- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Nanoparticle-Based Drug Delivery
- Effects and risks of endocrine disrupting chemicals
- Diet and metabolism studies
- RNA modifications and cancer
- Nanocluster Synthesis and Applications
- Nanoparticles: synthesis and applications
- Breast Lesions and Carcinomas
- Epigenetics and DNA Methylation
- Autophagy in Disease and Therapy
- Breast Cancer Treatment Studies
- Bone Tissue Engineering Materials
- Cancer-related gene regulation
- Quantum Dots Synthesis And Properties
- Wastewater Treatment and Nitrogen Removal
- Diet, Metabolism, and Disease
- Cancer and Skin Lesions
- Graphene and Nanomaterials Applications
- Perovskite Materials and Applications
- Pharmacological Effects of Natural Compounds
- Electrochemical sensors and biosensors
- Cytokine Signaling Pathways and Interactions
- Solid-state spectroscopy and crystallography
University of Science and Technology of China
2010-2025
Southwest University of Political Science & Law
2025
Anhui University of Traditional Chinese Medicine
2017-2023
Institute of Intelligent Machines
2023
Chinese Academy of Sciences
2023
Hefei Institutes of Physical Science
2023
Nanjing Traditional Chinese Medicine Hospital
2021
Anhui Provincial Hospital
2006-2020
State Grid Corporation of China (China)
2020
Hefei University of Technology
2019
Uniform and water-soluble Ag@reduced graphene oxide (Ag@rGO) nanocomposites can be prepared by a facile approach in the absence of additional reductants, which display much better antibacterial properties than that pure silver nanoparticles synthesized microwave irradiation, an equivalent effect comparison with general drug ampicillin. Their skin irritation tests use rat models are taken order to explore toxicity this nanocomposite, confirm no oedema or erythema appears on injured after...
Abstract The exploration of lead‐free halide perovskite nanocrystals (NCs) with intriguing optical properties is highly desirable owing to the toxicity and instability lead NCs. Here, a new kind uniform double Cs 2 NaBiCl 6 NCs are reported as versatile hosts accommodate ionic dopants for improving especially photoluminescence (PL). In contrast low deep‐blue PL quantum yield only 1.7% as‐synthesized pristine NCs, can be impressively regulated enhanced via doping Ag + , Mn 2+ or Eu 3+ ions in...
Abstract Commensal bacteria are crucial to maintain immune homeostasis in mucosal tissues and disturbances their ecology can affect disease susceptibility. Here, we report evidence that commensal shape the efficiency of surveillance tissues. Antibiotic-treated (Abt) mice were more susceptible development engrafted B16/F10 melanoma Lewis lung carcinoma, exhibiting a shortened mean survival time with numerous larger tumor foci lungs. The defective antitumor response Abt was independent...
Translating the unique characteristics of individual nanoscale components into macroscopic materials such as membranes or sheets still remains a challenge, engineering these structures often compromises their intrinsic properties. Here, we demonstrate that highly active carbonaceous nanofibers (CNFs), which are prepared through template-directed hydrothermal carbonization process, can be used versatile scaffold for constructing multifunctional membranes. In order to broad applicability CNF...
Abstract Lead halide perovskites have gained extensive attention in the photodetectors (PDs) field, but problems of intrinsic toxicity and poor stability still hamper their practical applications. Furthermore, ultraviolet (UV) PDs rarely been explored due to challenges, including lack suitable materials costly complicated fabrication processes. In order solve above problems, herein it is reported a novel all‐inorganic lead‐free CsAg 2 I 3 single crystal (SC) with pure phase high quality....
Abstract Herein, a kind of novel monocomponent hydrophilic and paramagnetic manganese(II) oxide nanocrystal is prepared in polar solution by one‐pot microwave‐assisted synthesis. This can be taken up efficiently to serve as an excellent T 1 magnetic resonance imaging (MRI) contrast agent with enhanced r value 0.81 mM −1 s . The key the success this method that no additional capping agents are required for coating onto surface via ligand exchange, facilitating research their intrinsic...
Diethylhexyl phthalate (DEHP) is suspected to be an inevitable factor related metabolic disease. Our previous study demonstrated that excess DEHP could exacerbate non-alcoholic fatty liver disease (NAFLD) in SD rats. Addressing the terra incognita DEHP-induced dysfunction, this used HepG2 cells investigate potential mechanisms involved toxicity vitro. The were established lipid overload model with oleic acid and BSA, then exposed different concentrations (5, 10, 25, 50, 100 μmol/l DEHP) of...
Currently, developing new types of simple and effective detection methods phthalate plasticizers (PAEs) remains challenging, whereas the process traditional instruments is tedious laborious. With regard to PAEs, their intrinsically poor Raman activity very low affinity onto metallic surfaces seriously obstruct realization directly surface-enhanced spectroscopy (SERS) detection. Here, a dual-mode sensing system with specific trace butyl benzyl (BBP, one PAEs) was demonstrated by constructing...
Purpose: Pachyman, derived from Poria cocos, has been used to treat gouty arthritis (GA) for thousands of years, although its precise role and mechanisms remain unclear. Herein, we investigate the therapeutic effects pachyman on GA explore their underlying mechanisms. Methods: Network pharmacology experimental methods were employed against GA. The protein-protein interaction network shared targets between gout was constructed. Furthermore, elucidated functions Subsequently, validated...
Point-wise suturing is the standard method for ensuring that patches effectively perform mechanically supportive functions in tissue repair. However, stress concentrations around suture holes can compromise mechanical stability of patches. In this study, we develop a suturable hydrogel patch with flaw-tolerance capabilities by leveraging multiscale deconcentration, inspired natural silk. This design mitigates concentration across two scales through synergistic integration nanoscale...
ZnO nanorods/Au nanocomposites with Au nanocrystals growing at tips of nanorods or located along the surface can be synthesized via a facile low-cost solution method. The number nanoparticles grown on controlled by tuning molar ratio to HAuCl4; thus, ZnO/Au heterostructures displayed tunable UV and visible emission intensity. cytotoxic studies two different cell lines (CHO cells Hela cells) indicated that hybrid are biologically nontoxic. MTT assays these consistent, showing nanomaterials...
Abstract Multicomponent Ni 7 Co 3 alloy–Au nanorings can be facilely synthesized at room temperature using metallic alloy as both reducing agent and sacrificial template in water. These novel hybrid are well biocompatible due to coating with poly(vinylpyrrolidone) gold nanoparticles. When increasing the molar ratio of salt from 1:1 5:1, number nanoparticles loaded on surface were found decreased, their morphology was transformed rod particle, remaining ring‐like assemblies. Their saturation...
Abstract Induction of autophagy is a common response cells upon exposure to nanomaterials and represents both safety concern an application niche for engineered nanomaterials. Herein, it reported that the magnetic property autophagy‐inducing activity Ni–Co alloy nanocrystal (NC) assemblies can be differentially “tuned” through altering material composition. A series NC assemblies, composed nanoparticles (NPs) with size about 30 nm, quickly synthesized under microwave irradiation in aqueous...
Melatonin is supposed to be an effective hepatoprotective agent. The effects and mechanisms of melatonin on alcoholic fatty liver (AFL) have not been well explored. aim this study was investigate the preventive therapeutic alcohol-induced rats. AFL rats were induced by intragastric infusion alcohol plus a high-fat diet for 6 weeks, (10, 20, 40 mg/kg) administered gastric perfusion. We also established acid overload cell model in HepG2 cells effect AMP-activated protein kinase (AMPK)...
Upconversional core-shell nanostructures have gained considerable attention due to their distinct enhanced fluorescence efficiency, multifunctionality, and specific applications. Recently, we developed a sequential growth process fabricate unique upconversion nanoparticles. Time evolution of morphology for the NaYF4:Yb/Er@NaGdF4 nanodumbbells has been extensively investigated. An Ostwald ripening mechanism proposed illustrate formation nanodumbbells. The hydrophilic exhibited strong showed...
The novel magnetic liposomal emodin nanocomposite (MLE) could serve as an efficient magnetically guided theranostic nanoagent against cancer.
Phthalate plasticizers (PAEs) are posing a serious threat to human health, so it is urgent develop effective and reliable ways detect the food additives PAEs sensitively.