We have studied spiral ganglion cell (SGC) survival and soma size in neonatally pharmacologically deafened kittens. They were implanted with a four-electrode array the left cochlea at 100 to 180 or more days of age. Eight animals chronically stimulated approximately 1000 hours over 60 charge-balanced, biphasic current pulses; three unstimulated controls. Using three-dimensional computer-aided reconstruction cochlea, SGC position cross-sectional area stored. was mapped organ Corti by...

Background and purpose — Integration of repaired cartilage with surrounding native is a major challenge for successful tissue-engineering strategies repair. We investigated whether incorporation mesenchymal stem cells (MSCs) into the collagen scaffold improves integration repair defects in cynomolgus macaque model. Methods Cynomolgus bone marrow-derived MSCs were isolated incorporated type-I gel. Full-thickness osteochondral (3 mm diameter, 5 depth) created patellar groove 36 knees 18...

Abstract Articular cartilage has a poor healing capacity, and regeneration is not always warranted to achieve healing. On the other hand, collagen scaffolds have been shown support of articular defects in animal models, whereas bone morphogenetic protein‐2 (BMP‐2) known cause chondrogenic differentiation marrow‐derived mesenchymal stem cells (MSCs). The purpose this study was evaluate effectiveness intra‐articular administration BMP‐2 into marrow–derived MSCs recruited using original...

Containment using a soil-bentonite mixture (SBM) cut-off wall is valid method to prevent the contaminants in soil from migrating aquifer. A new construction technique for SBM vertical has been developed by employing trench cutting and re-mixing deep achieve excellent homogeneity of wall. This paper addresses this laboratory testing results on hydraulic barrier performance focusing its chemical compatibility. Hydraulic conductivity values were measured specimens, which processed various types...

The horizontal and vertical components of the fluid force pressure acting on a girder bridge due to tsunami like solitary wave are measured in hydraulic experiment their characteristics discussed. peak impact is estimated basis change added mass structure. seaward side also estimated. critical for stability as strength bolts used shoes against shear stress.

Prolonged dislocation of the patella is a rare condition and often related to severe osteoarthritis (OA) femorotibial (FT) joint. For this condition's treatment, numerous surgical techniques using total knee arthroplasty (TKA) have been published. To best our knowledge, case report first description use lateral release alone treat recurrent patellar subluxation with TKA. An interesting point in that patient had good recovery after TKA spite quite long-term (a duration almost 55 years) her...

ABSTRACTThis study aimed to investigate the possibility of modeling wave height and set-up by using representative method caused air bubbles in irregular waves surf zone. Two regular wave-breaking models with bubble effects were directly employed modified obtain new models. These can be used compute root mean square (RMS) based on conservation laws energy flux momentum. Model I was solved analytically for a beach plane slope numerically an spilling plunging breakers, separately....

The horizontal and vertical components of tsunami force acting on a model bridge beam are measured in two-dimensional experiments. wave pressure the is also at offshore, upper lower sides beam. A plate used as order to investigate basic characteristics it. authors show pressure, comparing with relatively complicated cross section. In comparison, mention role reducing by air under

Based on the field surveys in 2011 Off Pacific Coast of Tohoku Earthquake, resistant function earth banks and reducing dug pools against Tsunami flood have been indicated by authors. In this paper, above functions discussed applying both experimental studies analytical simulations. As results study, erosion resistance banks, characteristics such as depth flow velocity at back side to reduce active force can be discussed. Furthermore, technical possibilities apply artificial canals proposed...

Reports of congenital abnormalities the lateral meniscus include discoid meniscus, accessory double-layered and ring-shaped meniscus. Particularly, only a few cases have been reported. We report case in which an additional semicircular was observed under normal The hemimeniscus resected by means arthroscopic surgery. This demonstrates interesting extremely rare anatomical abnormality

Using an animal model, we have studied the response of auditory brain stem to cochlear implantation and effect intracochlear factors on this response. Neonatally, pharmacologically deafened cats (100 more than 180 days old) were implanted with a 4‐electrode array in both cochleas. Then, left cochlea each cat was electrically stimulated for total periods up 1000 hours. After terminal 14 C‐2‐deoxyglucose (2DG) experiment, fraction right inferior colliculus significant accumulation 2DG label...

We have used the carbon dioxide (CO(2)) laser and gallium aluminium arsenide (GaAlAs) diode with flexible fiber delivery instruments for vaporization of inferior nasal turbinate in pediatric patients since 1993. Under endoscopic control, whole was vaporized by 5-10 W output delivered via an optical fiber. Generally, mucosa changes into normal mucosa, symptoms improve. The greatest symptomatic improvement obstruction. results obtained two devices were similar although they had different...

This study investigates a wall and trench combination to identify its benefits as defense measure against an overtopping tsunami-like wave. The focuses on several arrangements geometries of combined structural system, located the shoreline. system is assessed via numerical model, which initially calibrated by physical experiments wave transformations. A dam break event used model interaction with structures. Resulted properties are investigated behavior from viewpoint structure geometry...

Pressure acting on a bridge superstructure with π-shaped and rectangular cross-sections are measured. The characteristics of the pressure underside deck investigated. caused by air compression is also discussed. author shows that at landward corner inside cross-section was compression. seaward point model smaller than under just breaking non-breaking wave conditions.

The applicability of the existing prediction methods wave force acting on a horizontal plate above still water level is investigated by comparing estimated with measured force. numerical model as well equations from experimental results investigated. Some overestimate force, and some underestimate