal de Pernambuco
2015-2024
University of Aveiro
2023-2024
Universidade Federal do Maranhão
2024
Union des Industries Ferroviaires Européennes
2020
University of Minho
2007-2018
Clinical Academic Center of Braga
2015
Rede de Química e Tecnologia
2009-2014
Universidade do Porto
2009-2011
The development of multifunctional materials for bone tissue repair has attracted researchers' interest. Several classes have been studied and optimized this aim, such as implants based on metals, ceramic, glasses, composites. Among these is hydroxyapatite (HAp), a popular scaffold used the main constituent several biomaterials. HAp presents good biocompatibility, osteoconduction, non-toxicity, porosity, adequate mechanical properties. Nevertheless, to improve its properties or add novel...
Water contamination represents a significant ecological impact with global consequences, contributing to water scarcity worldwide. The presence of several pollutants, including heavy metals, pharmaceuticals, pesticides, and pathogens, in resources underscores pressing concern, prompting the European Union (EU) establish Watch List monitor level these substances. Nowadays, standard methods used detect quantify contaminants are mainly liquid or gas chromatography coupled mass spectrometry...
As organizações públicas enfrentam pressões crescentes por mais eficiência e transparência, sobrecarregadas dentro de um contexto grande volume dados, mudanças constantes situações adversas. Esse cenário exige das maior agilidade na tomada decisão investimento em soluções tecnológicas que auxiliem a gestão pública ser eficiente transparente. O objetivo deste estudo foi levantar as evidências quanto utilização painéis indicadores, tipo Business Intelligence (BI), no da brasileira, destacando...
Este artigo tem por objetivo analisar a epidemiologia das internações esquistossomose no Brasil período de 2014 2024. Trata-se uma pesquisa descritiva, transversal e epidemiológica. Os dados acerca foram obtidos através do Sistema Informações Hospitalares Departamento Informática Único Saúde (SIH/DATASUS), considerando o As variáveis analisadas incluíram sexo, faixa etária, raça, número ano. No analisado, registradas 1.813 Brasil. A análise dos revela um padrão geográfico demográfico...
Quantum dots (QDs) are semiconductor nanocrystals, which present unique photophysical properties, enabling their application as new fluorescent platforms for biomedical sciences.Colloidal QDs end-capped with organic or inorganic compounds, not only to prevent agglomeration but also provide reaction sites the attachment of targeting (bio)molecules, nanoparticles other interfaces, specific biological purposes.The (bio)conjugation can involve non-covalent covalent interactions, be accomplished...
Supramolecular hydrogels rely on small molecules that self-assemble in water as a result of the cooperative effect several relatively weak intermolecular interactions. Peptide-based low molecular weight hydrogelators have attracted enormous interest owing to simplicity combined with versatility and biocompatibility peptides. In this work, naproxen, well known non-steroidal anti-inflammatory drug, was N-conjugated various dehydrodipeptides give aromatic peptide amphiphiles resist proteolysis....
Abstract Several N ‐acyl‐β‐hydroxyamino acids were prepared and treated with di‐ tert ‐butyl dicarbonate in the presence of 4‐(dimethylamino)pyridine, followed by treatment , N′ ‐tetramethylguanidine to give corresponding ‐acyldehydroamino good high yields. These then I 2 /K CO 3 1,8‐diazabicyclo[5.4.0]undec‐7‐ene. The methyl esters ‐acyldehydroaminobutyric acid gave substituted oxazoles ‐acyldehydrophenylalanines 5‐phenyloxazole derivatives low moderate yields together...
Abstract We have developed a modification of our previously reported high‐yielding method for the synthesis N , ‐diacyldehydroamino acid derivatives to prepare ‐monoprotected dehydroamino acids and dehydrodipeptides. Thus, several dehydroalanine, dehydroaminobutyric dehydrophenylalanine been prepared by treating corresponding L ‐serine, ‐threonine D ‐3‐phenylserine ( threo ‐type) with 1 equiv. di‐ tert ‐butyl dicarbonate 4‐(dimethylamino)pyridine. The reaction proceeded initial formation an...
Contamination of aquatic resources with antibiotics poses a threat to the environment and human health, leading increase antimicrobial resistance, which is predicted be cause death by 2050. Conventional water treatment systems are often ineffective in removing implementation more efficient methods, such as photocatalysis, an important step forward mitigate this problem. Nanomaterials have shown efficiency photocatalysts degradation organic pollutants, due their high surface area/volume...
Magnetic resonance imaging (MRI) is a powerful non-invasive diagnostic tool that enables distinguishing healthy from pathological tissues, with high anatomical detail. Nevertheless, MRI quite limited in the investigation of molecular/cellular biochemical events, which can be reached by fluorescence-based techniques. Thus, we developed bimodal nanosystems consisting hydrophilic quantum dots (QDs) directly conjugated to Gd(III)-DO3A monoamide chelates, Gd(III)-DOTA derivative, allowing for...
Silver selenide quantum dots in aqueous suspension for amplifying the infrared signature of dye molecules and multivariate enhancement factor.
Abstract Synthetic cathinones are new psychoactive substances that a menace to public health worldwide and real forensic challenge. Given the recent changes in Brazilian legislation bans generic structure of these substances, workflow drug analysis has opportunity speed up arrests by loco screening analysis. This preliminary study investigated use portable Raman spectrometer chemometrics for fast, direct, non‐destructive presumptive identification three synthetic seized packages confirmatory...
We have proposed recently that the DO3A-N-α-(amino)propionate chelator and its amide conjugates are leads to targeted, high relaxivity, safe contrast agents for magnetic resonance imaging. In this work we illustrate further expeditious nature robustness of synthetic methodologies developed by preparing DO3A-N-(α-pyrenebutanamido)propionate chelator. Its Gd(3+) chelate retains optimized water exchange, stability inertness parent complex. The pyrene moiety imparts concentration-dependent...