- Drug Transport and Resistance Mechanisms
- Tuberculosis Research and Epidemiology
- HIV/AIDS drug development and treatment
- Antibiotics Pharmacokinetics and Efficacy
- Machine Learning in Bioinformatics
- vaccines and immunoinformatics approaches
Bhopal Memorial Hospital & Research Centre
2025
Abstract Background We recently described the utility of ‘TB Concentration & Transport’ kit for bio-safe, ambient-temperature transport dried-sputum on Trans-Filter, and DNA Extraction’ extraction from Trans-Filter early diagnosis drug-resistant Tuberculosis (TB). This study aimed to assess feasibility compatibility these kits with Line Probe Assay (LPA) under National Elimination Programme (NTEP) settings. Methods Presumptive pulmonary TB/MDR-TB/XDR-TB patients (n=8491) who attended...
Early diagnosis and treatment is the key to successful outcome in patients with tuberculosis (TB). Xpert MTB/RIF assay has greatly reduced lag time for of TB patients. However, despite high sensitivity specificity assay, test failure can occur due various reasons. We aim identify reasons errors, indeterminate, invalids no results that may be useful initiating corrective measures assay. A total 1052 smear negative samples, including pulmonary(69.9%) extra-pulmonary(53.3%) samples were tested...