- Acute Ischemic Stroke Management
- Peripheral Neuropathies and Disorders
- Stroke Rehabilitation and Recovery
- Autoimmune Neurological Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Multiple Sclerosis Research Studies
- Vascular Malformations Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Long-Term Effects of COVID-19
- Neurosurgical Procedures and Complications
- CNS Lymphoma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Cerebral Venous Sinus Thrombosis
- Genetic Neurodegenerative Diseases
- RNA regulation and disease
- Ophthalmology and Eye Disorders
- Venous Thromboembolism Diagnosis and Management
- Renal Diseases and Glomerulopathies
- Cerebrovascular and Carotid Artery Diseases
- Vasculitis and related conditions
- Neurobiology of Language and Bilingualism
- Sarcoidosis and Beryllium Toxicity Research
- Neurological Disorders and Treatments
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals
2010-2025
Government Medical College
2019-2024
Fortis Hospital
2017-2023
Government Medical College
2023
Creative Commons
2023
University of Calgary
2011
Safdarjang Hospital
1993
To determine the association of ultraearly hematoma growth (uHG) with CT angiography (CTA) spot sign, expansion, and clinical outcomes in patients acute intracerebral hemorrhage (ICH).We analyzed data from 231 enrolled multicenter Predicting Haematoma Growth Outcome Intracerebral Haemorrhage Using Contrast Bolus study. uHG was defined as baseline ICH volume/onset-to-CT time (mL/h). The sign used marker active hemorrhage. parameters included significant expansion (>33% or >6 mL, primary...
There is a high burden of stroke, including recurrent in India. We aimed to assess the effect structured semi-interactive stroke prevention package patients with subacute reduce strokes, myocardial infarction, and death.This was multicentre, randomised, clinical trial conducted 31 centres Indian Stroke Clinical Trial Network (INSTRuCT). Adult first access mobile cellular device were randomly allocated (1:1) intervention control groups by research coordinators at each centre using central,...
Background This study evaluates the efficacy and safety of tenecteplase, a newer thrombolytic agent, in acute ischaemic stroke (AIS) at tertiary public care centre Western India. Methods retrospective analysed 30 patients with AIS treated presenting within 4.5 hours from onset receiving 0.25 mg/kg tenecteplase. Primary outcomes were achieving modified Rankin Scale (mRS) score 0-1 90 days those showing an improvement National Institutes Health Stroke (NIHSS) by 4 after 24 thrombolysis. The...
Many countries have seen an unprecedented rise of cases coronavirus disease 2019 (COVID-19) associated mucormycosis (CAM). Cerebrovascular involvement in CAM has not been studied so far. We describe clinico-radiological manifestations cerebrovascular complications observed CAM.
Background: The clinical phenotypes of myelin oligodendrocyte glycoprotein (MOG) antibody disease, its disease course, and treatment are poorly understood much work needs to be done towards this. Objective: To characterize the clinico-radiologic spectrum outcomes MOG differentiate it from aquaporin-4 (AQP-4) positive neuromyelitis optica disorders (NMO-SD). Methods: A single-center, observational study Western India during 2017–2019, 48 patients with either (21 patients) or AQP-4 (27 central...
Introduction:In a developing country like India, it is imperative to study the effects of age and gender on incidence stroke as has important implications in making health policy decisions. Methods:We evaluated patients over 15 years at Navi Mumbai, India during period 2013-19 India.Outcomes studied were stratified by age, sex, subtype.Results: Out total 1377 patients, 1246 ischemic 131 haemorrhagic.The mean was 49.06 53% males.Nearly half strokes occurred 46-65 group, one-thirds 65 age.21%...
Background: Mechanical thrombectomy (MT) is the most effective treatment in large vessel occlusion (LVO). We have analyzed our initial experience of MT 137 patients anterior circulation (AC) and posterior (PC) LVO using Solitaire stent retriever device. Methods: Retrospective cohort analysis 112 AC 25 PC acute ischemic strokes was done considering various baseline characteristics, risk factors, National Institute Health Stroke Scale (NIHSS) change, revascularization rate, complications,...
Discovery of serum myelin oligodendrocyte glycoprotein (MOG) antibody testing in demyelination segregated MOG-IgG disease from AQ-4-IgG positive NMOSD.To study clinico-radiological manifestations, pattern laboratory and electrophysiological investigations response to treatment through follow up patients.Retrospective data patients was collected. Demographics, clinical manifestations at onset relapses, anti status, imaging all were performed, relapses further immunomodulatory therapy...
Aphemia is an apraxia of speech characterized by complete articulatory failure in the presence preserved writing, comprehension and oropharyngeal function can be presenting manifestation acute stroke. The responsible lesion commonly left inferior frontal gyrus or motor cortex near face M1 area. Three patients who developed aphemia due to ischemic stroke are described here. All had infarct Understanding underlying disorder crucial planning appropriate rehabilitation strategy.
Myasthenia gravis (MG) is an autoimmune disease affecting the neuromuscular junction, and in over 80% of cases, antibodies are identified against nicotinic type acetylcholine receptor (AChR) on muscle endplate. Despite availability various treatment options, patients with MG experience relapses remission during course disease. Aims Objective: To understand clinical profile, predictors outcomes acetyl choline antibody positive generalized MG.This a retrospective, single-centre, observational...
Background and Purpose: Very few large scale multicentric stroke clinical trials have been done in India. The Indian Council of Medical Research funded INSTRuCT (Indian Stroke Clinical Trial Network) as a task force project with the objectives to establish state-of-the-art trial network conduct pharmacological nonpharmacological relevant nation globally. purpose article is enumerate structure network, emphasis on its scope, challenges expectations Methods: Multiple expert group meetings were...
Introduction: A better understanding of etiology might improve poor outcomes trochlear headaches (TRHs). Aims: To study clinical spectrum, etiology, and therapeutic response TRH. Methods: Fifty-three TRH patients seen in a single center between 2015 2020 were included, excluding Trigeminal Autonomic Cephalalgia (TAC). Results: Mean age was 36.45 years (range 11–85 years), with 77.35% being females. Twenty-five had continuous headache (CTRH) 28 episodic (ETRH). Tension-type (TTH) occurred 9...
Abstract Background and Objectives: Sensory neuronopathies (SNNs) are a rare group of pure sensory disorders causing asymmetrical, multifocal pattern loss with distinct clinical electrophysiological features. We aimed to study the features etiology share experience treating SNN from our center. Methods: A prospective observational was conducted over 3 years. Patients predominant complaints evidence neuropathy were evaluated. Possible/probable diagnosed using Camdessanch´e criteria. Detailed...
Maniyar, Aamna M. H.; Singh, Rakesh K.; Ojha, Pawan T.; Chaudhary, Gaurav S.; Mahto, Anuradha P.; Shah, Arjun G. Author Information
Background Repetitive Transcranial Magnetic Stimulation (r-TMS), a non-invasive brain stimulation method, appears promising in augmenting post-stroke recovery and requires further evaluation. Aims Objective To study the effect of r-TMS treatment on motor function patients with strokes different duration types. Methods A prospective, single center was conducted to bilateral cortex rTMS 100 consecutive either ischemic or hemorrhagic stroke any duration. Measured outcomes were changes NIHSS,...