A5005918843- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Polyamine Metabolism and Applications
- Lung Cancer Research Studies
- Amino Acid Enzymes and Metabolism
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple and Secondary Primary Cancers
- Cancer, Lipids, and Metabolism
- Neuroendocrine Tumor Research Advances
- Metabolism, Diabetes, and Cancer
- Inflammatory mediators and NSAID effects
- Cancer Research and Treatments
- Estrogen and related hormone effects
- Cancer Risks and Factors
- Pancreatitis Pathology and Treatment
- Epigenetics and DNA Methylation
University of California, Irvine
2014-2025
University of California, Irvine Medical Center
2009-2024
UC Irvine Health
2015-2024
Barry University
2020
Palmetto Hematology Oncology
2019
Irvine Valley College
2019
Orange (Poland)
2015
National Cancer Institute
2006-2011
Cornell University
2011
Cancer Prevention Institute of California
2010
Abstract BACKGROUND. Platinum‐based adjuvant chemotherapy in randomized trials has failed to provide a survival benefit patients with resected stage I nonsmall cell lung cancer (NSCLC). Using data from the California Cancer Registry (CCR), we explored factors that had detrimental effects on NSCLC identify subset of at high risk for disease recurrence and subsequent mortality. METHODS. Between 1989 2003, 19,702 incident cases CCR were identified subgrouped into IA IB disease. Patient...
Abstract Background: Poor survival among colorectal cancer (CRC) cases has been associated with African-American race and low socioeconomic status (SES). However, it is not known whether the observed poor of CRC due to SES itself and/or treatment disparities. We set out determine this using data from large, population-based California Cancer Registry database. Methods: A case-only analysis was conducted including all age groups 1994 2003, descriptive relevant clinical variables, race, SES....
Purpose Although uncommon, melanoma is associated with poor survival characteristics among African Americans and Hispanics compared non-Hispanic whites (NHWs). Low socioeconomic status (SES) also patients melanoma, but it not known whether this because of SES itself or treatment disparities. We set out to determine by using the large, population-based California Cancer Registry (CCR) database as a model. Patients Methods conducted case-only analysis CCR data (1993 2003), including...
Ewing sarcoma is a high-grade malignancy that most often occurs in children. Because its occurrence adults has been historically low, few studies have published on the epidemiology of this group patients. By using data from large, population-based cancer registry, authors designed present study to examine outcome children and adult patients with relevant prognostic factors.A retrospective analysis patient cases California Cancer Registry database was performed identify incident diagnosed...
Abstract Background: Poor survival in pancreatic adenocarcinoma is associated with African-American race and also low socioeconomic status (SES). However, it not known whether the observed poor of cases due to SES itself and/or treatment disparities. We set out determine this using large, population-based California Cancer Registry (CCR) database as a model. Methods: conducted case-only analysis CCR data (1989-2003), including descriptive relevant clinical variables SES. The variable used...
Purpose Classification changes for bronchioloalveolar carcinoma (BAC) by the WHO in May 1999 narrowed its definition. This study was undertaken an attempt to characterize impact of these on epidemiology BAC. Patients and Methods retrospective involves data analysis from population-based Cancer Surveillance Programs three Southern California counties 1995 2003. BAC cases diagnosed after are compared with before that time clinicopathologic variables including survival. Results Incident...
PURPOSE: Proximal colon cancers are more likely to present with advanced stage than distal cancers; however, previous reports conflict regarding the independent prognostic significance of tumor location on survival. We examined survival by cancer subsite use data from California Cancer Registry. METHODS: An analysis cases 1994 2004 was conducted, follow-up through 2006. Colon defined as proximal (cecum, ascending colon, hepatic flexure), transverse descending (splenic flexure, colon), and...
Inflammatory breast cancer (IBC) is an aggressive form of associated with overexpression Her2/Neu (human epidermal growth factor-like receptor 2 (HER2)) and poor survival. We investigated survival differences for IBC patient cases based on hormone status HER2 using data from the California Cancer Registry, as contrasted locally advanced (LABC), metastatic (MBC) non-T4 cancer. A case-only analysis 80,099 incident female in Registry during 1999 to 2003 was performed, follow-up through March...
Racial minorities exhibit poor survival with nonsmall cell lung cancer (NSCLC) that generally is attributed to low socioeconomic status (SES). In this study, the authors investigated role of SES in disparity among patients stage I NSCLC.A case-only analysis was performed on California Cancer Registry (CCR) data (1989-2003). Univariate analyses were using Kaplan-Meier method. Multivariate Cox proportional hazards ratios.In total, 19,702 incident cases NSCLC analyzed. Low identified more...
Purpose: Colorectal cancer (CRC) incidence has decreased over the past three decades, due largely to screening efforts. Relatively little is known about CRC among young adult (YA) population ages 20–39, as typically commences at age 50 for average-risk individuals. We examined with a focus on YAs in order identify high-risk subgroups. Methods: analyzed 231,544 incident cases from 1988–2009 (including 5617 20–39 years of age) California Cancer Registry. assessed age-specific rates by...
Quantification of miRNAs in blood can be potentially used for early disease detection, surveillance monitoring and drug response evaluation. However, quantitative robust measurement is still a major challenge large part due to their low concentration complicated sample preparation processes typically required conventional assays. Here, we present the 'Integrated Comprehensive Droplet Digital Detection' (IC 3D) system where plasma containing target encapsulated into microdroplets,...
Pancreatic adenosquamous carcinoma has historically been characterized as having a more aggressive clinical course than ductal adenocarcinoma. The natural history of this disease, however, is essentially unknown. We evaluated the characteristics all patients with pancreatic recorded in California Cancer Registry 2000–2007 and compared them to those Ninety-five 14,746 adenocarcinoma were identified. Demographics similar between subtypes (p > 0.05). Disease stage at presentation was also...
Information about adenosquamous carcinoma of the colon and rectum is scarce because its extremely low incidence.The aim this study was to examine prognostic significance a histological diagnosis in comparison with adenocarcinoma rectum.This retrospective design.California Cancer Registry data from 1994 through 2004 follow-up 2008 were analyzed.Patients included whose cancer rectum, excluding anus tumor histology carcinoma, surgically treated.The primary outcomes measured histology-specific...
The polyamine-inhibitory regimen difluoromethylornithine (DFMO)+sulindac has marked efficacy in preventing metachronous colorectal adenomas. Polyamines are synthesised endogenously and obtained from dietary sources. Here we investigate polyamine intake outcomes the DFMO+sulindac adenoma prevention trial. Dietary data were available for 188 of 267 patients completing study. Total content was derived by sum putrescine, spermine spermidine values categorised into two groups: highest (>75–100%)...