A5014862398- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Cancer Genomics and Diagnostics
- Lymphoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Viral-associated cancers and disorders
- Oral and Maxillofacial Pathology
- Musculoskeletal synovial abnormalities and treatments
- Tumors and Oncological Cases
- Renal and related cancers
- Hedgehog Signaling Pathway Studies
- Renal cell carcinoma treatment
- Ovarian cancer diagnosis and treatment
- Pluripotent Stem Cells Research
- Cancer and Skin Lesions
- Genomic variations and chromosomal abnormalities
- Cancer-related molecular mechanisms research
- Neurofibromatosis and Schwannoma Cases
- Vascular Tumors and Angiosarcomas
- Colorectal and Anal Carcinomas
- Chronic Lymphocytic Leukemia Research
- Cardiac tumors and thrombi
- BRCA gene mutations in cancer
- Cervical Cancer and HPV Research
- CRISPR and Genetic Engineering
University of Nebraska Medical Center
2007-2022
Nebraska Medical Center
2002-2020
Chelsea and Westminster Hospital NHS Foundation Trust
2016
University of Nebraska–Lincoln
2010
CHI Health Creighton University Medical Center - Bergan Mercy
2009
Inje University Sanggye Paik Hospital
2009
Houston Methodist
2009
Methodist Hospital
2009
Cornell University
2009
Research Medical Center
2001
The cytogenetic findings for two epithelioid hemangioendotheliomas are reported. An identical chromosomal translocation involving chromosomes 1 and 3 [t(1;3)(p36.3;q25)] was detected in both cases of hemangioendothelioma, possibly representing a characteristic rearrangement this histopathologic entity. presence clonal karyotypic abnormalities supports neoplastic origin the variant hemangioendothelioma. Identification 1;3 may be useful diagnostically. Should additional studies confirm these...
Cytogenetic correlations among most types of peripheral T-cell lymphoma (PTCL) have not been very informative to date. This study aimed identify recurrent chromosomal abnormalities in angioimmunoblastic (AITL), ALK-negative anaplastic large cell (ALK-ALCL) and lymphoma, unspecified (PTCL-US), evaluate their prognostic value. We reviewed the cytogenetic findings 90 previously-diagnosed cases PTCL correlated with specific histological subtype. The common for AITL were 5q (55%), 21 (41%) 3q...
Abstract Chondroid lipoma, a rare benign adipose tissue tumor, may histologically resemble myxoid liposarcoma or extraskeletal chondrosarcoma, but is genetically distinct. In this study, an identical reciprocal translocation, t(11;16)(q13;p13), was identified in three chondroid lipomas, finding consistent with previously isolated reports. A fluorescence situ hybridization (FISH)‐based positional cloning strategy using series of bacterial artificial chromosome (BAC) probe combinations...
Mixed neuronal-glial tumors are rare and challenging to subclassify. One recently recognized variant, papillary glioneuronal tumor (PGNT), is characterized by prominent pseudopapillary structures elements. We identified a novel translocation, t(9;17)(q31;q24), as the sole karyotypic anomaly in two PGNTs. A fluorescence situ hybridization (FISH)-based positional cloning strategy revealed SLC44A1, member of choline transporter-like protein family, PRKCA, kinase C family...
Summary Burkitt lymphoma (BL), an aggressive B‐cell malignancy, is often curable with short intensive treatment regiments. Nearly all BLs contain rearrangements of the MYC /8q24 region; however, recent cytogenetic studies suggest that certain secondary chromosomal aberrations in BL correlate adverse prognosis. In this multi‐centre study, frequency and impact on clinical outcome del(13q) +7 addition to as detected by fluorescence situ hybridization (FISH) children adolescents intermediate...