A5001636365- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- Marine Invertebrate Physiology and Ecology
- Ion channel regulation and function
- Insect and Pesticide Research
- Healthcare and Venom Research
- Amphibian and Reptile Biology
- Nicotinic Acetylcholine Receptors Study
- Entomological Studies and Ecology
- Animal Ecology and Behavior Studies
- Mosquito-borne diseases and control
- Dermatological diseases and infestations
- Turtle Biology and Conservation
- Biochemical and Structural Characterization
- Erythrocyte Function and Pathophysiology
- Poisoning and overdose treatments
- Traumatic Ocular and Foreign Body Injuries
- Yersinia bacterium, plague, ectoparasites research
- Leech Biology and Applications
- Toxin Mechanisms and Immunotoxins
- Bee Products Chemical Analysis
- Vector-borne infectious diseases
- Peripheral Artery Disease Management
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
University of Buenos Aires
2014-2024
Administración Nacional de Laboratorios e Institutos de Salud
2012-2024
Ministerio de Salud
2013-2024
Western University of Health Sciences
2020
Universidad Nacional de Córdoba
2020
Hospital Muñiz
2020
Bernardino Rivadavia Natural Sciences Museum
2020
Universidad Nacional de La Plata
2020
National University of Tucumán
2020
Fundación Centro de Estudios Infectológicos
2020
ABSTRACT The efficacy of vaccination with Toxoplasma gondii recombinant GRA4 (rGRA4) and ROP2 (rRPO2) proteins a mix both combined alum were evaluated in C57BL/6 C3H mice. In mice, rGRA4 rGRA4-rROP2 immunizations generated similar levels immunoglobulin G1 (IgG1) IgG2a isotypes against GRA4, whereas rROP2 the induced predominant IgG1 production ROP2. All groups vaccinated mice exhibited higher than IgG2a. rGRA4-stimulated splenocytes from produced primarily gamma interferon while those...
Deaths by venomous animals are medical emergencies that can lead to death and thus constitute sanitary problems in some regions of the world. In South America, accidents these a common problem especially warm, tropical or subtropical regions, related with rural work several countries. Argentina is located extreme America minor part continental surface where most happen. However, big cities center country, no relation work, scorpionism, mostly due synanthropic facultative parthenogenetic...
Envenomation by coral snakes (Micrurus sp.) is one of the most dangerous injuries in America and it considered as a serious medical emergency, however bites these appear to be rare. We analyzed epidemiological data, clinical signs antivenom use Argentina during period between 1979-2003. During this study 46 non-fatal Micrurus were reported. The majority cases men from 31 40 years old. Bites occurred primarily spring summer. Most reported northeast northwest provinces country. mostly located...
Micrurus snakes (coral snakes) may produce severe envenomation that can lead to death by peripheral respiratory paralysis. Only few laboratories specific antivenoms, and despite the cross‐reactivity found in some species venoms, treatment is not always effective. To test two therapeutic antivenoms against venom of four from Southern America, North South Central determination lethal potency study biochemical immunochemical characteristics, neutralizing activity both were studied. American...
Journal Article Epidemiology of snakebite and use antivenom in Argentina Get access Jorge Adrián Dolab, Dolab aDepartamento de Vacunas y Sueros, INPB-ANLIS 'Dr Carlos G. Malbrán', Ministerio Salud, Search for other works by this author on: Oxford Academic PubMed Google Scholar Adolfo Rafael Roodt, Roodt bDirección Nacional Determinantes la Salud e Investigación, ArgentinacLaboratorio Toxinopatología, Centro Patología Experimental Aplicada, Facultad Medicina, Universidad Buenos Aires, Ernesto...
The first example of a new sub-family toxins (alpha-KTx20.1) from the scorpion Tityus trivittatus was purified, sequenced and characterized physiologically. It has 29 amino acid residues, three disulfide bridges assumed to adopt cysteine-stabilized alpha/beta scaffold with pI value 8.98. sequence identities all other known alpha-KTx are less than 40%. Its effects were verified using seven different cloned K(+) channels (vertebrate Kv1.1-1.5, Shaker IR hERG) expressed in Xenopus leavis...