Weiping Xu

ORCID: 0000-0003-2611-0550
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About
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Research Areas
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Nanoparticle-Based Drug Delivery
  • Effects and risks of endocrine disrupting chemicals
  • Diet and metabolism studies
  • RNA modifications and cancer
  • Nanocluster Synthesis and Applications
  • Nanoparticles: synthesis and applications
  • Breast Lesions and Carcinomas
  • Epigenetics and DNA Methylation
  • Autophagy in Disease and Therapy
  • Breast Cancer Treatment Studies
  • Bone Tissue Engineering Materials
  • Cancer-related gene regulation
  • Quantum Dots Synthesis And Properties
  • Wastewater Treatment and Nitrogen Removal
  • Diet, Metabolism, and Disease
  • Cancer and Skin Lesions
  • Graphene and Nanomaterials Applications
  • Perovskite Materials and Applications
  • Pharmacological Effects of Natural Compounds
  • Electrochemical sensors and biosensors
  • Cytokine Signaling Pathways and Interactions
  • Solid-state spectroscopy and crystallography

University of Science and Technology of China
2010-2025

Southwest University of Political Science & Law
2025

Anhui University of Traditional Chinese Medicine
2017-2023

Institute of Intelligent Machines
2023

Chinese Academy of Sciences
2023

Hefei Institutes of Physical Science
2023

Nanjing Traditional Chinese Medicine Hospital
2021

Anhui Provincial Hospital
2006-2020

State Grid Corporation of China (China)
2020

Hefei University of Technology
2019

Uniform and water-soluble Ag@reduced graphene oxide (Ag@rGO) nanocomposites can be prepared by a facile approach in the absence of additional reductants, which display much better antibacterial properties than that pure silver nanoparticles synthesized microwave irradiation, an equivalent effect comparison with general drug ampicillin. Their skin irritation tests use rat models are taken order to explore toxicity this nanocomposite, confirm no oedema or erythema appears on injured after...

10.1039/c0jm03376f article EN Journal of Materials Chemistry 2011-01-01

Abstract The exploration of lead‐free halide perovskite nanocrystals (NCs) with intriguing optical properties is highly desirable owing to the toxicity and instability lead NCs. Here, a new kind uniform double Cs 2 NaBiCl 6 NCs are reported as versatile hosts accommodate ionic dopants for improving especially photoluminescence (PL). In contrast low deep‐blue PL quantum yield only 1.7% as‐synthesized pristine NCs, can be impressively regulated enhanced via doping Ag + , Mn 2+ or Eu 3+ ions in...

10.1002/adom.201901919 article EN Advanced Optical Materials 2020-02-17

Abstract Commensal bacteria are crucial to maintain immune homeostasis in mucosal tissues and disturbances their ecology can affect disease susceptibility. Here, we report evidence that commensal shape the efficiency of surveillance tissues. Antibiotic-treated (Abt) mice were more susceptible development engrafted B16/F10 melanoma Lewis lung carcinoma, exhibiting a shortened mean survival time with numerous larger tumor foci lungs. The defective antitumor response Abt was independent...

10.1158/0008-5472.can-13-2462 article EN Cancer Research 2014-06-20

Translating the unique characteristics of individual nanoscale components into macroscopic materials such as membranes or sheets still remains a challenge, engineering these structures often compromises their intrinsic properties. Here, we demonstrate that highly active carbonaceous nanofibers (CNFs), which are prepared through template-directed hydrothermal carbonization process, can be used versatile scaffold for constructing multifunctional membranes. In order to broad applicability CNF...

10.1021/nn202789f article EN ACS Nano 2011-09-27

Abstract Lead halide perovskites have gained extensive attention in the photodetectors (PDs) field, but problems of intrinsic toxicity and poor stability still hamper their practical applications. Furthermore, ultraviolet (UV) PDs rarely been explored due to challenges, including lack suitable materials costly complicated fabrication processes. In order solve above problems, herein it is reported a novel all‐inorganic lead‐free CsAg 2 I 3 single crystal (SC) with pure phase high quality....

10.1002/adfm.202202894 article EN Advanced Functional Materials 2022-04-20

Abstract Herein, a kind of novel monocomponent hydrophilic and paramagnetic manganese(II) oxide nanocrystal is prepared in polar solution by one‐pot microwave‐assisted synthesis. This can be taken up efficiently to serve as an excellent T 1 magnetic resonance imaging (MRI) contrast agent with enhanced r value 0.81 mM −1 s . The key the success this method that no additional capping agents are required for coating onto surface via ligand exchange, facilitating research their intrinsic...

10.1002/adfm.201202233 article EN Advanced Functional Materials 2012-10-26

Diethylhexyl phthalate (DEHP) is suspected to be an inevitable factor related metabolic disease. Our previous study demonstrated that excess DEHP could exacerbate non-alcoholic fatty liver disease (NAFLD) in SD rats. Addressing the terra incognita DEHP-induced dysfunction, this used HepG2 cells investigate potential mechanisms involved toxicity vitro. The were established lipid overload model with oleic acid and BSA, then exposed different concentrations (5, 10, 25, 50, 100 μmol/l DEHP) of...

10.1080/15376516.2016.1273427 article EN Toxicology Mechanisms and Methods 2016-12-20

Currently, developing new types of simple and effective detection methods phthalate plasticizers (PAEs) remains challenging, whereas the process traditional instruments is tedious laborious. With regard to PAEs, their intrinsically poor Raman activity very low affinity onto metallic surfaces seriously obstruct realization directly surface-enhanced spectroscopy (SERS) detection. Here, a dual-mode sensing system with specific trace butyl benzyl (BBP, one PAEs) was demonstrated by constructing...

10.1021/acsanm.9b00258 article EN ACS Applied Nano Materials 2019-04-30

Purpose: Pachyman, derived from Poria cocos, has been used to treat gouty arthritis (GA) for thousands of years, although its precise role and mechanisms remain unclear. Herein, we investigate the therapeutic effects pachyman on GA explore their underlying mechanisms. Methods: Network pharmacology experimental methods were employed against GA. The protein-protein interaction network shared targets between gout was constructed. Furthermore, elucidated functions Subsequently, validated...

10.2174/0113862073330896241211155436 article EN Combinatorial Chemistry & High Throughput Screening 2025-01-22

Point-wise suturing is the standard method for ensuring that patches effectively perform mechanically supportive functions in tissue repair. However, stress concentrations around suture holes can compromise mechanical stability of patches. In this study, we develop a suturable hydrogel patch with flaw-tolerance capabilities by leveraging multiscale deconcentration, inspired natural silk. This design mitigates concentration across two scales through synergistic integration nanoscale...

10.1021/acsnano.4c17122 article EN ACS Nano 2025-03-16

ZnO nanorods/Au nanocomposites with Au nanocrystals growing at tips of nanorods or located along the surface can be synthesized via a facile low-cost solution method. The number nanoparticles grown on controlled by tuning molar ratio to HAuCl4; thus, ZnO/Au heterostructures displayed tunable UV and visible emission intensity. cytotoxic studies two different cell lines (CHO cells Hela cells) indicated that hybrid are biologically nontoxic. MTT assays these consistent, showing nanomaterials...

10.1021/jp804547e article EN The Journal of Physical Chemistry C 2008-11-21

Abstract Multicomponent Ni 7 Co 3 alloy–Au nanorings can be facilely synthesized at room temperature using metallic alloy as both reducing agent and sacrificial template in water. These novel hybrid are well biocompatible due to coating with poly(vinylpyrrolidone) gold nanoparticles. When increasing the molar ratio of salt from 1:1 5:1, number nanoparticles loaded on surface were found decreased, their morphology was transformed rod particle, remaining ring‐like assemblies. Their saturation...

10.1002/adfm.201001201 article EN Advanced Functional Materials 2010-10-07

Abstract Induction of autophagy is a common response cells upon exposure to nanomaterials and represents both safety concern an application niche for engineered nanomaterials. Herein, it reported that the magnetic property autophagy‐inducing activity Ni–Co alloy nanocrystal (NC) assemblies can be differentially “tuned” through altering material composition. A series NC assemblies, composed nanoparticles (NPs) with size about 30 nm, quickly synthesized under microwave irradiation in aqueous...

10.1002/adfm.201203767 article EN Advanced Functional Materials 2013-06-25

Melatonin is supposed to be an effective hepatoprotective agent. The effects and mechanisms of melatonin on alcoholic fatty liver (AFL) have not been well explored. aim this study was investigate the preventive therapeutic alcohol-induced rats. AFL rats were induced by intragastric infusion alcohol plus a high-fat diet for 6 weeks, (10, 20, 40 mg/kg) administered gastric perfusion. We also established acid overload cell model in HepG2 cells effect AMP-activated protein kinase (AMPK)...

10.1093/alcalc/agv126 article EN cc-by Alcohol and Alcoholism 2015-11-11

Upconversional core-shell nanostructures have gained considerable attention due to their distinct enhanced fluorescence efficiency, multifunctionality, and specific applications. Recently, we developed a sequential growth process fabricate unique upconversion nanoparticles. Time evolution of morphology for the NaYF4:Yb/Er@NaGdF4 nanodumbbells has been extensively investigated. An Ostwald ripening mechanism proposed illustrate formation nanodumbbells. The hydrophilic exhibited strong showed...

10.1021/acsami.6b16842 article EN ACS Applied Materials & Interfaces 2017-02-28

The novel magnetic liposomal emodin nanocomposite (MLE) could serve as an efficient magnetically guided theranostic nanoagent against cancer.

10.1039/c8bm01530a article EN Biomaterials Science 2018-12-28

Phthalate plasticizers (PAEs) are posing a serious threat to human health, so it is urgent develop effective and reliable ways detect the food additives PAEs sensitively.

10.1039/c9an00251k article EN The Analyst 2019-01-01
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