Alex Williamson

ORCID: 0000-0003-2724-1704
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About
Contact & Profiles
Research Areas
  • Autopsy Techniques and Outcomes
  • Healthcare cost, quality, practices
  • COVID-19 and healthcare impacts
  • Health Sciences Research and Education
  • Gestational Trophoblastic Disease Studies
  • Health and Medical Research Impacts
  • COVID-19 Clinical Research Studies
  • Congenital Diaphragmatic Hernia Studies
  • Congenital Anomalies and Fetal Surgery
  • Renal and related cancers
  • Global Cancer Incidence and Screening
  • Genital Health and Disease
  • Working Capital and Financial Performance
  • Trauma and Emergency Care Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • SARS-CoV-2 and COVID-19 Research
  • Medical Research and Practices
  • Library Collection Development and Digital Resources
  • Adenosine and Purinergic Signaling
  • Child and Adolescent Health
  • Neuroblastoma Research and Treatments
  • Injury Epidemiology and Prevention
  • Sarcoma Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Urological Disorders and Treatments

Office of Chief Medical Examiner
2025

Northwell Health
2014-2024

Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2018-2023

Mayo Clinic
2023

WinnMed
2023

Hofstra University
2012-2022

University of Sheffield
2021

Hemel Hempstead Hospital
2021

Long Island Jewish Medical Center
2012-2019

IJ Research (United States)
2019

Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection caused by the JC virus that has no proven effective treatment. Although rare cases of PML have occurred with other anti-CD20 therapies, there had been prior associated ocrelizumab.To report first ever case occurring ocrelizumab monotherapy in a patient progressive multiple sclerosis without immunomodulation.This was reported from academic medical center. The while receiving monotherapy.Ocrelizumab monotherapy.A...

10.1001/jamaneurol.2021.0627 article EN JAMA Neurology 2021-03-16

This study represents the largest compilation to date of clinical and postmortem data from decedents with coronavirus disease 2019 (COVID-19). It will augment previously published small series autopsy case reports, refine clinicopathologic considerations, improve accuracy future vital statistical reporting.To accurately reflect preexisting diseases pathologic conditions SARS-CoV-2 (severe acute respiratory syndrome 2) infection through autopsy.Comprehensive 135 evaluations COVID-19-positive...

10.5858/arpa.2020-0786-sa article EN Archives of Pathology & Laboratory Medicine 2021-01-15

The impact of COVID-19 on heart transplant (HTx) recipients remains unclear, particularly in the early post-transplant period.We share novel insights from our experience five HTx patients with (three within 2 months post-transplant) institution at epicenter pandemic.All exhibited moderate (requiring hospitalization, n = 3) or severe ICU and/or mechanical ventilation, 2) illness. Both cases illness were transplanted approximately 6 weeks before presentation and acquired through community...

10.1111/tid.13382 article EN Transplant Infectious Disease 2020-06-25

Team-based learning (TBL) has been integrated into undergraduate and medical education curricula in many institutions. However, TBL not widely introduced postgraduate education. Our study aimed to measure the effect of on promoting teamwork setting pathology residency training.Four sessions were held individual group readiness assurance tests (IRAT/GRATs) performed; scores compared using Wilcoxon matched-pairs signed rank tests. Residents completed 18-item validated team performance surveys...

10.1309/ajcpb8t1dzkcmwut article EN American Journal of Clinical Pathology 2014-06-12

Osteosarcoma (OS) is the most common type of primary bone cancer affecting children and adolescents. OS has a high propensity to spread meaning disease often incurable fatal. There have been no improvements in survival rates for decades. This highlights an urgent need development novel therapeutic strategies. Here, we report vitro vivo data that demonstrates role purinergic signalling, specifically, B isoform receptor P2RX7 (P2RX7B), progression metastasis.TE85 MNNG-HOS cells were...

10.1016/j.jbo.2021.100398 article EN cc-by-nc-nd Journal of bone oncology 2021-10-22

To the Editor.—We wish to advance discussion regarding potential transmission of coronavirus disease 2019 (COVID-19) infection from decedents autopsy and/or morgue personnel.1In March 2020 one us (A.K.W.) started an email distribution list among nearly 200 participants, most whom are pathologists, for discussing issues relating decedent management and amid COVID-19 pandemic. A recent survey listserv participants asked how many autopsies had been performed on individuals known be positive,...

10.5858/arpa.2020-0345-le article EN Archives of Pathology & Laboratory Medicine 2020-06-10

ABSTRACT The author summarizes the benefits and disadvantages of peer review discusses a number examples difficulties with it that have arisen in medical literature. In absence generally accepted alternative, she sets out conditions under which present system should be operated so as to achieve its purpose.

10.1087/095315103320995041 article EN Learned Publishing 2003-01-01

Clostridium sordellii (C. sordellii) is an anaerobic gram-positive rod most commonly found in the soil and sewage but also as part of normal flora gastrointestinal tract vagina a small percentage healthy individuals. C. infection considered to result from childbirth, abortion, and/or gynecological procedures. Although many strains are nonpathogenic, virulent toxin-producing exist. Infection with this organism typically manifests patient experiencing septic shock rapidly followed by end-organ...

10.1093/labmed/lmw025 article EN Laboratory Medicine 2016-07-01

<h3>Importance</h3> The true incidence of sudden unexplained death in childhood (SUDC), already the fifth leading category among toddlers by current US Centers for Disease Control and Prevention estimates, is potentially veiled varied certification processes medicolegal investigative offices across United States. <h3>Objective</h3> To evaluate frequency SUDC incidence, understand its epidemiology, assess consistency medical examiner coroner investigation system. <h3>Design, Setting,...

10.1001/jamanetworkopen.2020.23262 article EN cc-by-nc-nd JAMA Network Open 2020-10-30

A 2 year 9 month-old girl presented with active hemorrhage from a Wilms' tumor. The was controlled embolization of the left renal artery and nephrectomy subsequently performed. Embolization to control bleeding in trauma scenarios as preoperative intervention minimize blood loss has been extensively reported pediatric population. There are very few case reports an actively

10.1016/j.epsc.2014.05.013 article EN cc-by-nc-nd Journal of Pediatric Surgery Case Reports 2014-06-01

Mucocele of the appendix is a rare entity in pediatrics, with few case reports literature. We present 17-year-old male right lower quadrant pain who was found to have an appendiceal mucocele while being evaluated for appendicitis. Laparoscopic-assisted resection performed, pathology confirming low-grade mucinous neoplasm appendix, tumor scarcely described pediatric population. He underwent complete negative margins, rendering him cured without need any further or treatment. review literature...

10.1016/j.epsc.2016.11.014 article EN cc-by-nc-nd Journal of Pediatric Surgery Case Reports 2016-11-27

10.1087/095315101300059594 article EN Learned Publishing 2001-04-01

Key Teaching Points•An undifferentiated mass on a device lead can result in delayed or unnecessary treatments.•We describe novel technique involving transesophageal echocardiogram–guided biopsy of lead-associated by means bioptome.•This safe did not affect the stability integrity and was crucial for determining etiology facilitating appropriate care our patients. •An

10.1016/j.hrcr.2019.03.001 article EN cc-by-nc-nd HeartRhythm Case Reports 2019-03-15

respiratory distress syndrome management can include corticosteroids, as they may decrease the time on a ventilator and reduce mortality. 9Corticosteroids are also administered if there is suspicion of adrenal insufficiency or indicated because an underlying condition.Currently, World Health Organization major critical care infectious diseases associations advise against routine corticosteroid use in COVID-19 patients, mainly out concern for slowing viral clearance.][11][12] It interesting...

10.5858/arpa.2020-0300-le article EN Archives of Pathology & Laboratory Medicine 2020-05-18

A 45-year-old man from El Salvador with no past medical history presented cough and chest pain. Investigations revealed 60% peripheral eosinophilia (absolute count 12.3 K/uL). Cardiac imaging was consistent myocarditis intracardiac thrombus formation. Endomyocardial biopsy confirmed eosinophilic infiltration of the myocardium, bone marrow showed hypercellular 28% eosinophils. Cytogenetics/fluorescence in situ hybridization (FISH) positive FIP1L1-PDGFRA rearrangement. The patient treated for...

10.7759/cureus.43138 article EN Cureus 2023-08-08

Localized cystic disease of the kidney (LCDK) is a rare condition found primarily in adults, with total number documented cases less than 75. Its incidence pediatric population even more minuscule. It benign condition, but can be difficult to classify certainty on imaging, often necessitating surgical excision adequately rule out malignancy. We present case six-year-old child mass who underwent radical nephroureterectomy, for which pathology showed LCDK. then review literature subject.

10.1016/j.epsc.2016.06.016 article EN cc-by-nc-nd Journal of Pediatric Surgery Case Reports 2016-07-06
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