A5079599083- Integrated Water Resources Management
- Environmental Chemistry and Analysis
- Wastewater Treatment and Nitrogen Removal
- Membrane Separation Technologies
- Waste Management and Environmental Impact
- Renewable energy and sustainable power systems
- Engine and Fuel Emissions
- RNA and protein synthesis mechanisms
- Plant Molecular Biology Research
- RNA Research and Splicing
- Biochemical and Molecular Research
- Water Quality Monitoring and Analysis
- Microbial bioremediation and biosurfactants
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Odor and Emission Control Technologies
- Sustainable Development and Environmental Management
- Advanced oxidation water treatment
- Industrial Gas Emission Control
- Phosphorus and nutrient management
- Advanced Glycation End Products research
- Adenosine and Purinergic Signaling
- Forensic Toxicology and Drug Analysis
- RNA modifications and cancer
- Supramolecular Self-Assembly in Materials
West Pomeranian University of Technology
2016-2020
Institute of Biochemistry and Biophysics, Polish Academy of Sciences
2013-2019
Zachodniopomorskie Centrum Onkologii
2016
Activation of the receptor for advanced glycation end products (RAGE) leads to a chronic proinflammatory signal, affecting patients with variety diseases. Potentially beneficial modification RAGE activity requires understanding signal transduction mechanism at molecular level. The ligand binding domain is structurally uncoupled from cytoplasmic domain, suggesting oligomerization requirement activation. In this study, we used hydrogen-deuterium exchange and mass spectrometry map structural...
The human GW182 protein plays an essential role in micro(mi)RNA-dependent gene silencing. miRNA silencing is mediated, part, by a C-terminal region called the domain, which interacts with poly(A) binding and CCR4-NOT deadenylase complex to repress synthesis. Structural studies of this fragment are challenging due its predicted intrinsically disordered character, except for RRM domain. However, detailed insights into properties proteins containing regions can be provided hydrogen–deuterium...
SNF1-related protein kinases 2 (SnRK2s) are key signaling elements regulating abscisic acid-dependent plant development and responses to environmental stresses. Our previous data showed that the SnRK2-interacting Calcium Sensor (SCS) inhibits SnRK2 activity. Use of alternative transcription start sites located within Arabidopsis (Arabidopsis thaliana) AtSCS gene results in two in-frame transcripts subsequently proteins, differ only by sequence position N terminus. We previously described...
RACK1 is a member of the WD repeat family proteins and involved in multiple fundamental cellular processes. An intriguing feature its ability to interact with at least 80 different protein partners. Thus, structural features enabling such interactomic flexibility are great interest. Several previous studies crystal structures orthologs described detailed architecture confirmed predictions that adopts seven-bladed β-propeller fold. However, this did not explain bind We performed...
This paper describes the investigations on possibilities of treatment wastewater generated in an industrial laundry with application a combined biological-photooxidation- membrane system aimed at water recycle and reuse. The two schemes were compared: 1) scheme A consisting moving bed biological reactor (MBBR) followed by microfiltration (MF) nanofiltration (NF), 2) B comprising MBBR oxidation photolysis enhanced situ O3 (UV/O3) after which MF NF applied. removal efficiency reached 95–97%...
This research carried out membrane bioreactor (MBR) pilot plant tests on the treatment of industrial laundry wastewater as well making an analysis MBR operational conditions.The experiments were in-place at large-scale in Poland with usage real wastewater.The used worked under aerobic wastewater, containing mainly surfactants and impurities originating from washed fabrics, was supplemented a solution urea to increase nitrogen content acid adjust pH.Daily flow raw equal 0.25-0.5 m 3 /d hourly...
The biologically active form of purine nucleoside phosphorylase (PNP) from Escherichia coli (EC 2.4.2.1) is a homohexamer unit, assembled as trimer dimers. Upon binding phosphate, neighboring monomers adopt different site conformations, described open and closed. To get insight into the functions two distinctive virtually inactive Arg24Ala mutant complexed with phosphate; all sites are found to be in conformation. understand how communicate each other, we have combined H/D exchange (H/DX)...
Large laboratory scale biological treatment test of industrial real wastewater, generated in big laundry, has been conducted the period May 2016–August 2016. The research aimed at selection laundry wastewater technology included tests two-stage Moving Bed Bio Reactor (MBBR), with two reactors filled carriers Kaldnes K5 (specific area – 800 m2/m3), have realized aerobic condition. Operating on site, fed from retention tank. To contained mainly surfactants and impurities originating washed...
Laboratory tests simulating the process of polluting stormwater with fuels and subsequent treating in a separator oil derivative substances were conducted.Diesel (pure diesel abbreviated as DERV -diesel-engine road vehicle), bio-components, pure biofuel -BIO100 subject tests.Depending on kind fuel, differences concentration derivatives treated samples observed.The total reduction contaminants after 2 min separation amounted to 91% for BIO100, about 94% almost 99% DERV, however, 10 s...
The aim of the research was testing moving bed biofilm reactor (MBBR) pilot plant treatment efficiency industrial laundry wastewater.The two-stage MBBR filled with AnoxKaldnes TM (Lund, Sweden) Z-MBBR carriers (Z-400) used.The test carried out on a place in chosen usage real worked aerobic conditions coarse bubble aeration system daily wastewater flow (Q d ) equal to 0.6 m 3 /d (hourly Q h = 25 L/h).The hydraulic retention time 10.4 h.The concentration dissolved oxygen tanks maintained level...
Laboratory tests were conducted simulating the process of polluting stormwater with fuels and afterwards treating this sewage in separator oil derivative substances. The diesel - ON pure biofuel BIO 100, available on market, subject tests. Depending kind fuel, differences concentration substances “treated” range several hundred percent. Such big show necessity for examination whether assumptions accepted while designing separators will also be correct case polluted contemporary includuing biofuels.
In 2011–2013, research on the fertilizer value of slag from incineration municipal sewage sludge as an alternative source phosphorus was carried out. The scheme included 5 variants (in 4 repetitions) fertilization cultivated for grain with mineral fertilizers and ash. (P1, P2 P3 – consecutive doses ash) combustion: NK, NPK, NK+P1, NK+P2 NK+P3. obtained results indicate that average three years research, straw spring rape heat combustion 15.99 MJ/kg d.m., corn 16.20 triticale 17.06 d.m....
Alzheimer's disease (AD) is a neurodegenerative correlated with aggregation of A β peptide to form insoluble intracellular deposits composed fibrils in neuronal cells. The growing body evidence suggests that the plasma membrane neural cells plays an essential role pathophysiology AD. One observed pathological events AD disruption calcium ions homeostasis. This effect thought be mediated by interaction species lipid components membrane, possibly leading insertion into and formation ion...