Obesity is a global health concern. Recent research has suggested that the development of anti-obesity ingredients and functional foods should focus on natural products without side effects. We examined effectiveness underlying mechanisms Brassica juncea extract (BJE) in combating obesity via experiments conducted both vitro vivo models. In controlled environment, application BJE demonstrated ability to suppress accumulation lipids induced by MDI 3T3-L1 adipocytes. Additionally, it...

Geun-Hee Cho, Ji-Hyun Im, Sieun Yu, Chaebin Park, Chan Lee, Hee-Jae Suh, Ok-Hwan and Sun-Il Choi. Journal of the Korean Society Food Science Nutrition 2025;54:202-6. https://doi.org/10.3746/jkfn.2025.54.2.202

Tae-Woong Song, Geun-Hee Cho, Da-Hyun Ko, Aram Sung Phil Kim, Ok-Hwan Lee, and Sun-Il Choi. Journal of the Korean Society Food Science Nutrition 2025;54:140-8. https://doi.org/10.3746/jkfn.2025.54.2.140

Rice bran, a by-product derived from processing rice, is rich source of bioactive compounds. Recent studies have suggested that the fermentation can improve their biological activities. This study aimed to determined level γ-oryzanol, β-glucan and total phenol contents fermented rice bran 21 Korean varieties, as well evaluate antioxidant We also assessed validation analytical method for determining γ-oryzanol content in brans. Among brans, Haedam contained highest (156.08 mg gallic acid...

Antioxidants are used to prevent the oxidation of foods. When for food additive purposes, dosage should be regulated and functionality evaluated ensure stability. In this study, we performed a method validation quantitative analysis rosemary extract residues antioxidant activity in matrices. The validated was able determine under optimized high-performance liquid chromatography-photodiode array (HPLC-PDA) conditions. Furthermore, by peroxide value, acid terms residual levels lard oil. For...

Lilium lancifolium is native to Northeast Asia and its bulbs have been used for medicinal treatment. Moreover, Japan has using L. more actively as food ingredients than Korea. Therefore, this study was investigate the characteristics of Korean bulbs, with respect component functionality. As a result proximate composition analysis, an abundant carbohydrate content. HPLC analysis indicated p-coumaric acid ferulic contents extract were 1.14 ± 0.01, 1.46 0.00 mg/g, but only less detected in...

The antioxidant and anti-adipogenic activities of a mixture Nelumbo nucifera L., Morus alba Raphanus sativus were investigated their anti-obesity established in vitro vivo. Among the 26 different mixtures extraction solvent ratios, ethanol extract no. 1 (EM01) showed highest (α,α-Diphenyl-β-picrylhydrazyl, total phenolic contents) (Oil-Red O staining) activities. EM01 inhibited lipid accumulation 3T3-L1 adipocytes compared to quercetin-3-O-glucuronide. Furthermore, body, liver, adipose...

Processed products from agricultural produce generate a large number of by‑products that contain functional substances. These are often discarded owing to the lack suitable processing methods. The present study investigated anti‑photoaging properties fermented rice bran (FRB), soybean cake (FSB) and sesame seed (FSC) on ultraviolet B (UVB)‑irradiated hairless mouse skin. Results indicated oral administration FRB, FSB FSC effectively inhibited UVB irradiation‑induced expression matrix...

In many countries, thiabendazole is used as a fungicide to prevent the decay of food and lengthen storage periods. However, in Korea, unauthorised does not have standards or specifications for use additive. this study, simple analytical method was developed validated using HPLC–PDA detect foods frequently consumed South Korea. The calibration curve obtained samples solid liquid containing banana citrus fruits concentrations range 0.31–20.00 μg/mL with satisfactory coefficient determination...

Glucoraphanin (GRA), a glucosinolate particularly abundant in broccoli (Brassica oleracea var. italica) sprouts, can be converted to sulforaphane (SFN) by the enzyme myrosinase. Herein, we investigated anti-obesogenic effects of sprout powder (BSP), mustard (Sinapis alba L.) seed (MSP), and sulforaphane-rich MSP-BSP mixture (MBP) bisphenol A (BPA)-induced 3T3-L1 cells obese C57BL/6J mice. In vitro experiments showed that MBP, BSP, MSP have no cytotoxic effects. Moreover, MBP BSP inhibited...

Ultraviolet (UV) radiation stimulates the expression of matrix metalloproteinases (MMPs) and inflammatory cytokines. These signaling pathways participate in degradation extracellular induce responses that lead to photoaging. This study evaluated antioxidant activity effect on MMPs procollagen putgyul extract vitro. The anti-photoaging extracts was estimated vivo using hairless mice (HR-1). reduced MMP-1 production increased content type I carboxy-terminal peptide human dermal fibroblasts....

The purpose of this study was to compare the nutritional components and antioxidant activities two different cultivars Brassica juncea (Dolsan, Yeosu, Korea (BJD) (Jeongseon, Gangwon, (BJJ)). We investigated proximate composition (moisture, crude ash, protein lipid), (2,2-Diphenyl-2-picrylhydrazil (DPPH) scavenging activity ferric reducing power (FRAP)), total phenol content, flavonoid content sinigrin by high-performance liquid chromatography analysis. Our results show that compositions BJD...

Obesity is a global health concern. Recent research has suggested that the development of anti-obesity ingredients and functional foods should focus on natural products without side effects. We investigated efficacy mechanisms action Brassica juncea extract (BJE) using in vitro vivo obesity models. In experiments, BJE treatment downregulated adipogenic-related proteins CCAAT/enhancer-binding protein-α (C/EBP-α), peroxisome proliferator-activated receptor-γ (PPAR-γ), adipocyte protein 2...

Endocrine disrupting chemicals (EDCs) disrupt the physiological metabolism, thus playing an important role in development of obesity. EDCs, so-called ‘obesogens’, might predispose some individuals to gain weight. This study investigated effects bisphenol A (BPA) and its alternatives (BPS BPF) on adipocyte differentiation leaves Potentilla rugulosa Nakai extract (LPE) as a functional food ingredient obesogen-induced lipid production adipogenesis 3T3-L1 cells. The results showed that LPE has...

This study aims to determine the immunomodulatory effects of a polysaccharide fraction from fermented

This study aims to develop and validate a method for simultaneously measuring three azo dyes (azorubine, brilliant black BN, lithol rubine BK) not designated in Korea. The HPLC-PDA analysis was validated based on the ICH guidelines, color stability evaluated. milk cheese samples were spiked with dyes, correlation coefficient of calibration curve ranged from 0.999 1.000 recovery rates 98.81 ∼ 115.94%, RSD 0.08 3.71%. LOD LOQ 1.14 1.73 μg/mL 3.46 5.25 μg/mL, respectively. In addition, expanded...

Aster scaber is a wild vegetable cultivated in Korea and known to contain phytochemicals with various biological activities. The potential antioxidant anti-obesity effects of A. their mechanism are yet be reported. We evaluated the total phenolic, flavonoid, proanthocyanidin contents oxygen radical absorbance capacity ethanolic extract (ASE), analyzed major phenolic compounds ASE. Antioxidant activity was measured at chemical level through 2,2-diphenyl-1-picrylhydrazyl (DPPH), reducing power...

Fermentation is a technology that enhances biologically active ingredients, improves the absorption rate and induces generation of new functional ingredients by catalytic action enzyme systems possessed microorganisms. In this study, changes in content five kinds bioactive compounds (deacetylasperulosidic acid, asperulosidic scopolin, asperuloside scopoletin) Morinda citrifolia L. were confirmed fermentation, high-performance liquid chromatography-photodiode array (HPLC-PDA) analysis method...

Liriope platyphylla is a medical herb that has long been used in Korea and China to treat cough, sputum, neurodegenerative disorders, obesity, diabetes. The aims of this study were determine the antidiabetic antiobesity effects aqueous extract L. (AEtLP) through glucose lipid regulation both pre-diabetes obesity stage type II diabetes model. Two concentrations AEtLP orally administrated OLETF (Otsuka Long-Evans Tokushima Fatty) rats once day for 2 weeks, after which changes metabolism fat...

Sesame is an important oilseed crop, which has been used as a traditional health food to ameliorate the prevention of various diseases. We evaluated changes in anti-allergic activities sesame by bioconversion. SDS-PAGE non-fermented proteins showed major allergen bands, while that fermented only few protein bands. Additionally, we investigated effectiveness bioconversion tumor necrosis factor-α (TNF-α)- and interferon-γ (IFN-γ)-induced HaCaT cells. In cells, inhibited mRNA expression...

With the increase in bone metabolic diseases owing to aging of global population, interest functional food ingredients for improving health is increasing. This study aimed determine anti-osteoporosis effect Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid ovariectomy (OVX)-induced osteoporosis female ICR mice. Thirty-five mice underwent OVX or sham operation were randomized into seven groups five animals as follows: normal, sham, OVX, with genistein (10 mg/kg), (20 LBHE (100 HBHE...