David Kwon
A5015987197- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Cancer Research and Treatments
- Renal cell carcinoma treatment
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Chemokine receptors and signaling
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Cardiac Arrhythmias and Treatments
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- History of Medical Practice
- Ultrasound in Clinical Applications
- Thyroid and Parathyroid Surgery
- Sympathectomy and Hyperhidrosis Treatments
- Cardiac Arrest and Resuscitation
- CAR-T cell therapy research
- Cancer Cells and Metastasis
Henry Ford Hospital
2015-2025
Henry Ford Health System
2007-2024
Chicago Department of Public Health
2024
University of Miami
2020
Cancer Treatment Centers of America
2015
Wayne State University
2005-2015
National Institutes of Health
2014
FX Palo Alto Laboratory
2014
CardioDx (United States)
2014
Jacksonville College
2014
Ablative therapies have been increasingly utilized in the treatment of locally advanced pancreatic cancer (LAPC). Irreversible electroporation (IRE) is an energy delivery system, effective ablating tumors by inducing irreversible membrane destruction cells. We aimed to demonstrate efficacy with IRE as part multimodal LAPC.From July 2010 October 2014, patients radiographic stage III LAPC were treated and monitored under a multicenter, prospective institutional review board-approved registry....
ABSTRACT Bone marrow‐derived mesenchymal stromal cells (BMSCs) are multipotential stem capable of differentiation into numerous cell types, including fibroblasts, cartilage, bone, muscle, and brain cells. BMSCs also secrete a large number growth factors cytokines that critical to the repair injured tissues. Because extraordinary plasticity ability syngeneic or allogeneic tissue‐repair factors, we investigated therapeutic efficacy for healing fascial cutaneous incisional wounds in...
Abstract Bone marrow stem cells participate in tissue repair processes and may have a role wound healing. Diabetes is characterised by delayed poor We investigated the potential of bone marrow‐derived mesenchymal stromal (BMSCs) to promote healing fascial wounds diabetic rats. After manifestation streptozotocin (STZ)‐induced state for 5 weeks male adult Sprague–Dawley rats, was severely compromised. Compromised rats excessive polymorphonuclear cell infiltration, lack granulation formation,...
The safety of oncolytic adenovirus-mediated suicide and interleukin-12 (IL12) gene therapy was evaluated in metastatic pancreatic cancer patients. In this phase I study, a replication-competent adenovirus (Ad5-yCD/mutTKSR39rep-hIL-12) expressing yCD/mutTKSR39 (yeast cytidine deaminase/mutant S39R HSV-1 thymidine kinase) human IL-12 injected into tumors 12 subjects with (T2N0M1-T4N1M1) at escalating doses (1 × 1011, 3 or 1 1012 viral particles). Subjects received 5-fluorocytosine (5-FC) for 7...
Abstract Purpose: Pancreatic ductal adenocarcinoma (PDAC) patients with tumors enriched for the basal-like molecular subtype exhibit enhanced resistance to standard-of-care treatments and have significantly worse overall survival compared classic subtype–enriched tumors. It is important develop genomic resources, enabling identification of novel putative targets in a statistically rigorous manner. Experimental Design: We compiled single-cell RNA sequencing (scRNA-seq) atlas human pancreas...
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