A5018256442- Advanced NMR Techniques and Applications
- Molecular spectroscopy and chirality
- Soil Carbon and Nitrogen Dynamics
- Quantum Dots Synthesis And Properties
- Plant Pathogens and Fungal Diseases
- Protein Structure and Dynamics
- Physiological and biochemical adaptations
- Nanocluster Synthesis and Applications
- Plant Pathogens and Resistance
- Neurobiology and Insect Physiology Research
- Reproductive Biology and Fertility
- Botany and Plant Ecology Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Bacterial Genetics and Biotechnology
- Powdery Mildew Fungal Diseases
- Photoreceptor and optogenetics research
- Supramolecular Self-Assembly in Materials
- NMR spectroscopy and applications
- Solid-state spectroscopy and crystallography
- Forest ecology and management
- Mycorrhizal Fungi and Plant Interactions
- Advanced biosensing and bioanalysis techniques
- Museums and Cultural Heritage
- Porphyrin and Phthalocyanine Chemistry
- Computational Drug Discovery Methods
University of New Hampshire
2016-2024
Magyar Agrár- és Élettudományi Egyetem
2021-2024
Eötvös Loránd University
2023
University of Szeged
2022
University of Debrecen
2019-2021
Boys Town
2021
University of New Hampshire at Manchester
2016-2018
Sapientia Hungarian University of Transylvania
2015-2018
University of Wyoming
2011-2016
University of Southampton
2016
Amending soil with biochar (pyrolized biomass) is suggested as a globally applicable approach to address climate change and degradation by carbon sequestration, reducing soil-borne greenhouse-gas emissions increasing nutrient retention. Biochar was shown promote plant growth, especially when combined nutrient-rich organic matter, e.g., co-composted biochar. Plant growth promotion explained slow release of nutrients, although mechanistic understanding storage in missing. Here we identify...
Chiral thiol capping ligands l- and d-cysteines induced modular chiroptical properties in achiral cadmium selenide quantum dots (CdSe QDs). Cys-CdSe prepared from oleic acid capped CdSe by postsynthetic ligand exchange displayed size-dependent electronic circular dichroism (CD) circularly polarized luminescence (CPL). Opposite CPL signals were measured for the QDs with d- l-cysteine. The CD profile anisotropy varied size of nanocrystals largest observed nanoparticles 4.4 nm. Magic angle...
L-cysteine derivatives induce and modulate the optical activity of achiral cadmium selenide (CdSe) sulfide (CdS) quantum dots (QDs). Remarkably, N-acetyl-L-cysteine-CdSe L-homocysteine-CdSe as well N-acetyl-L-cysteine-CdS L-cysteine-CdS showed "mirror-image" circular dichroism (CD) spectra regardless diameter QDs. This is an example inversion CD signal QDs by alteration ligand's structure, rather than absolute configuration. Non-empirical chemical simulations were able to reproduce...
Significance Despite being the simplest organisms, bacteria have complex subcellular anatomies. How does such organization occur in openly diffusive cytoplasm? We find that cell pole organizing protein PopZ facilitates network formation by binding directly to at least eight other proteins. The region is intrinsically disordered, suggesting has a flexible structure adopts different interface for each partner protein. In this way, resembles eukaryotic hub proteins, as p53 and BRCA1, which...
Semiconductor cadmium selenide (CdSe) quantum dots (QDs) exhibited mirror-image circular dichroism (CD) spectra in the visible region (350–570 nm) after replacing trioctylphosphine oxide/oleic acid ligands on achiral nanocrystals with D- and L-cysteines. Chiroptical properties of cysteine-capped CdSe QDs depend their size can be fine-tuned by changing radius QDs.
Functionalization of colloidal quantum dots (QDs) with chiral cysteine derivatives by phase-transfer ligand exchange proved to be a simple yet powerful method for the synthesis chiral, optically active QDs regardless their size and chemical composition. Here, we present induction chirality in CdSe thiol-free carboxylic acid capping ligands (l- d-malic tartaric acids). Our circular dichroism (CD) infrared experimental data showed how presence on surface was necessary but not sufficient...
In this work the physico-chemical properties of selected cryoprotectants (antifreeze protein TrxA-AFP752, trehalose and dimethyl sulfoxide) were correlated with their impact on constitution ice influence frozen/thawed cell viability. The freezing processes states investigated materials solutions described explained from a fundamental point view using ab-initio modelling (molecular dynamics, DFT), Raman spectroscopy, Differential Scanning Calorimetry X-Ray Diffraction. For first time, in we...
Making complements: Solid-state MAS NMR spectra of bacteriorhodopsin in its native purple membrane environment can be used to complement crystallographic studies the protein by validating and redefining (possibly distorted) loop structures. Backbone dihedral angles were extracted from chemical shifts compared crystal Where there are conformational differences, recalculate structure (see picture). Detailed facts importance specialist readers published as "Supporting Information". Such...
Abstract In this work, we shed new light on the highly debated issue of chromatin fragmentation in cryopreserved cells. Moreover, for first time, describe replicating cell-specific DNA damage and higher-order alterations after freezing thawing. We identified structural changes associated with freeze-thaw process correlated them viability frozen thawed simultaneously evaluated defects structure cells without cryoprotectant treatment. found that (S phase) cells, was preferentially damaged by...
Cell cryopreservation is an essential part of the biotechnology, food, and health care industries. There a need to develop more effective, less toxic cryoprotective agents (CPAs) methods, especially for mammalian cells. We investigated impact insect antifreeze protein from Anatolica polita (ApAFP752) on cell using human embryonic kidney line HEK 293T. An enhanced green fluorescent (EGFP)-tagged protein, EGFP–ApAFP752, was transfected into cells GFP used determine efficiency transfection. AFP...
Ionic liquids have great potential in biological applications and biocatalysis, as some ionic can stabilize proteins enhance enzyme activity, while others the opposite effect. However, on molecular level, probing liquid interactions with proteins, especially solutions containing high concentrations of liquids, has been challenging. In present work 13C, 15N-enriched GB1 model protein was used to demonstrate applicability high-resolution magic-angle-spinning (HR-MAS) NMR spectroscopy...
The mechanisms underlying cell protection from cryoinjury are not yet fully understood. Recent biological studies have addressed cryopreserved survival but correlated the cryoprotection effectiveness with impact of cryoprotectants on most important structure, nucleus, and freeze/thaw process. We identified changes nuclei states caused by different types associate them alterations process in cells. Namely, we investigated both higher-order chromatin structure nuclear envelope integrity as...
We studied CdS QDs capped with chiral epimers, structural analogs, and positional isomers determined that match/mismatch stereo-effects together position type of functional group affect the optical chiroptical properties CdS.