A5067377418- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tracheal and airway disorders
Perth Children's Hospital
2022-2024
The Kids Research Institute Australia
2022-2024
Princess Margaret Hospital for Children
2022-2024
Abstract Introduction The European Respiratory Society Oscillometry Taskforce identified that clinical correlates of bronchodilator responses are needed to advance oscillometry in practice. understanding bronchodilator‐induced changes preterm lung disease is poor. Here we describe a comparison assessments performed using and spirometry population born very explore the relationship between respiratory function outcomes. Methods Participants aged 6–23 ≤32 ( N = 288; 132 with bronchopulmonary...
Survivors of very preterm birth (<32 weeks gestation) experience lung health deficits that may be progressive over time [1]. Respiratory symptoms are frequently diagnosed as asthma in this population with studies reporting children born (<37 up to 5 times more at risk developing wheezing disorders than their term-born counterparts [2], and 50% by mid-childhood [3]. Contrary the childhood paradigm, patient is typically non-atopic [4] low fractional exhaled nitric oxide (FeNO) [5]....
Background: Despite the significant burden of lung disease in children surviving very preterm birth, there are currently no evidence-based interventions to improve their health. We tested hypothesis that inhaled corticosteroids (ICS) function this population. Further, we aimed determine predictors a positive response ICS therapy.Methods: undertook randomised, double-blind, placebo-controlled trial whether ICS, fluticasone propionate, improves childhood survivors birth (6 12 years). randomly...
Introduction: The European Respiratory Society Oscillometry Taskforce identified that clinical correlates of bronchodilator responses are needed to advance oscillometry in practice. understanding bronchodilator-induced changes preterm lung disease is poor. Here we describe a comparison assessments performed using and spirometry population born very explore the relationship between respiratory function outcomes. Methods: Participants aged 6-23 ≤32 (N=288; 132 with bronchopulmonary dysplasia)...
<b>Introduction:</b> Spirometry identifies a bronchodilator response (BDR) in >30% of children born preterm; however developmental delays may inhibit the use this test. We assessed feasibility and sensitivity spirometry oscillometry to assess BDR young-adults very preterm (≤32 weeks gestation). <b>Methods:</b> Preterm (N=131; 10.3±2.3 years), (N=127; 19.3±1.4 yrs) term-born controls (N=64) had (400mcg salbutamol via spacer) by oscillometry. Significance thresholds were: (≥Δ12% (+Δ200ml...