A5062590522- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Lower Extremity Biomechanics and Pathologies
- Tendon Structure and Treatment
- Cardiovascular Function and Risk Factors
- Dental Radiography and Imaging
- Spectroscopy Techniques in Biomedical and Chemical Research
- Spine and Intervertebral Disc Pathology
- Epilepsy research and treatment
- Veterinary Equine Medical Research
- Memory and Neural Mechanisms
- Dental Implant Techniques and Outcomes
- Connective tissue disorders research
- Endodontics and Root Canal Treatments
- Advanced MRI Techniques and Applications
- Tribology and Lubrication Engineering
- Infrared Thermography in Medicine
- Cardiac Imaging and Diagnostics
- Neuroscience and Neuropharmacology Research
Kuopio University Hospital
2020-2023
Imaging Center
2020
University of Eastern Finland
1991-2018
Articular cartilage undergoes structural and biochemical changes during maturation, but the knowledge on how these relate to articular function at different stages of maturation is lacking. Equine samples four levels (newborn, 5-month-old, 11-month-old adult) were collected (N = 25). Biomechanical tensile testing, Fourier transform infrared microspectroscopy (FTIR-MS) polarized light microscopy used study tensile, properties cartilage, respectively. The modulus was highest breaking energy...
Introduction One of the characteristics early osteoarthritis (OA) is loss fixed charged density (FCD) glycosaminoglycans in superficial zone articular cartilage. However, possible local changes FCD content pericellular matrix (PCM) are not fully understood. Hence, our aim was to investigate effect unilateral anterior cruciate ligament transection (ACLT) rabbit knees on estimated PCM compared that ECM, and relate these results with cell morphology. Methods Articular cartilage samples were...
The structural integrity and mechanical environment of the articular cartilage matrix directly affect chondrocyte deformations. Rabbit models early osteoarthritis at 9 weeks following anterior cruciate ligament transection (ACLT) have been shown to alter deformation behavior superficial zone chondrocytes in mechanically loaded cartilage. However, it is not fully understood whether these changes cell mechanics are caused by macromolecules extracellular matrix. Therefore, purpose this study...
To compare the image quality produced by equivalent low-dose and default sinus imaging protocols of a conventional dental cone-beam computed tomography (CBCT) scanner, an extremity CBCT scanner clinical multidetector (MDCT) scanner.Three different phantoms were scanned using dose-neutral ultra-low-dose protocols, as well each device. Quantified parameters included modulation transfer function (MTF) to characterize spatial response system, contrast-to-noise ratio, low contrast visibility,...
To differentiate healthy from artificially degraded articular cartilage and estimate its structural, compositional, functional properties using Raman spectroscopy (RS).Visually normal bovine patellae (n = 12) were used in this study. Osteochondral plugs 60) prepared either enzymatically (via Collagenase D or Trypsin) mechanically impact loading surface abrasion) to induce mild severe damage; additionally, control 12). spectra acquired the samples before after artificial degradation....
Objectives Myocardial SPECT/CT imaging is frequently performed to assess myocardial perfusion and dynamic parameters of heart function, such as ejection fraction (EF). However, potential pitfalls exist in the chain that can unfavorably affect diagnosis treatment. We a national cardiac quality control study investigate how much protocols vary between different nuclear medicine units Finland, this may EF values. Methods Altogether, 21 participated with 27 traditional systems two...