A5004898930- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Oral and Maxillofacial Pathology
- Body Image and Dysmorphia Studies
- Allergic Rhinitis and Sensitization
- Hip and Femur Fractures
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Spinal Fractures and Fixation Techniques
- Trauma and Emergency Care Studies
- COVID-19 and healthcare impacts
- Spine and Intervertebral Disc Pathology
- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Bone Tumor Diagnosis and Treatments
- Congenital Ear and Nasal Anomalies
- Orthopedic Infections and Treatments
- Pelvic and Acetabular Injuries
- Total Knee Arthroplasty Outcomes
- Nasolacrimal Duct Obstruction Treatments
- Contact Dermatitis and Allergies
- Emergency and Acute Care Studies
- Digital Imaging in Medicine
- Scoliosis diagnosis and treatment
Imperial College Healthcare NHS Trust
2012-2024
Charing Cross Hospital
2013-2024
Guy's and St Thomas' NHS Foundation Trust
2024
Imperial College London
2009-2024
Kantonsspital Aarau
2024
Alexandria University
2020-2024
Royal Brompton Hospital
2009-2024
Royal Brompton & Harefield NHS Foundation Trust
2024
NYU Langone Health
2016-2023
New York University Langone Orthopedic Hospital
2016-2023
The full British Thoracic Society Guideline for Bronchiectasis in Adults is published
The effects of rhinosinusitis treatment upon asthma are disputed. first randomised prospective study surgical compared with medical therapy chronic in 90 patients and without nasal polyps was previously reported. Asthma symptoms, control, forced expiratory volume one second (FEV 1 ), peak flow, exhaled nitric oxide, medication use hospitalisation at 6 12 months from the start were also monitored. This paper reports these results 43 those concomitant asthma. Both associated subjective...
To review and report functional outcomes, complications, survivorship associated with total knee arthroplasty (TKA) in the treatment of post-traumatic arthritis (PTA).We conducted a systematic according to PRISMA guidelines. We searched PubMed, Cochrane Library, SCOPUS December 2015 for English-language clinical research studies, both prospective retrospective, examining use TKA PTA. All relevant articles were accessed full. The manual search included references retrieved articles. extracted...
Frailty in elderly trauma populations has been correlated with an increased risk of morbidity and mortality. The Score for Trauma Triage the Geriatric Middle-Aged (STTGMA) is a validated mortality score that evaluates 4 major physiologic criteria: age, comorbidities, vital signs, anatomic injuries. aim this study was to investigate whether addition additional frailty variables STTGMA tool would improve stratification middle-aged population.A total 1486 patients aged 55 years older who met...
The prevalence of malnutrition in patients undergoing lumbar spine surgery ranges from 5% to 50% and is associated with higher rates surgical site infections, medical complications, longer lengths stay, mortality.To determine if perioperative nutritional intervention decreases wound healing complications surgery.A prospective randomized controlled trial.Patients aged 55+ elective primary were included. Patients a preoperative albumin<3.5 g/dL defined as malnourished. Intervention group...
Objective To describe our experience of cerebrospinal fluid (CSF) rhinorrhea management. Design Retrospective. Setting Charing Cross Hospital, London, a tertiary referral center. Participants Fifty-four patients with CSF managed from 2003 to 2011. Main outcome measures Surgical technique; Recurrence. Results Etiologically, 36 were spontaneous and 18 traumatic. Eight two traumatic leaks had previous failed repairs in other units. Success rates after first second surgery 93% 100%,...
Body dysmorphic disorder (BDD) is defined as having a preoccupation with perceived flaw in one's appearance, which appears slight to others and significantly interferes person's functioning. When undetected septorhinoplasty patients, it will often lead poor outcomes.We performed prospective cohort study determine the prevalence of BDD our patients whether surgical correction could be considered.We recruited 34 being considered for tertiary referral rhinology clinic control group 50 from...
To determine whether a novel inpatient mortality risk assessment tool designed to be calculated in the emergency department setting can stratify patient-reported functional outcomes and at 1 year.Prospective cohort.Academic level trauma center.Six hundred eight-five patients >55 years of age who were orthopaedic surgery consults or between January 10, 2014, September 30, 2015.Calculation validated score for triage geriatric middle-aged (STTGMA) using each patient's demographics, injury...
Objectives: To investigate the efficacy of a novel geriatric trauma risk assessment tool [Score for Trauma Triage in Geriatric and Middle-Aged (STTGMA)] designed to predict inpatient mortality risk-stratify measures hospital quality cost care middle-aged orthopaedic patients. Design: Prospective cohort study. Setting: Academic medical center. Patients: One thousand five hundred ninety-two patients 55 years age older who were evaluated by surgery emergency department between October 1, 2014,...
Abstract Little data on UK prescribing patterns and treatment effectiveness for allergic rhinitis (AR) are available. We quantified unmet pharmacologic needs in AR by assessing based the behaviour of general practitioners (GP) during two consecutive pollen seasons (2009 2010). conducted a retrospective observational study with from Optimum Patient Care Research Database. assessed diagnoses prescription patients recorded diagnosis who took medication period. 25,069 2009 22,381 2010....
Chronic rhinosinusitis (CRS) is a chronic inflammatory disorder of the sinonasal cavities classified into two major phenotypes: CRS with nasal polyps (CRSwNP) and without (CRSsNP). The diagnosis based on clinical symptoms associated imaging and/or endoscopy findings mucosal inflammation.
Patterns of discharge location may be evident based on the “sickness” profile patient. This study sought to evaluate ability STTGMA tool, a validated mortality risk index for middle-aged and geriatric trauma patients, predict in cohort low-energy elderly hip fracture with successful planning measured by readmission rates. Low-energy patients aged 55 years older were prospectively followed throughout their hospitalization. On initial evaluation Emergency Department, each patient’s age,...
Cholesterol granulomas are the most common lesion of petrous apex. Traditionally, lesions apex have been accessible via open, infracochlear, and transtemporal approaches. We describe two cases in which endoscopic transsphenoidal approach was used to manage this lesion. The design study is as a review new setting tertiary referral unit London teaching hospital. Case 1: A 53-year-old man diagnosed with bilateral cholesterol apices. 2: 32-year-old woman right-sided granuloma main outcome...
Objective In this multicentric study involving three London hospitals, we compared ANCA‐positive and ANCA‐negative cocaine‐induced midline destructive lesions (CIMDL) patients to assess how presence of antineutrophil cytoplasmic antibodies (ANCA) may correlate with disease severity. Our secondary aims are better classify etiology centered around ANCA positivity and, consequently, management. Methods A retrospective review was performed identify CIMDL seen between January 2019 December 2022....
A new para-aminobenzoic-acid-containing natural product from the mango pathogenic organism Xanthomonas citri pv. mangiferaeindicae is described. By means of stable isotope precursor feeding combined with nontargeted LC-MS/MS, generated spectra were clustered and visualized in a molecular network. This led to identification member meroterpenoids, termed xanthomonic acid, which composed an isoprenylated para-aminobenzoic acid. In vitro cytotoxicity assays demonstrated activity acid against...
Sarcoidosis is an inflammatory, non‐caseating granulomatous multisystem disease associated with JAK‐STAT (Janus kinases‐signal transducer and activator of transcription proteins) pathway activation. We present a patient severe multi‐systemic sarcoidosis who showed marked improvement tofacitinib regards to pulmonary, cutaneous, nasal laryngeal disease. Tofacitinib prevented critical stenosis from progressing tracheostomy, induced regression cutaneous lesions improved pulmonary function in...