A5012614805- Digestive system and related health
- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Infant Health and Development
- Probiotics and Fermented Foods
- Pancreatitis Pathology and Treatment
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- Human Health and Disease
- Gastroesophageal reflux and treatments
- Diet, Metabolism, and Disease
- Inflammatory Bowel Disease
- Gut microbiota and health
- Infant Nutrition and Health
- Celiac Disease Research and Management
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Neurological Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- IgG4-Related and Inflammatory Diseases
- Microscopic Colitis
- Esophageal and GI Pathology
- Acute Myocardial Infarction Research
- Abdominal Surgery and Complications
- Erythrocyte Function and Pathophysiology
Saint Petersburg State Pediatric Medical University
2015-2025
Ministry of Health of the Russian Federation
2019-2020
Vitebsk State Medical University
2017
First Pavlov State Medical University of St. Petersburg
2017
Eosinophilic esophagitis (EoE) is characterized by endoscopic signs and detection of more than 15 eosinophils per high-power field view in biopsies the esophageal mucosa. Due to deep chronic eosinophilic inflammation, it can cause complications: stenosis, rarely perforation. Intramural dissection (IED) a previously undescribed complication EoE children. We present case IED 15-year-old boy, which clinically manifested itself as sudden epigastric pain radiating back nausea against background...
1Moscow Clinical Research and Practical Center, Moscow Healthcare Department, Moscow; 2A.I. Evdokimov State University of Medicine Dentistry, Ministry Health Russia, 3Kazan Medical University, Kazan; 4Kazan (Volga) Federal 5Far Eastern Khabarovsk; 6Morozov City Children’s Hospital, 7I.I. Mechnikov North-Western Saint Petersburg; 8Siberian Tomsk; 9M.F. Vladimirsky Regional Institute, 10Maimonides Classical Academy, 11V.I. Razumovsky Saratov Saratov; 12I.M. Sechenov First 13S.M. Kirov Military...
1Moscow Clinical Research-and-Practical Center, Moscow Healthcare Department, Moscow; 2A.I. Evdokimov State University of Medicine and Dentistry, Ministry Health Russia, 3Children’s Research 4I.I. Mechnikov North-Western Medical University, Saint Petersburg; 5M.F. Vladimirsky Regional Institute, 6Russian Academy Postgraduate Education, 7Novosibirsk Novosibirsk; 8Russian Children’s Hospital, 9Department Pediatrics, Russian 10I.P. Pavlov First Petersburg 11Acad. Yu.E. Veltishchev Institute...
The final version of the draft protocol for diagnosis and treatment Crohn’s disease in children, developed by experts Russian Society Pediatric Gastroenterology, Hepatology Nutrition, is presented article. This project has been repeatedly discussed pediatric gastroenterologists - specialists study IBD children during round tables at XXV-th XXVI-th Congres Gastroenterologists Russia and, after approval, will be form clinical recommendations.
A group of leading experts in the field pediatric gastroenterology prepared clinical recommendations for diagnosis and treatment functional digestive disorders (FDD) children; they have summarized international domestic experience suggested tactics a pediatrician everyday practice. The first part discusses modern views on disorders, their development mechanisms terminology. article considers biopsychosocial model as well an updated classification based Rome criteria IV, including experience....
Inflammatory bowel disease (Crohn's and ulcerative colitis) has a tendency to manifest at earlier age. In childhood (< 6 years of age) it an especially severe course is characterized by high grade inflammation, predominantly in the colon, complication extra-intestinal autoimmune injury. At younger age, Crohn's colitis require more aggressive treatment with frequently poor results. From genetic point view, monogenic mutations controlling immune response are characteristic for these...
A group of experts, leading specialists in the field pediatric gastroenterology have prepared clinical recommendations for diagnosis and treatment functional digestive disorders children; they summarized international domestic experience, suggesting tactics everyday pediatrician's practice. The second part guidelines discusses with abdominal pain: nausea vomiting, dyspepsia, irritable bowel syndrome, pain. authors clarified definitions, classification criteria dyspepsia syndrome taking into...
Pancreatology Club Professional Medical Community, 1A.S. Loginov Moscow Clinical Research and Practical Center, Healthcare Department, Moscow; 2A.I. Evdokimov State University of Medicine Dentistry, Ministry Health Russia, 3Kazan University, Kazan; 4Kazan (Volga) Federal 5Far Eastern Khabarovsk; 6Morozov City Children’s Hospital, 7I.I. Mechnikov North-Western Saint Petersburg; 8Siberian Tomsk; 9M.F. Vladimirsky Regional Institute, 10Maimonides Classical Academy, 11V.I. Razumovsky Saratov;...
The article provides an analysis of changes in ideas about pathogenetic mechanisms, approaches to the diagnosis and treatment irritable bowel syndrome children. Current data on pathophysiological mechanisms IBS are presented. Algorithms for management children with this pathology presented, based new positions Rome IV criteria Russian recommendations functional disorders digestive system
Introduction . The intestinal microbiome is an integral part of the health its owner and performs several important functions: metabolic, coordinating, protective, epigenetic, which are closely interactive. In conditions dysbiosis, disturbances these functions contributes to different disorders.The immune system interacts with microbiota. It represented by all cells: T- B-lymphocytes, T-regulatory, dendritic cells, macrophages. Micropresentation antigens occurs through M-cells located...
.
In recent years the non-alcoholic fatty liver disease (NAFLD) has become one of most common in children and adolescents. This phenomenon is explained by sharp rise obesity among population worldwide, including children, increased co-morbidities associated with obesity. There sufficient evidence that age gender are important determinants risk for development children. reason to believe an role pathogenesis NAFLD may play a hormonal profile adolescents, family history, state insulin...
The paper gives an update on the problem of studying gut microbiota and a classification representatives intestinal microflora describes its positive negative functions. authors depict indications for use drugs, such as probiotics, to treat different childhood diseases from clinical standpoint evidence-based medicine in age aspect. Particular attention is given side effects probiotics contraindications their children.
Eosinophilic gastrointestinal disorders (EGID) are a kind of pathology which has not been well studied and trend to an increase during the last years that raises concern. They may have highly variable clinical manifestations; therefore, their differential diagnosis is infrequently challenging. The article presents review scientific data on EGID three cases various eosinophilic lesions stomach gut in children. Clinical manifestations depend location depth lesions. first case presented with...
The clinical guidelines for the diagnosis and treatment of the3 functional disorders digestive system in children were prepared by a Group Experts, domestic leading specialists field pediatric gastroenterology, who generalized foreign experience, suggesting tactics pediatrician actions everyday practice. Part 3 Guidelines discusses billiard tract dysfunctions constipations. There are no biliary Pediatric Sections Rome Consensus IV; however, Russian school thought has always considered them...
Autoimmune pancreatitis (AP) is not well-known disorder, it hasn’t been described in children yet. Current data about epidemiology, mechanisms of development, pathological and clinical signs AP are descripted the article, including international criterions its diagnosis. Among 57 with confirmed diagnosis chronic 4 correspond to criteria AP. 2 from had primary AP, rest - secondary associated inflammatory bowel disease. Primary prominent manifestation immunological markers AP: high level IgG4,...
This paper highlights the influence of intensity oxidative stress on hemorheology parameters
 in complicated and uncomplicated acute myocardial infarction patients with diabetes type 2. The
 study was performed by analyzing results examination treatment 66 patients, men aged 65,6 ± 5,8
 years old, suffering from coronary heart disease clinical manifestations and
 concomitant Depending presence failure were divided into 2
 groups. 1st group consisted 34 without...
The appearance of new high-tech microbiological research methods has significantly changed the understanding human microbiome. purpose meeting Council Experts "Dysbiosis. immediate and long-term consequences microbiome disorders options for their correction with probiotics" was definition modern positions about possible studying intestinal microbiome, possibilities correcting dysbiosis, use Saccharomyces Boulardii CNCM I-745 to correct in various clinical situations. microbiota large...
Autoimmune pancreatitis (AIP) in children is a rare disease that requires close clinical attention. Late diagnosis increases the risk of complications. There are only sporadic case reports pediatric AIP medical literature, making it difficult to diagnose. Objective. To specify and diagnostic characteristics children. Patients methods. The study included 13 patients with (6 girls 7 boys), mean age at was 10.7 years. made according INSPPIRE criteria. Clinical, laboratory instrumental signs...
The study is devoted to the comparison of results rapid urease tests (RUT) and data obtained in histological examination. For this purpose, semi-quantitative assessment activity two BUTs was compared: Pronto Dry (GASTREX, France) widely used Europe AMA RUT Expert M test registered Russia (AMA LLC, Russia) with by PCR analyses. High correlation indices according both as well these examination analysis established.
Authors represent the Russia’s first clinical case description of a pediatric patient with ulcerative colitis whose diagnosis was combined Lambert-Eaton myasthenic syndrome (LEMS), rare autoimmune disorder neuromuscular junction transmission. The observed draws specialists’ attention to complexity and importance multidisciplinary approach in management such patients. Another purpose increase physicians’ awareness LEMS thereby reducing period needed establishing diagnosis, which its turn...
Prevalence of small intestinal bacterial overgrowth (SIBO) syndrome, improved diagnostic accuracy and therapeutic approaches require further study. The purpose this research was to evaluate the effect hydrogen dominant or hydrogen-producing SIBO (H-SIBO) methane methane-producing (M-SIBO) types on severity clinical manifestations in children with functional dyspepsia (FD). Materials methods used: a single-center cross-sectional study 90 pediatric patients: 41 (45.6%) aged 11.0 [9.0:13.0] y/o...