A5103252311- Shoulder Injury and Treatment
- Venous Thromboembolism Diagnosis and Management
- Hip disorders and treatments
- Food Quality and Safety Studies
- Phytochemicals and Antioxidant Activities
- Muscle Physiology and Disorders
- Central Venous Catheters and Hemodialysis
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Estrogen and related hormone effects
- Total Knee Arthroplasty Outcomes
- Tea Polyphenols and Effects
- Shoulder and Clavicle Injuries
- Peroxisome Proliferator-Activated Receptors
- Pesticide Residue Analysis and Safety
- Exercise and Physiological Responses
- Effects and risks of endocrine disrupting chemicals
- Ginseng Biological Effects and Applications
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Pharmacological Effects of Natural Compounds
- Vascular Procedures and Complications
- Seaweed-derived Bioactive Compounds
- Adipokines, Inflammation, and Metabolic Diseases
- Diagnosis and Treatment of Venous Diseases
Kangwon National University
2022-2025
Obesity is a global health concern. Recent research has suggested that the development of anti-obesity ingredients and functional foods should focus on natural products without side effects. We examined effectiveness underlying mechanisms Brassica juncea extract (BJE) in combating obesity via experiments conducted both vitro vivo models. In controlled environment, application BJE demonstrated ability to suppress accumulation lipids induced by MDI 3T3-L1 adipocytes. Additionally, it...
June-Seok Lim, Geon Oh, Ji-Hyun Im, Xiaolu Fu, Min-Hye Kim, Jin-Ho Roh, and Ok-Hwan Lee. Journal of the Korean Society Food Science Nutrition 2025;54:195-201. https://doi.org/10.3746/jkfn.2025.54.2.195
Barley sprouts, rich in bioactive compounds, have gained attention as functional food ingredients because of their antioxidant potential. This study evaluated composition and capacity, focusing on the saponarin, chlorophyll, policosanol, total polyphenol (TP), flavonoid (TF) contents. The capacity was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), ferric-reducing power (FRAP) assays. results showed that barley sprouts...
In many countries, thiabendazole is used as a fungicide to prevent the decay of food and lengthen storage periods. However, in Korea, unauthorised does not have standards or specifications for use additive. this study, simple analytical method was developed validated using HPLC–PDA detect foods frequently consumed South Korea. The calibration curve obtained samples solid liquid containing banana citrus fruits concentrations range 0.31–20.00 μg/mL with satisfactory coefficient determination...
Obesity is a global health concern. Recent research has suggested that the development of anti-obesity ingredients and functional foods should focus on natural products without side effects. We investigated efficacy mechanisms action Brassica juncea extract (BJE) using in vitro vivo obesity models. In experiments, BJE treatment downregulated adipogenic-related proteins CCAAT/enhancer-binding protein-α (C/EBP-α), peroxisome proliferator-activated receptor-γ (PPAR-γ), adipocyte protein 2...
This study aims to develop and validate a method for simultaneously measuring three azo dyes (azorubine, brilliant black BN, lithol rubine BK) not designated in Korea. The HPLC-PDA analysis was validated based on the ICH guidelines, color stability evaluated. milk cheese samples were spiked with dyes, correlation coefficient of calibration curve ranged from 0.999 1.000 recovery rates 98.81 ∼ 115.94%, RSD 0.08 3.71%. LOD LOQ 1.14 1.73 μg/mL 3.46 5.25 μg/mL, respectively. In addition, expanded...
With the increase in bone metabolic diseases owing to aging of global population, interest functional food ingredients for improving health is increasing. This study aimed determine anti-osteoporosis effect Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid ovariectomy (OVX)-induced osteoporosis female ICR mice. Thirty-five mice underwent OVX or sham operation were randomized into seven groups five animals as follows: normal, sham, OVX, with genistein (10 mg/kg), (20 LBHE (100 HBHE...
Fermented red ginseng (FRG) enhances the bioactivity and bioavailability of ginsenosides, which possess various immunomodulatory, antiaging, anti-obesity, antidiabetic properties. However, effects FRG extract on muscle atrophy underlying molecular mechanisms remain unclear. This study aimed to elucidate using both in vitro vivo models. In experiments used dexamethasone (DEX)-induced C2C12 myotubes assess cell viability, myotube diameter, fusion index. were conducted hind limb immobilization...
Geun hee Cho, June seok Lim, Ji-Hyun Geon Oh, Xiaolu Fu, Xiao Men, Sun-Il Choi, and Ok-Hwan Lee. Journal of the Korean Society Food Science Nutrition 2024;53:452-8. https://doi.org/10.3746/jkfn.2024.53.5.452
Black rice (BR) is considered one of the healthiest foods worldwide. This study assessed bioactive compound contents and antioxidant activities distilled water (DW) 80% ethanol (EtOH) extracts BR, black bran (BRB), milled (MBR). In addition, their anti-obesity, anti-obesogenic, anti-muscle atrophy effects were comparatively evaluated. The results revealed that EtOH extract BR contained higher β-glucan, total flavonoids, phenolics (26.97 ± 0.70 mg gallic acid equivalents (GAE)/g 16.58 0.37...
Fermentation is a process that improves health functionality by inducing the production and increase of bioactive compounds. In this study, to standardize fermentation for Benincasa hispida, marker compounds are increased or produced during were identified based on UPLC-QTOF-MS/MS. Analysis method verification content analysis conducted using HPLC-PDA. The in as 2-furoic acid, 2,3-dihydroxybenzoic rubinaphthin A comparing their retention times, UV MS spectra, molecular formulas with those...
June seok Lim, Geun hee Cho, Xionggao Han, Xiao Men, Se-jeong Lee, Geon Oh, Sun-Il Choi, Wha Young and Ok-Hwan Lee. Journal of the Korean Society Food Science Nutrition 2023;52:473-81. https://doi.org/10.3746/jkfn.2023.52.5.473
본 연구는 아티초크 추출물과 유산균을 이용하여 발효물을 제조하고 발효 전후의 pH, 산도, 항산화 효능 분석을 위한 목적으로 수행하였다. 실험에 사용된 시료는 분쇄 분말과 건조된 꽃 차를 구입하여 사용하였다. 발효물의 pH 측정값은 후 전체적으로 감소하였으며, 분말의 중에서 L. plantarum 로 발효한 것이 3.34±0.01에서 2.80±0.01로 감소하여 가장 낮은 pH를 나타냈다. 산도 증가하는 경향을 나타내었으며, 0.81±0.00 %에서 1.71±0.00 %로 높았다. Folin-Denis법을 변형하여 총 폴리페놀 함량(㎎ GAE/g)을 측정한 결과 발효를 통해 분말 72.10±0.30 ㎎ GAE/g에서 18.8 % 까지 증가되었다. DPPH radical 소거능(㎎ AEAC/g)은 39.34±0.38 AEAC/g에서 51.3 증가하였다. 전체 조건에서 함량과 소거능이 최댓값을 발효물에서 fermentum 과 P. pentosaceus 에 비해 결과를 나타내었다....